MASTER'S DEGREE IN CHEMISTRY

- Review of thermodynamics of single-component systems.

- Basic concepts of thermodynamics in multicomponent systems. Chemical potential, Gibbs-Duhem relation, variance.

- Concepts related to thermal analysis techniques used to construct binary/ternary diagrams: ATG, ATD, and DSC

- Construction and interpretation of binary phase diagrams based on thermodynamic quantities. Gibbs free enthalpy, pressure, and temperature diagrams as a function of the composition of the binary mixture. Liquid-liquid, liquid-vapor, and solid-liquid mixtures.

- Phase transformations: first- and second-order transitions, critical points. Examples.

- The supercritical state: definition, thermodynamic properties, most widespread industrial applications.

- Construction and interpretation of ternary phase diagrams: variance, definitions of ternary eutectic, first and second order peritectic, isothermal section, study of alloy cooling.

Hourly volumes:

CM: 13

TD: 7

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This course on solution chemistry aims to introduce the various concepts necessary for studying complex liquid mixtures used in separation chemistry. The approach taken is mainly thermodynamic. In particular, we explain the role of concentration effects, beyond the ideal laws that apply only to dilute solutions.

CM: 12 H

Tutorial: 8 hours

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This lecture, delivered entirely in English, provides a basic introduction to crystallography and electron diffraction for beginners. X-ray diffraction is an important characterization technique in modern chemistry; the majority of crystalline structures in inorganic and organic solids have been solved using this method. It is therefore important for all students to understand its basic concepts and instrumentation. The course provides explanations and principles of X-ray diffraction together with the geometry and symmetry of X-ray patterns. In addition to the interaction principles of X-rays and matter, it covers how to obtain quantitative intensities for single crystal and powder diffraction patterns. It naturally includes an understanding of lattice planes and the reciprocal lattice concept together with the Ewald sphere construction. Furthermore, it provides a basic understanding of the Fourier transform relationship between the crystalline structure and the diffracted intensities, as well as the reciprocal lattice concept.

Electron diffraction is a complementary technique to X-rays that provides information in terms of symmetry and geometry on the materials studied. In this course, we will therefore approach the description of the method for obtaining electron diffraction patterns and their interpretation. We will be able to obtain the lattice parameters, the reflection conditions, as well as the groups of possible spaces.

This lecture also serves as the introductory part to the lecture Electron Microscopy and Crystallography II.

CM: 14

TD: 6

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Knowledge of the latest mass spectrometry techniques for the qualitative analysis of organic molecules and biomolecules.

1) Description of fundamental principles (Ion science and technology):

- Ionization techniques

- Analysis techniques

- Tandem mass spectrometry (MS/MS)

- LC/MS and LC/MS/MS couplings

2) Application in the context of biomolecule analysis and monitoring of organic chemistry reactions.

Hourly volumes*:

CM: 3 p.m.

Tutorial: 5 hours

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Polymers are all around us: we eat them, we wear them, and we use them to construct extremely complex buildings. From mature technologies to the most innovative materials, polymers are a crucial building block for constructing the world of tomorrow. In this course, we will cover several aspects such as the controlled synthesis of polymers and cross-linked materials, surface modification using polymers, some characterization tools suitable for polymers, and finally a last section developing the latest advances involving polymers.

Hourly volumes:

            CM: 1:00 p.m.

            Tutorial: 7 hours

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The HAC720C module covers "advanced inorganic materials" in five main sections. The^first section is devoted to general information on inorganic materials and discusses structure-property relationships, with particular attention paid to chemical bonding, real crystals, and polycrystalline solids. The different classes of inorganic materials are described. The^second part focuses on ceramic materials (definitions and properties) and their synthesis (raw materials including clays, shaping, drying and debinding, sintering); a distinction is made between traditional ceramics and technical ceramics (synthesis methods for oxide and non-oxide ceramics). The^third part covers glass (classification and synthesis methods) and glass-ceramics (devitrification and soft chemistry); their properties and applications are also discussed. The^fourth part is dedicated to metals: properties of metals and metal alloys; metal nanoparticles; and catalytic materials. Part⁵ is devoted to inorganic materials developed for energy; ceramics (oxides and non-oxides; nanostructured) and metal hydrides are described (properties and synthesis) through several examples and in the context of their applications (accumulators, hydrogen storage, and carbon dioxide capture).

Hourly volumes:

CM: 1:00 p.m.

Tutorial: 7 hours

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This course unit enables students to acquire basic knowledge and cross-disciplinary skills in the field of colloids and interfaces, which are common to the various tracks of the Master's degree in Chemistry (Materials Chemistry, Separative Chemistry, Materials and Processes, ICAP Cosmetics Engineering, Biomolecular Chemistry). It is also offered to international students enrolled in the SFRI program at the University of Montpellier, where courses are taught in English. An introductory presentation on basic notions and concepts will enable students to discover and better understand the main physicochemical properties of colloidal dispersions, associative colloids, and macromolecular solutions, as well as the parameters and phenomena governing stability in colloidal dispersions and mixed solution-colloid systems. This will be followed by interdisciplinary practical teaching based on the flipped classroom principle to help students build and deepen their knowledge through individual and collective analysis of the various applications of colloidal and interfacial phenomena and systems.

Hourly volumes:

CM: 7

TD: 13

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NMR:

Liquid-phase NMR (Nuclear Magnetic Resonance) is an essential spectroscopic analysis method for chemists, enabling them to determine the structure of small organic molecules or macromolecules in solution, study dynamic phenomena, and more. The aim of this course unit is to understand the phenomena involved in this technique and to relate them to the various structural information accessible by this method. The goal is to be able to use the spectral data from this analysis to elucidate the structure and stereochemistry of organic molecules or polymer structures, or to monitor reactions.

X-ray diffraction:

X-ray diffraction is a powerful, non-destructive technique for characterizing the crystalline structure of materials. It can also provide crystallographic and structural information such as lattice parameters and atomic positions. This includes all crystallized materials such as ceramics, materials for energy and information storage and conversion, as well as organic molecules and metal complexes (interatomic distances and angles, stereochemistry (chirality, stereoisomerism, etc.), intra- and intermolecular bonds, etc.). The objective of this course unit is to provide an introduction to crystallography and diffraction, with the aim of understanding the operation and characteristics of an X-ray diffractometer, as well as interpreting diffraction patterns (structural analysis, lattice parameters).

Hourly volumes:

            CM: 10

            TD: 10

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This course will cover the fundamental concepts and practical tools related to chemometrics through: - statistical data analysis;

• the laws of probability;
• confidence interval estimation;
• parametric and nonparametric tests.

An introduction to design of experiments will be offered at the end of the module.

Hourly volumes:

CM: 7 a.m.

TD: 1:00 PM

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The first part of the course presents the fundamental knowledge of organometallic chemistry of transition metals. It begins with a description of the metal-carbon bond, enabling an understanding of its stability and chemical reactivity.  Next, we will demonstrate the power of this synthesis tool for forming C-H, C-C, and other bonds. Examples of their applications in different fields will help students learn about these reactions and their fields of application: fine chemistry, catalytic transformations of industrial importance, synthesis of natural products, and preparation of materials.

The second part of this course is devoted to the chemistry of heteroelements, focusing on silicon, tin, and boron. This part aims to present the different methods of preparing boron-, tin-, and silicon-based reagents, as well as the main transformations carried out with these compounds, with applications in organic synthesis and materials synthesis.

CM: 1:00 PM 

Tutorial: 7 hours

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The program of this EU focuses on describing the principles and applications of the main methods for the structural characterization of solids, thin films, surfaces, and interfaces, as well as several examples of applications in materials chemistry. It includes the following techniques.

• Introduction to solid-state NMR (NMR signal, interactions in solid-state NMR, magic angle spinning, NMR sequences, cross polarization, instrumentation, etc.)
• Electron microscopy: principles and applications of scanning and transmission electron microscopy and related techniques (EDS microanalysis).
• Spectroscopic methods: Raman spectroscopy, photoelectron spectroscopy, X-ray spectroscopy (XAS, XRF, etc.), Mössbauer spectrometry.

Hourly volumes:

            CM: 10 a.m.

            Tutorial: 10 a.m.

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This teaching unit is dedicated to deepening the foundations of organic chemistry and coordination chemistry covered in L3 and to acquiring concepts related to molecular engineering and molecular chemistry. The teaching unit consists of lectures and tutorials. Students will prepare for certain lectures and tutorials using course materials provided, enabling them to participate fully in the lectures and tutorials, understand the concepts presented, and acquire the necessary skills. The progression program and activities will be proposed. For students who have not studied the basics of coordination chemistry and organic chemistry, documents will be made available.

Coordination chemistry: The course will cover various aspects of transition metal and lanthanide complexes, molecular materials (polynuclear complexes and coordination polymers with extended structures (MOFs, etc.)) as well as their properties and applications. Structural aspects, bond descriptions, properties, and aspects related to stability and reactivity will be addressed. Emphasis will be placed on the complexation effect and the stability of metal, lanthanide, and actinide complexes with certain ligands for applications in the biomedical field (imaging and therapy), decontamination (nuclear field), etc. The electronic (relaxivity, magnetism) and optical (absorption, luminescence) properties of these complexes will be discussed and placed in the context of applications in various fields, such as imaging, electronics, sensors, etc.

Organic Chemistry: The course builds on the knowledge acquired in the Bachelor's degree and will use a reasoned study approach to address the main reaction mechanisms in organic chemistry, providing a common foundation for all students in the Master's in Chemistry program. The main processes (substitution, addition, elimination, transposition, etc.) and their essential characteristics and applications to mechanistic sequences will be examined. This course should provide students with general tools for analyzing mechanisms (ionic, radical, concerted) in order to understand these mechanisms in all their variety.

Hourly volumes:

CM: 1:00 PM

Tutorial: 7 hours

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The professional project bridges the gap between traditional practical work and internships in laboratories or companies. It takes the form of a supervised project consisting of placing students in a professional situation through collaborative (group) work based on carrying out a project in response to a problem set by a company, local authority, association, or academic. It is part of the core curriculum of the Master's in Chemistry and is carried out under the supervision of a member of the teaching team (academic or industrial). Conducted throughout the semester, this project aims to connect and consolidate the knowledge and skills acquired during the Bachelor's and early Master's programs through this professional situation. These scenarios will be directly related to the Master's program chosen by the students. In addition to chemistry-specific skills, other interpersonal, organizational, and communication skills intrinsically linked to project management will also be acquired, equipping students for their future professional lives.

Addressing a research issue: example of a summary of new phosphorescent materials.

Hourly volumes:

CM: 5 hours

Tutorial: 5 hours

Practical work: 40 hours

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The internship in semester 8 of the Master 1 in Biomolecular Chemistry aims to familiarize students with careers in life sciences research. Students will have the opportunity to complete this introductory research internship in academic or private laboratories. Subject to prior approval by the teaching team (internship topic related to the Master's program and appropriate environment/resources), students may seek a host team in an academic setting at one of the institutes of the Chemistry Cluster at the University of Montpellier (IBMM, ICGM, , etc.), in academic laboratories outside the University of Montpellier (in France or abroad), or in the private sector (chemical, pharmaceutical, and agri-food industries, biotechnology laboratories, etc.).

Fieldwork: 2 to 4 months of internship

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The goal of this course is to enable students with a background in chemistry to understand the fundamentals of process engineering.

The course consists of two main parts that are illustrated by the same process.

In the first part of the course, a drying process will be used to introduce the most common heat and mass transfer phenomena found in process engineering, from which the dimensionless numbers can be derived. In the second part, the thermodynamic properties of the air/water vapor mixtures will be used to derive basic dimensioning rules for the same drying process.

This course will be taught entirely in English.

Hourly volumes:

CM: 10

TD: 10

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The following topics will be covered:

- Bio-based solvents

- Fuels derived from biomass

- Antioxidants derived from lignin

- Metal catalysts derived from plants

- Surfactants obtained from renewable resources

- Examples of industrial applications of enzymatic synthesis

Hourly volumes*:

CM: 15

TD: 5

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A general approach to liquid-liquid extraction will be developed through thermodynamics and kinetics concepts with a view to understanding the mechanisms responsible for extraction and the processes taking place at the liquid-liquid interface. The fundamental aspects of other types of extraction (liquid-solid, supercritical fluid, distillation) will also be addressed.

Hourly volumes:

            CM: 12 p.m.

            Tutorial: 8 hours

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The aim of teaching medicinal chemistry is to introduce students to the key stages in the process of developing molecules with biological activities. In particular, a description of the interactions involved, the concept of pharmacophores, bioisosterism, etc., as well as structure-activity relationship studies will be covered, enabling students to consider appropriate strategies and structural modifications.

Hourly volumes:

CM: 3 p.m.

Tutorial: 5 hours

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This teaching unit is shared by MI students in the Master's in Chemistry program: ICAP P1, ICAP P2, MAT P1, MAT P2, and BM (semester S2) courses. The following topics will be covered:

• The 12 Principles of Green Chemistry and units of measurement in Green Chemistry;
• Synthesis strategies in sustainable chemistry;
• Alternative or eco-friendly solvents for synthesis and extraction;
• Unconventional activation techniques and applications.

CM: 13

Tutorial: 7 hours

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The mechanical and thermal properties of materials are central to many applications in the field of energy materials. After an introduction to these different fields of application, this course unit aims to define the various concepts necessary for understanding both the mechanical and thermal properties of materials, limiting itself to bulk materials.

Hourly volumes:

            CM: 11 a.m.

            TD: 9 a.m.

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General overview of the most commonly used calculation and modeling methods in the field of solid-state chemistry according to the spatial and temporal scales that can be studied with them:

(1) Quantum calculations (Hartree Fock, Post-Hartree Fock methods, DFT),

(2) Force field-based modeling (atomistic and coarse-grained),

(3) Hybrid QMMM and AACG modeling.

Presentation of different calculation techniques: static and optimization calculations, molecular dynamics, and Monte Carlo.

The EU will offer lectures and practical classes. Two practical modeling assignments will be offered: modeling techniques in classical mechanics and quantum calculations.

            CM: 11 a.m.

            TD: 9 a.m.

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This teaching unit is dedicated to the presentation of inorganic materials and nanomaterials intended for use in the biomedical field (imaging, therapy, implants). This teaching unit builds on the knowledge acquired in teaching unit HAC930C (Development of Materials for Health). It aims to develop health issues and inorganic materials and nanomaterials in diagnosis, therapy, and well-being. Strategies for developing the inorganic materials and nanomaterials of the future based on theranostics and multifunctionality, as well as smart materials, will also be addressed.

The EU includes lectures and tutorials. Students will be offered a group project on the (theoretical) study of inorganic materials or nanomaterials for health.    

CM: 11

 TD: 9

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This EU will address, in small groups or on an individual basis, teaching tools and best practices related to communication and professional integration, through:

• assessment of knowledge, skills, competencies, interpersonal skills, and motivations;
• awareness of job search techniques;
• writing resumes and cover letters;
• rules for oral and written communication;
• job interview simulations.

Scenarios directly related to the sectors of activity targeted by the courses of the students concerned will be offered.

Practical work: 20 hours

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The electronic and optical properties of solids are central to many applications in the fields of energy (photovoltaic panels, passive coolants, etc.), light production (white diodes, lasers, etc.), and electronics (components, microprocessors, etc.). After an introduction to these different fields of application, this course aims to define the various concepts necessary for mastering both the electronic and optical properties of materials, which are essential for understanding the most modern technologies.

Hourly volumes:

            CM: 11 a.m.

            TD: 9 a.m.

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Hybrid materials are a new family of materials combining organic ligands that connect inorganic entities, and are increasingly being studied at both a fundamental and applied level.

As part of this course unit, two main categories of hybrid materials will be covered:

• Coordination Networks and Metal-Organic Frameworks
• Organosilicon/carbon materials

CM: 10 a.m.

Tutorial: 10 a.m.

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The theoretical knowledge necessary for understanding, formulating, and implementing dispersed systems will be detailed in this module. The physicochemical principles governing the preparation and stability of solid-liquid and liquid-liquid dispersions will be detailed in accordance with specifications and expected usage properties. The various concepts covered include powder dispersibility, modification of the solid/liquid interface to control zeta potential and colloidal interactions (extended DLVO), and rheology of dispersed systems in relation to the state of dispersion. Liquid-liquid dispersion: emulsification, Winsor's R ratio, formulation using the HLD method, and formulation maps.

Introduction to synthesis techniques in dispersed media: emulsion synthesis of nanoparticles, latex, microcapsules, etc.

CM: 11

TD: 9

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Replacing petroleum-based materials is becoming an increasingly important issue from both a technological and economic perspective. This module enables students to acquire skills in the field of agropolymers, bio-based polymers, degradable materials, and biocomposites. New, more environmentally friendly synthesis methods will be presented with a view to preparing synthetic degradable polymers.

The degradation, biodegradation, and recyclability of polymers will also be discussed.

Hourly volumes:

            CM: 11CM

            TD: 9 TD

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The development of materials involves numerous coupled phenomena, some of which are linked to the nature of the materials and their intrinsic properties, while others are linked to the processes used during material and/or energy transformation operations. Morphogenesis is therefore the result of interdependent, coupled mechanisms, whose relative kinetics will lead to one structure or another. Mastering and controlling these coupled mechanisms requires a good understanding of the transformation dynamics of the materials themselves, as well as a precise description of the transfer and transport phenomena involved in the process. Integration into the reactive environment will be addressed at the end of the course unit.

Hourly volumes:

            CM: 11

            TD: 9

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One of the major issues related to the use of different materials in our daily lives is their durability and therefore their degradation. In this course, we will address issues related to the sustainability of materials (resources, reserves, criticality of materials, etc.) as well as methodologies for studying sustainability (types of surface/volume aging, temporal extrapolation, multi-scale, combination of effects, experimental representation, and industrial validation). This will then allow us to model the kinetics of aging using different models.

The different types of degradation affecting polymers will then be analyzed.

Finally, the aging of different types of materials will be illustrated by various concrete case studies (concrete, ceramics, metals, and elastomers).

Hours per week*: 11 hours CM:

                                    9 a.m. tutorial

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The materials used in housing and road construction have a variety of characteristics and properties (durability, mechanical strength, thermal and acoustic insulation) that enable them to be adapted to the characteristics, implementation conditions, and cost specified in a set of technical specifications. This course provides basic knowledge on different types of materials used in housing (concrete, plaster, paint, adhesives, etc.) and road construction (asphalt) in terms of preparation, formulation, and implementation. For each of the materials presented, innovative approaches to reducing their ecological footprint while maintaining their performance will also be described.

Hourly volumes:

            CM: 11

            TD: 9

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The principles governing thermal energy exploitation sectors are addressed in this EU. After presenting the technological challenges and prospects associated with thermoelectric conversion and thermochemical storage, the focus is placed in particular on the design and development of functional materials for the direct conversion of thermal energy into electricity and for the storage of thermal energy by sorption.

Hourly volumes:

            CM: 11 a.m .

            Tutorial: 9 hours

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This teaching unit is dedicated to presenting materials and nanomaterials intended for use in the biomedical field (imaging, therapy, implants, etc.). The aim is to provide a representative overview of health issues where materials and nanomaterials play an essential role in diagnosis, therapy, and well-being. Strategies for developing the materials and nanomaterials of the future will also be discussed.

The prerequisites for developing materials for healthcare and their behavior/interaction with living organisms will be explained. Examples of inorganic materials and nanomaterials (inorganic nanoparticles, various materials for implants, etc.), organic materials (polymers, liposomes, etc.) and materials of biological origin used as contrast agents for various types of imaging, as therapeutic agents, or as implants will be presented.

The EU offers courses taught through lectures and tutorials. 

Hourly volumes:

            CM: 11

            TD: 9

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This teaching unit covers the various aspects of the current fuel cycle and future nuclear cycles. It will cover concepts relating to the front end of the cycle (mineral resources, uranium extraction and purification, isotopic enrichment), the passage of fuels through nuclear reactors, and the back end of the cycle (reprocessing of spent fuel, recycling of recoverable materials and fuel remanufacturing, management of final nuclear waste). This will be followed by several aspects relating to future nuclear fuel cycles, in particular the use of unconventional resources, advanced separation concepts, and the development of fourth-generation reactors.

Hourly volumes:

            CM: 3 p.m.

            Tutorial: 5 hours

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Metallurgy encompasses all industries and techniques involved in the processing of metals.

Hourly volumes:

            CM: 11

            TD: 9

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This EU will address the main conventional membrane technologies in liquid and gas environments. With regard to liquid environments, the focus will be on baromembrane technologies such as microfiltration, ultrafiltration, nanofiltration, and reverse osmosis, as well as technologies based on electrochemical potential gradients (electrodeionization) or temperature gradients (membrane distillation). In addition, gas permeation and pervaporation for the separation of gases and/or vapors will also be presented. For all technologies, the question of choosing suitable membrane materials will be addressed and representative examples of appropriate areas of use (related to current environmental and energy issues) will be given.

Hourly volumes:

            CM: 11 a.m.

            Tutorial: 9 a.m.

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This course will focus primarily on the energy context and methods of energy conversion and storage, the historical development of electrochemical energy conversion and storage technologies and modern applications, as well as electrochemical mechanisms. Finally, links will be made between modern energy conversion and storage technologies and current societal issues.

Hourly volumes:

            CM: 11

            TD: 9

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This course consists of an in-depth study of a selected problem or topic related to materials chemistry for the three targeted areas of the program: sustainable development, health, and membrane engineering. This may take the form of research, development, or analysis at the laboratory or company level. Students will work in small groups on projects. They will choose their topic and define the goal, objectives, and means under the guidance of a tutor. The ultimate goal is to develop a product/methodology using the synthesis and analysis knowledge already acquired in preparation for the internships that will take place in S8.  

Hourly volumes:

            CM: 6 hours

            Tutorial: 6 hours

            Practical work: 4 hours

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Membrane materials are usually divided into two families: polymer membranes and inorganic (or ceramic) membranes. Each of these families will be covered in this course unit. The first part will focus on the design of polymer membranes. In this part, we will mainly discuss phase inversion preparation techniques (NIPS, VIPS, TIPS) with an overview of research and innovation (SNIPS, aquaporin, etc.). In addition, additives (particularly porogens and hydrophilic agents), which play an important role in phase inversion approaches, will be described, and the various methods of chemical modification of post-synthesis membranes will be presented. The second part will be devoted to the design of inorganic membranes. In this part, we will present, on the one hand, wet processes, namely the main methods of liquid film deposition (dip-coating, spin-coating, spraying, tape-casting, screen printing-screen engraving) and deposition from solutions (electrolytic or chemical processes) or suspensions (electrophoresis, Langmuir-Blodgett), and dry processes (PVD techniques (evaporation and spraying), CVD techniques (thermal, PECVD, and ALD), MBE, surface treatment). Finally, to illustrate the two families of membranes, we will discuss case studies on membrane applications, particularly in the field of packaging.

Hourly volumes:

            CM: 11 a.m.

            Tutorial: 9 a.m.

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It is now essential to design products that are environmentally friendly throughout their entire life cycle. It is widely accepted that as a product progresses through the manufacturing stages, the technical choices available become more limited and the opportunities to reduce environmental impacts diminish accordingly. It is therefore necessary to integrate environmental considerations from the outset, i.e., at the product design stage.

The method is based on analyzing a product's life cycle. It takes into account factors such as:

• The choice of materials and raw materials
• The technologies used during the manufacture, use, maintenance, and disposal of the product.
• The product's lifespan and the possibility of recovering materials at the end of its life (recycling, etc.).
• Analysis of user behavior.

Hourly volumes:

            CM: 11 a.m.

            Tutorial: 9 a.m.

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This is a lecture course, primarily intended for students studying materials and sustainable development. It presents the role played by heterogeneous catalysis in the development of clean chemistry and in the depollution of gas/liquid effluents. The basic concepts of heterogeneous catalysis, as well as the main families of catalytic materials, will be discussed.  

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• Transport mechanisms in solids,
• Complex impedance spectroscopy
• Solid electrolyte electrochemical systems,
• Application in solid-state electrochemistry: energy and environment (batteries, accumulators, sensors, electrochromics, etc.)

Hourly volumes:

            CM: 11 a.m.

            TD: 9 a.m.

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This Master's 2 end-of-studies internship is designed to place students in a pre-professional situation, in an academic research laboratory or an industrial research and development laboratory, in France or abroad.  

The student will seek a host team in an academic setting at one of the institutes belonging to the Chemistry Cluster at the University of Montpellier (ICGM, IEM, IBMM, etc.), in academic laboratories outside the University of Montpellier (in France or abroad), or in the private sector working in the field of materials. The research project on which the student will work will have been validated in advance by the teaching team to ensure that the internship topic is related to the Master's program, the skills and expertise acquired during previous semesters, and the courses taken in semester 9 in particular, depending on the chosen specialization. In addition, the teaching team will ensure that the internship takes place in an appropriate environment and with adequate resources.

This internship, lasting 5 to 6 months, may begin in mid-January after the exam session and may not exceed 6 months in semester 10.

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Replacing petroleum-based materials is becoming an increasingly important issue from both a technological and economic perspective. This module enables students to acquire skills in the field of agropolymers, bio-based polymers, degradable materials, and biocomposites. New, more environmentally friendly synthesis methods will be presented with a view to preparing synthetic degradable polymers.

The degradation, biodegradation, and recyclability of polymers will also be discussed.

Hourly volumes:

            CM: 11CM

            TD: 9 TD

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Knowledge of the major families of polymers used in the biomedical field.

1) Specificity of polymers for biomedical applications and major families of polymers used

2) Description of application families

3) Discussion on the concept of synthesis and the relationship between structure, properties, and specifications

Hourly volumes*:

CM: 3 p.m.

Tutorial: 5 hours

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This teaching unit is dedicated to presenting materials and nanomaterials intended for use in the biomedical field (imaging, therapy, implants, etc.). The aim is to provide a representative overview of health issues where materials and nanomaterials play an essential role in diagnosis, therapy, and well-being. Strategies for developing the materials and nanomaterials of the future will also be discussed.

The prerequisites for developing materials for healthcare and their behavior/interaction with living organisms will be explained. Examples of inorganic materials and nanomaterials (inorganic nanoparticles, various materials for implants, etc.), organic materials (polymers, liposomes, etc.) and materials of biological origin used as contrast agents for various types of imaging, as therapeutic agents, or as implants will be presented.

The EU offers courses taught through lectures and tutorials. 

Hourly volumes:

            CM: 11

            TD: 9

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This course covers the various molecular and supramolecular tools used for vectorization and delivery of active ingredients according to the type of cells or intracellular organelles targeted. Ligand-receptor interactions will be discussed, as well as methods for preparing and activating conjugates. Examples of drugs will be presented.

Hourly volumes*:

CM: 3 p.m.

Tutorial: 5 hours

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This teaching unit is dedicated to the presentation of inorganic materials and nanomaterials intended for use in the biomedical field (imaging, therapy, implants). This teaching unit builds on the knowledge acquired in teaching unit HAC930C (Development of Materials for Health). It aims to develop health issues and inorganic materials and nanomaterials in diagnosis, therapy, and well-being. Strategies for developing the inorganic materials and nanomaterials of the future based on theranostics and multifunctionality, as well as smart materials, will also be addressed.

The EU includes lectures and tutorials. Students will be offered a group project on the (theoretical) study of inorganic materials or nanomaterials for health.

Hourly volumes:

            CM: 11

            TD: 9

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This teaching unit is dedicated to acquiring knowledge related to medical devices and biomaterials. The teaching unit includes traditional lectures and tutorials, as well as interactive lessons in the Learning Lab on issues related to innovation in medical devices. 

CM: 3 HCM

TD: 5HTD

12:00 p.m. CM-TD Learning Lab

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This course consists of an in-depth study of a selected problem or topic related to materials chemistry for the three targeted areas of the program: sustainable development, health, and membrane engineering. This may take the form of research, development, or analysis at the laboratory or company level. Students will work in small groups on projects. They will choose their topic and define the goal, objectives, and means under the guidance of a tutor. The ultimate goal is to develop a product/methodology using the synthesis and analysis knowledge already acquired in preparation for the internships that will take place in S8.  

Hourly volumes:

            CM: 6 hours

            Tutorial: 6 hours

            Practical work: 4 hours

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Membrane materials are usually divided into two families: polymer membranes and inorganic (or ceramic) membranes. Each of these families will be covered in this course unit. The first part will focus on the design of polymer membranes. In this part, we will mainly discuss phase inversion preparation techniques (NIPS, VIPS, TIPS) with an overview of research and innovation (SNIPS, aquaporin, etc.). In addition, additives (particularly porogens and hydrophilic agents), which play an important role in phase inversion approaches, will be described, and the various methods of chemical modification of post-synthesis membranes will be presented. The second part will be devoted to the design of inorganic membranes. In this part, we will present, on the one hand, wet processes, namely the main methods of liquid film deposition (dip-coating, spin-coating, spraying, tape-casting, screen printing-screen engraving) and deposition from solutions (electrolytic or chemical processes) or suspensions (electrophoresis, Langmuir-Blodgett), and dry processes (PVD techniques (evaporation and spraying), CVD techniques (thermal, PECVD, and ALD), MBE, surface treatment). Finally, to illustrate the two families of membranes, we will discuss case studies on membrane applications, particularly in the field of packaging.

Hourly volumes:

            CM: 11 a.m.

            Tutorial: 9 a.m.

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This EU will address the main conventional membrane technologies in liquid and gas environments. With regard to liquid environments, the focus will be on baromembrane technologies such as microfiltration, ultrafiltration, nanofiltration, and reverse osmosis, as well as technologies based on electrochemical potential gradients (electrodeionization) or temperature gradients (membrane distillation). In addition, gas permeation and pervaporation for the separation of gases and/or vapors will also be presented. For all technologies, the question of choosing suitable membrane materials will be addressed and representative examples of appropriate areas of use (related to current environmental and energy issues) will be given.

Hourly volumes:

            CM: 11 a.m.

            Tutorial: 9 a.m.

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This Master's 2 end-of-studies internship is designed to place students in a pre-professional situation, in an academic research laboratory or an industrial research and development laboratory, in France or abroad.  

The student will seek a host team in an academic setting at one of the institutes belonging to the Chemistry Cluster at the University of Montpellier (ICGM, IEM, IBMM, etc.), in academic laboratories outside the University of Montpellier (in France or abroad), or in the private sector working in the field of materials. The research project on which the student will work will have been validated in advance by the teaching team to ensure that the internship topic is related to the Master's program, the skills and expertise acquired during previous semesters, and the courses taken in semester 9 in particular, depending on the chosen specialization. In addition, the teaching team will ensure that the internship takes place in an appropriate environment and with adequate resources.

This internship, lasting 5 to 6 months, may begin in mid-January after the exam session and may not exceed 6 months in semester 10.

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This teaching unit is dedicated to acquiring knowledge related to pigments, dyes, and adsorbents, from the perspective of their structures and applications. Emphasis will be placed on applications in the field of flavors & fragrances (food coloring, perfumery) and cosmetics (hair coloring, powders, toothpaste, etc.). Some sessions are specific to each of the two tracks (P1, Cosmetics Engineering; P2, Flavors and Fragrances) of the Master's degree in Chemistry, specializing in Cosmetics, Flavors, and Fragrances Engineering (ICAP). The teaching unit includes lectures and tutorials.

Hourly volumes:

CM: 10 a.m.

Tutorial: 10 a.m.

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Some fundamental principles of microbiology will be covered to give students an overview of the diversity of microorganisms. The mode of nutrition and multiplication of bacteria according to the physicochemical parameters of the environment will be studied.

We will discuss the composition and role of the skin and digestive microbiota.

The microbiological criteria used for quality control of cosmetic and food products will be defined.

Physical and chemical antimicrobial agents that control microbial growth will be examined.

On a practical level, emphasis will be placed on ensuring that students know how to handle bacteria and are familiar with microbiological safety rules. Standard microbiological control and preservative efficacy techniques will be performed on cosmetic products.

Hourly volumes:

CM: 12 p.m.

Practical work: 8 hours

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This module covers all the knowledge about raw materials necessary to work in the cosmetics industry.

These are:

• describe the different chemical classes of raw materials, understand structure/activity relationships and sensory rendering.
• Study of documents relating to the marketing of cosmetic raw materials

Hourly volumes:

            CM: 18

            TD: 6

            TP: 16

The course is based on case studies of ingredients in aqueous or fatty phases, and polymers such as polymerization processes will be developed.

The practical part of the module will enable students to work with the main categories of raw materials:

Implementation of gelling agents: implementation, study of their properties, sensory evaluation

Implementation of surfactants: Formulation of a foaming product with ingredient research, formula design, and sensory evaluation.

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This EU addresses:

- the fundamentals of colorimetry, which enable an unambiguous measurement of color to be defined based on psychophysical experiments.

- the principle and practical use of color measuring devices (colorimeters and spectrocolorimeters).

- the principles of color reproduction, particularly in the context of perfumes and cosmetics.

The theoretical concepts are supplemented by a significant amount of observation and practical work during the practical sessions.

Hourly volumes:

CM: 12 p.m.

Practical work: 8 hours

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Study of the entire development process of a cosmetic product

• Definition of a cosmetic product
• Launch of development, interactions between the development department and the marketing, industry, and regulatory departments: needs, expectations, operations, and procedures
• Study of all possible tests: sensory analysis, physicochemical stability, safety and health safety, efficacy.
• Study of industrial transposition
• Study of interactions with packaging and associated tests
• Description of the product information file or legal cosmetic file

Study of emulsions, definitions, characteristics, and formulation

Study of emulsion instability phenomena and stabilization solutions

Practical part:

Formulation of water-in-oil, oil-in-water, and cream gel emulsions

Study of ingredients, chemical nature, physical behavior, and formulation

Study of formulation materials

Implementation of sensory, physicochemical, and stability tests.

Development of a multi-step formula with imposed constraints.

Critical analysis of the results obtained.

As regards the introduction to chemical engineering applied to the field of cosmetics, students will be required to work on a case study describing the laboratory-scale production of a cosmetic product, and then find a way to produce it on a larger scale.

Hourly volumes:

 CM: 15

TP: 25

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This course unit enables students to acquire basic knowledge and cross-disciplinary skills in the field of colloids and interfaces, which are common to the various tracks of the Master's degree in Chemistry (Materials Chemistry, Separative Chemistry, Materials and Processes, ICAP Cosmetics Engineering, Biomolecular Chemistry). It is also offered to international students enrolled in the SFRI program at the University of Montpellier, where courses are taught in English. An introductory presentation on basic notions and concepts will enable students to discover and better understand the main physicochemical properties of colloidal dispersions, associative colloids, and macromolecular solutions, as well as the parameters and phenomena governing stability in colloidal dispersions and mixed solution-colloid systems. This will be followed by interdisciplinary practical teaching based on the flipped classroom principle to help students build and deepen their knowledge through individual and collective analysis of the various applications of colloidal and interfacial phenomena and systems.

Hourly volumes:

CM: 7

TD: 13

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Know and be able to apply the various regulations relating to the cosmetics industry (Regulation 1223/2009, REACH, CLP, etc.).

In-depth analysis of key articles in European cosmetics regulations - Regulation 1223/2009

Learn how to create a DIP

Focus on the safety report using an example

Hourly volumes:

            CM: 10

            TD: 10

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This course will cover the fundamental concepts and practical tools related to chemometrics through: - statistical data analysis;

• the laws of probability;
• confidence interval estimation;
• parametric and nonparametric tests.

An introduction to design of experiments will be offered at the end of the module.

Hourly volumes:

CM: 7 a.m.

TD: 1:00 PM

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This course aims to teach liquid chromatography and gas chromatography.

Hourly volumes:

            CM: 3:00 p.m.

            Tutorial: 5 hours

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The professional project bridges the gap between traditional practical work and internships in laboratories or companies. It takes the form of a supervised project consisting of placing students in a professional situation through collaborative (group) work based on carrying out a project in response to a problem set by a company, local authority, association, or academic. It is part of the core curriculum of the Master's in Chemistry and is carried out under the supervision of a member of the teaching team (academic or industrial). Conducted throughout the semester, this project aims to connect and consolidate the knowledge and skills acquired during the Bachelor's and early Master's programs through this professional situation. These scenarios will be directly related to the Master's program chosen by the students. In addition to chemistry-specific skills, other interpersonal, organizational, and communication skills intrinsically linked to project management will also be acquired, equipping students for their future professional lives.

Addressing a research issue: example of a summary of new phosphorescent materials.

Hourly volumes:

CM: 5 hours

Tutorial: 5 hours

Practical work: 40 hours

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This module focuses on R&D in the cosmetics industry and will emphasize scientific expertise and innovation through lectures and conferences. Similarly, scenarios involving the design and development of cosmetics and wellness products will be proposed.

The practical part will focus particularly on the development of makeup products:

Review of the composition of makeup products

Natural or synthetic coloring raw materials. Understanding the different galenic formulations used in makeup and knowing how to select raw materials.

Know how to select pigments according to the desired target. Know how to disperse them and understand surface treatment.

Marketing study on specific makeup formulations

Theoretical courses on raw materials and galenics used in makeup, manufacturing processes, market trends, and possible tests (claims, physical and chemical tests, efficacy tests, etc.).

In practice:

Practical courses on pigment premixes, foundations, and lipsticks, combined with sensory evaluations

Application to the formulation of various makeup products (foundation, lipstick, mascara, etc.) and quality control of finished products.

Hourly volumes:

            CM: 20

            TD: 5

            TP: 15

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This teaching unit is shared by MI students in the Master's in Chemistry program: ICAP P1, ICAP P2, MAT P1, MAT P2, and BM (semester S2) courses. The following topics will be covered:

• The 12 Principles of Green Chemistry and units of measurement in Green Chemistry;
• Synthesis strategies in sustainable chemistry;
• Alternative or eco-friendly solvents for synthesis and extraction;
• Unconventional activation techniques and applications.

CM: 13

Tutorial: 7 hours

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This 4- to 6-month internship will be carried out in an R&D laboratory in the cosmetics and wellness industries.

The tasks assigned to the student intern by the company will be related to the objectives of the Master's program.

This internship can begin in February/March and will take place in France or abroad.

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This EU will address, in small groups or on an individual basis, teaching tools and best practices related to communication and professional integration, through:

• assessment of knowledge, skills, competencies, interpersonal skills, and motivations;
• awareness of job search techniques;
• writing resumes and cover letters;
• rules for oral and written communication;
• job interview simulations.

Scenarios directly related to the sectors of activity targeted by the courses of the students concerned will be offered.

Practical work: 20 hours

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This module focuses on:

• Tools and sources of information (patents, databases, journals, trade shows and scientific conferences, etc.) and communication: knowing how to identify relevant sources of information, how to analyze and use them, and how to communicate internally and externally.
• What is economic intelligence, how to understand it and how to use it
• Marketing fundamentals: presentation of what marketing does, presentation of tools that can help students in their future work, detailed explanation of the process of developing a cosmetic product in marketing, and the different careers available to students.

A project will be developed by the students.

Hourly volumes:

CM: 3:00 p.m.

Tutorial: 5 hours

Practical work: 10 hours

Departure: 10 a.m.

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A design of experimentsis an ordered sequence of tests in an experiment whose purpose is to test the validity of a hypothesis by reproducing a phenomenon and varying one or more parameters. Each test produces data, and all the data produced during an experiment must be analyzed using rigorous methods to validate or invalidate the hypothesis. This experimental approach allows new knowledge to be acquired by confirming a model in a cost-effective manner (using as few tests as possible, for example).

Starting with a simple problem, the module develops methodological and statistical tools that enable increasingly complex hypotheses to be tested in the most optimal way possible. These methodologies are implemented using the statistical language R.

Hourly volumes:

            CM: 3 p.m.

            Practical work: 5 hours

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Provide students with the theoretical understanding of inferential statistics necessary for the statistical analysis of data from sensory tests. General issue: extract interpretable patterns from sensory measurements in order to make the right decisions.

The lessons will cover the requirements of each course, using relevant examples and applications.

Hourly volumes*:

            CM: 10 AM

            Practical work: 10 hours

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Polymers are used in a wide range of cosmetic formulations with various functions, the main ones being rheology control, formulation stabilization, and conditioning. It is therefore important to understand their behavior in these complex environments, particularly by studying polymer-surfactant interactions, since these two components are often present together in these environments, as well as interactions with solid surfaces (suspensions, applications on hair or skin) or liquids (emulsions).

The course describes: (1) the different types of polymers used: water-soluble, synthetic, natural and semi-natural, amphiphilic, and structure-property relationships; (2) the principle of thickening formulas or gelation using polymers; (3) interactions with surfactants, presentation of the different types of surfactants and their physicochemical properties, in particular polymeric surfactants, (4) interactions with surfaces (skin, hair) as well as any type of solid surface, (5) the principle of stabilizing emulsions and suspensions using polymers.

The second part of this module focuses on silicones and their use in cosmetics:

The chemistry of silicones, silicones for cosmetics: categories, uses, and sensory effects with examples of application.

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Basic knowledge of skin structure and physiology: skin structure; sensory receptors; mechanical and thermal sensitivity.

Skin penetration; skin hydration and moisturizing products; seborrhea, acne; types Dermocosmetics: skin penetration; skin aging, infant skin; cellulite

Hourly volumes:

            CM: 16

            TD: 4

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This module is devoted to the study of the main classes of cosmetic additives on the one hand, and to the study of natural, biotechnological, and synthetic active ingredients on the other.

The first part of this course will focus on marine flora, particularly the general composition and specific characteristics of different types of algae. What is the role and effectiveness of marine flora in cosmetics?

The course will conclude with case studies and perspectives.

The second part will focus on the plant world, enabling formulators and regulatory affairs managers to understand how plant molecules can be used to achieve beneficial effects in relation to the main cosmetic indications. Essential oils: what are the production techniques, chemical compositions, cosmetic properties, formulations, and safety profiles?

The third part of the module will focus on the different classes of additives used in cosmetics.

The focus will be on the chemical and organoleptic study of the main raw materials (synthetic or natural) used in the fragrance of cosmetics and the regulatory constraints related to their use (cosmetic directives relating to the dosage of allergens).

The families of odor molecules used in cosmetics (molecules without organic functions or containing alcohol, aldehyde, ketone, or ester functions) will be studied:
- molecules with an aromatic ring
- phenol-type molecules
- cyclic and acyclic aliphatic molecules.
- acyclic and cyclic terpene molecules
- field of odors.

-Concepts of molecular stability and volatility.

The course will conclude with training in the formulation of fragrance compositions for cosmetic products.

Hourly volumes:

            CM: 20

            TD: 10

            TP: 10

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What is eco-design? 

Product Life Cycle Assessment (LCA)
Who certifies?
Eco-design & raw materials
Biodiversity and the Nagoya Protocol.
Reminders on the principles of green chemistry
Ecotoxicology and biodegradability
Manufacturing an eco-designed cosmetic product
Trends related to eco-design

Eco-designed packaging: what is its impact?

Concept of ecotoxicology: impact on the environment/biodegradability

Information on eco-design measures: what tools are available/impact assessment Recyclability of packaging: measurement and analysis (raw materials/formulas/ecotoxicology).

Students will be given a scenario to work with.

Hourly volumes:

            CM: 20

            TD: 10

            TP: 10

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The EU's objective is to understand and apply the principles of color formulation as practiced in the color industry. To this end, the basics of spectrocolorimetry, light-matter interactions, and the simplest formulation models (Beer-Lambert and Kubelka-Munk) are studied and used in practical work.

Hourly volumes:

            CM: 12

            TP: 8

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Reminder of European legislation and its hierarchy: regulations, directives, decisions, resolutions, national laws, institutions, and authorities in charge of the regulatory system.

Description of key regulations around the world and overview of progress

Institutions and authorities responsible for the regulatory system

Regulatory framework applicable to cosmetic packaging

The process of ensuring cosmetic packaging compliance and its main challenges

New requirements applicable to cosmetic packaging under European and French circular economy laws

The course will cover Good Manufacturing Practices (GMP) designed to ensure the reproducibility and quality of cosmetic products.

It will enable you to identify the measures to be taken with regard to production, control, storage, and shipping processes and to ensure the compliance of cosmetic products with current regulations (EC 1223/2009, ISO 22716 standard, etc.).

Hourly volumes:

            CM: 15

            TD: 15

            Land: 10

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This module covers all aspects of photoprotection:

He will begin with a reminder about solar radiation and the skin, emphasizing natural melanin and non-melanin photoprotection. The skin's reaction to the sun will allow us to discuss the benefits of the sun, but will focus mainly on the harmful side effects for the skin. What protection options does the cosmetics industry offer? How can we analyze the effectiveness of sunscreen products? What is the impact of filters on the environment?

• Study of the development of sunscreen formulas: raw materials, chemical and physical filters, formulation techniques, regulations, the relationship between the sun and the skin.

• Use of software for calculating theoretical SPFs

• Acquire knowledge in the formulation of sunscreen products
• Manufacturing processes
• Detailed analysis of INCI formulas

• Phase inversion microemulsion formulation

Hourly volumes:

            CM: 15

            TP: 25

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This teaching unit covers several areas:

• The lessons will show that chemistry opens up a variety of careers in the cosmetics industry, not just in formulation.

• Know how to reflect on the scientific method in order to avoid errors in judgment and know how to apply scientific thinking to any information. Teaching will be based on concrete examples related to cosmetics (difference between risk and danger, reflection on various applications/consumer information, etc.).

• A simulation exercise allows students to work on concrete marketing projects, from market research to the formalization of a marketing concept in cosmetics.

Hourly volumes:

            CM: 12

            TD: 8

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In-depth study of different cosmetic formulations: composition, description of main components, formulation, principle, dosage forms

Study of ingredient families including emollients, esters, emulsifiers, sunscreens, preservatives, and innovations in skincare and makeup products.

Study of INCI lists of formulations, INCI nomenclatures

Study of different types of cosmetics companies

Study of manufacturing processes (agitation equipment, complementary manufacturing processes, impact of physical and chemical parameters on manufacturing)

The application will be implemented in various fields.

For example: formulation of moisturizing emulsions with electrolytes (stability disruptors), formulation of cleansing milk and cleansing lotion and implementation of tests to measure cleansing effectiveness, formulation of makeup products.

Hourly volumes:

            CM: 15

            TP: 25

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This module consists of placing students in a professional context, in relation to a cosmetics development and production company or raw materials supplier. The module will be organized in the form of industrial projects:

Students are divided into groups, as would be the case in a scientific team. They will therefore have to apply their theoretical knowledge in close collaboration with the manufacturer. The manufacturer will be able to guide them or help them contact new suppliers, compile a cosmetics dossier, conduct market research, etc., depending on the project assigned.

Activity reports will be produced via the sharing networks commonly used in the industry. The groups will be required to work independently, following specifications defined by the manufacturer, in line with the diploma program.

This could involve, for example, developing an innovative product in compliance with French and European regulations, or countertyping.

Hourly volumes:

            CM: 10

            TP: 30

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This module will enable students to understand the importance of innovation in a sector as dynamic as cosmetics.

This environment is governed by regulatory constraints, innovations in packaging, innovations in formulation, and also in ingredients.

The whole thing is also governed by the expectations of increasingly demanding consumers.

It is therefore essential for these future graduates to understand the ins and outs of innovation in cosmetics and to know how to implement it while respecting certain criteria.

A project will be proposed to students: Presentation of the project in groups and establishment of guidelines for its implementation.

Hourly volumes:

            CM: 20

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This 5- to 6-month internship, or work-study program, will take place in an R&D laboratory in the cosmetics and wellness industries.

The tasks assigned by the company to the intern/work-study student will be related to the objectives of the Master's degree.

This internship or work-study placement will take place in France or abroad.

See the full page

This teaching unit is dedicated to acquiring knowledge related to pigments, dyes, and adsorbents, from the perspective of their structures and applications. Emphasis will be placed on applications in the field of flavors & fragrances (food coloring, perfumery) and cosmetics (hair coloring, powders, toothpaste, etc.). Some sessions are specific to each of the two tracks (P1, Cosmetics Engineering; P2, Flavors and Fragrances) of the Master's degree in Chemistry, specializing in Cosmetics, Flavors, and Fragrances Engineering (ICAP). The teaching unit includes lectures and tutorials.

Hourly volumes:

CM: 10 a.m.

Tutorial: 10 a.m.

See the full page

Some fundamental principles of microbiology will be covered to give students an overview of the diversity of microorganisms. The mode of nutrition and multiplication of bacteria according to the physicochemical parameters of the environment will be studied.

We will discuss the composition and role of the skin and digestive microbiota.

The microbiological criteria used for quality control of cosmetic and food products will be defined.

Physical and chemical antimicrobial agents that control microbial growth will be examined.

On a practical level, emphasis will be placed on ensuring that students know how to handle bacteria and are familiar with microbiological safety rules. Standard microbiological control and preservative efficacy techniques will be performed on cosmetic products.

Hourly volumes:

CM: 12 p.m.

Practical work: 8 hours

See the full page

This module covers all the knowledge about raw materials necessary to work in the cosmetics industry.

These are:

• describe the different chemical classes of raw materials, understand structure/activity relationships and sensory rendering.
• Study of documents relating to the marketing of cosmetic raw materials

Hourly volumes:

            CM: 18

            TD: 6

            TP: 16

The course is based on case studies of ingredients in aqueous or fatty phases, and polymers such as polymerization processes will be developed.

The practical part of the module will enable students to work with the main categories of raw materials:

Implementation of gelling agents: implementation, study of their properties, sensory evaluation

Implementation of surfactants: Formulation of a foaming product with ingredient research, formula design, and sensory evaluation.

See the full page

This EU addresses:

- the fundamentals of colorimetry, which enable an unambiguous measurement of color to be defined based on psychophysical experiments.

- the principle and practical use of color measuring devices (colorimeters and spectrocolorimeters).

- the principles of color reproduction, particularly in the context of perfumes and cosmetics.

The theoretical concepts are supplemented by a significant amount of observation and practical work during the practical sessions.

Hourly volumes:

CM: 12 p.m.

Practical work: 8 hours

See the full page

Study of the entire development process of a cosmetic product

• Definition of a cosmetic product
• Launch of development, interactions between the development department and the marketing, industry, and regulatory departments: needs, expectations, operations, and procedures
• Study of all possible tests: sensory analysis, physicochemical stability, safety and health safety, efficacy.
• Study of industrial transposition
• Study of interactions with packaging and associated tests
• Description of the product information file or legal cosmetic file

Study of emulsions, definitions, characteristics, and formulation

Study of emulsion instability phenomena and stabilization solutions

Practical part:

Formulation of water-in-oil, oil-in-water, and cream gel emulsions

Study of ingredients, chemical nature, physical behavior, and formulation

Study of formulation materials

Implementation of sensory, physicochemical, and stability tests.

Development of a multi-step formula with imposed constraints.

Critical analysis of the results obtained.

As regards the introduction to chemical engineering applied to the field of cosmetics, students will be required to work on a case study describing the laboratory-scale production of a cosmetic product, and then find a way to produce it on a larger scale.

Hourly volumes:

 CM: 15

TP: 25

See the full page

This course unit enables students to acquire basic knowledge and cross-disciplinary skills in the field of colloids and interfaces, which are common to the various tracks of the Master's degree in Chemistry (Materials Chemistry, Separative Chemistry, Materials and Processes, ICAP Cosmetics Engineering, Biomolecular Chemistry). It is also offered to international students enrolled in the SFRI program at the University of Montpellier, where courses are taught in English. An introductory presentation on basic notions and concepts will enable students to discover and better understand the main physicochemical properties of colloidal dispersions, associative colloids, and macromolecular solutions, as well as the parameters and phenomena governing stability in colloidal dispersions and mixed solution-colloid systems. This will be followed by interdisciplinary practical teaching based on the flipped classroom principle to help students build and deepen their knowledge through individual and collective analysis of the various applications of colloidal and interfacial phenomena and systems.

Hourly volumes:

CM: 7

TD: 13

See the full page

Know and be able to apply the various regulations relating to the cosmetics industry (Regulation 1223/2009, REACH, CLP, etc.).

In-depth analysis of key articles in European cosmetics regulations - Regulation 1223/2009

Learn how to create a DIP

Focus on the safety report using an example

Hourly volumes:

            CM: 10

            TD: 10

See the full page

This course will cover the fundamental concepts and practical tools related to chemometrics through: - statistical data analysis;

• the laws of probability;
• confidence interval estimation;
• parametric and nonparametric tests.

An introduction to design of experiments will be offered at the end of the module.

Hourly volumes:

CM: 7 a.m.

TD: 1:00 PM

See the full page

This course aims to teach liquid chromatography and gas chromatography.

Hourly volumes:

            CM: 3:00 p.m.

            Tutorial: 5 hours

See the full page

Professional placement for M1 ICAP apprenticeship students, who will carry out a project in response to an industrial problem. This project will be supervised by a member of the teaching team (academic or industrial). Conducted throughout the semester, this project aims to put into practice the knowledge and skills acquired during the Bachelor's degree and early Master's degree programs. In addition to chemistry-related skills, other interpersonal, organizational, and communication skills intrinsically linked to project management will also be acquired, preparing students for their future professional lives.

Example of an industrial issue: evaluation of the oxidative stability of fragrant ingredients in the presence of antioxidants

Example of an industrial problem: analysis of allergens in perfumes: solid-phase microextraction (SPME) technique of the headspace (HS) followed by analysis by gas chromatography coupled with mass spectrometry (GC-MS)

Examples of industrial issues: detection and identification of compounds responsible for off-flavors using gas chromatography coupled with olfactometry

Examples of industrial issues: Understanding and knowing how to use the essential physical and chemical analysis techniques used in the inspection of a finished product.

Hourly volumes:

            CM: 5 hours

            Tutorial: 5 hours

            Practical work: 40 hours

See the full page

This module focuses on R&D in the cosmetics industry and will emphasize scientific expertise and innovation through lectures and conferences. Similarly, scenarios involving the design and development of cosmetics and wellness products will be proposed.

The practical part will focus particularly on the development of makeup products:

Review of the composition of makeup products

Natural or synthetic coloring raw materials. Understanding the different galenic formulations used in makeup and knowing how to select raw materials.

Know how to select pigments according to the desired target. Know how to disperse them and understand surface treatment.

Marketing study on specific makeup formulations

Theoretical courses on raw materials and galenics used in makeup, manufacturing processes, market trends, and possible tests (claims, physical and chemical tests, efficacy tests, etc.).

In practice:

Practical courses on pigment premixes, foundations, and lipsticks, combined with sensory evaluations

Application to the formulation of various makeup products (foundation, lipstick, mascara, etc.) and quality control of finished products.

Hourly volumes:

            CM: 20

            TD: 5

            TP: 15

See the full page

This teaching unit is shared by MI students in the Master's in Chemistry program: ICAP P1, ICAP P2, MAT P1, MAT P2, and BM (semester S2) courses. The following topics will be covered:

• The 12 Principles of Green Chemistry and units of measurement in Green Chemistry;
• Synthesis strategies in sustainable chemistry;
• Alternative or eco-friendly solvents for synthesis and extraction;
• Unconventional activation techniques and applications.

CM: 13

Tutorial: 7 hours

See the full page

This EU corresponds to the work-study program carried out in an R&D laboratory in the cosmetics and wellness industries.

The tasks assigned to the work-study student by the company will be related to the objectives of the Master's degree.

The duration of the work placement for work-study students follows the work-study schedule proposed to partner companies.

See the full page

This EU will address, in small groups or on an individual basis, teaching tools and best practices related to communication and professional integration, through:

• assessment of knowledge, skills, competencies, interpersonal skills, and motivations;
• awareness of job search techniques;
• writing resumes and cover letters;
• rules for oral and written communication;
• job interview simulations.

Scenarios directly related to the sectors of activity targeted by the courses of the students concerned will be offered.

Practical work: 20 hours

See the full page

This module focuses on:

• Tools and sources of information (patents, databases, journals, trade shows and scientific conferences, etc.) and communication: knowing how to identify relevant sources of information, how to analyze and use them, and how to communicate internally and externally.
• What is economic intelligence, how to understand it and how to use it
• Marketing fundamentals: presentation of what marketing does, presentation of tools that can help students in their future work, detailed explanation of the process of developing a cosmetic product in marketing, and the different careers available to students.

A project will be developed by the students.

Hourly volumes:

CM: 3:00 p.m.

Tutorial: 5 hours

Practical work: 10 hours

Departure: 10 a.m.

See the full page

A design of experimentsis an ordered sequence of tests in an experiment whose purpose is to test the validity of a hypothesis by reproducing a phenomenon and varying one or more parameters. Each test produces data, and all the data produced during an experiment must be analyzed using rigorous methods to validate or invalidate the hypothesis. This experimental approach allows new knowledge to be acquired by confirming a model in a cost-effective manner (using as few tests as possible, for example).

Starting with a simple problem, the module develops methodological and statistical tools that enable increasingly complex hypotheses to be tested in the most optimal way possible. These methodologies are implemented using the statistical language R.

Hourly volumes:

            CM: 3 p.m.

            Practical work: 5 hours

See the full page

Provide students with the theoretical understanding of inferential statistics necessary for the statistical analysis of data from sensory tests. General issue: extract interpretable patterns from sensory measurements in order to make the right decisions.

The lessons will cover the requirements of each course, using relevant examples and applications.

Hourly volumes*:

            CM: 10 AM

            Practical work: 10 hours

See the full page

Polymers are used in a wide range of cosmetic formulations with various functions, the main ones being rheology control, formulation stabilization, and conditioning. It is therefore important to understand their behavior in these complex environments, particularly by studying polymer-surfactant interactions, since these two components are often present together in these environments, as well as interactions with solid surfaces (suspensions, applications on hair or skin) or liquids (emulsions).

The course describes: (1) the different types of polymers used: water-soluble, synthetic, natural and semi-natural, amphiphilic, and structure-property relationships; (2) the principle of thickening formulas or gelation using polymers; (3) interactions with surfactants, presentation of the different types of surfactants and their physicochemical properties, in particular polymeric surfactants, (4) interactions with surfaces (skin, hair) as well as any type of solid surface, (5) the principle of stabilizing emulsions and suspensions using polymers.

The second part of this module focuses on silicones and their use in cosmetics:

The chemistry of silicones, silicones for cosmetics: categories, uses, and sensory effects with examples of application.

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Basic knowledge of skin structure and physiology: skin structure; sensory receptors; mechanical and thermal sensitivity.

Skin penetration; skin hydration and moisturizing products; seborrhea, acne; types Dermocosmetics: skin penetration; skin aging, infant skin; cellulite

Hourly volumes:

            CM: 16

            TD: 4

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This module is devoted to the study of the main classes of cosmetic additives on the one hand, and to the study of natural, biotechnological, and synthetic active ingredients on the other.

The first part of this course will focus on marine flora, particularly the general composition and specific characteristics of different types of algae. What is the role and effectiveness of marine flora in cosmetics?

The course will conclude with case studies and perspectives.

The second part will focus on the plant world, enabling formulators and regulatory affairs managers to understand how plant molecules can be used to achieve beneficial effects in relation to the main cosmetic indications. Essential oils: what are the production techniques, chemical compositions, cosmetic properties, formulations, and safety profiles?

The third part of the module will focus on the different classes of additives used in cosmetics.

The focus will be on the chemical and organoleptic study of the main raw materials (synthetic or natural) used in the fragrance of cosmetics and the regulatory constraints related to their use (cosmetic directives relating to the dosage of allergens).

The families of odor molecules used in cosmetics (molecules without organic functions or containing alcohol, aldehyde, ketone, or ester functions) will be studied:
- molecules with an aromatic ring
- phenol-type molecules
- cyclic and acyclic aliphatic molecules.
- acyclic and cyclic terpene molecules
- field of odors.

-Concepts of molecular stability and volatility.

The course will conclude with training in the formulation of fragrance compositions for cosmetic products.

Hourly volumes:

            CM: 20

            TD: 10

            TP: 10

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What is eco-design? 

Product Life Cycle Assessment (LCA)
Who certifies?
Eco-design & raw materials
Biodiversity and the Nagoya Protocol.
Reminders on the principles of green chemistry
Ecotoxicology and biodegradability
Manufacturing an eco-designed cosmetic product
Trends related to eco-design

Eco-designed packaging: what is its impact?

Concept of ecotoxicology: impact on the environment/biodegradability

Information on eco-design measures: what tools are available/impact assessment Recyclability of packaging: measurement and analysis (raw materials/formulas/ecotoxicology).

Students will be given a scenario to work with.

Hourly volumes:

            CM: 20

            TD: 10

            TP: 10

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The EU's objective is to understand and apply the principles of color formulation as practiced in the color industry. To this end, the basics of spectrocolorimetry, light-matter interactions, and the simplest formulation models (Beer-Lambert and Kubelka-Munk) are studied and used in practical work.

Hourly volumes:

            CM: 12

            TP: 8

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Reminder of European legislation and its hierarchy: regulations, directives, decisions, resolutions, national laws, institutions, and authorities in charge of the regulatory system.

Description of key regulations around the world and overview of progress

Institutions and authorities responsible for the regulatory system

Regulatory framework applicable to cosmetic packaging

The process of ensuring cosmetic packaging compliance and its main challenges

New requirements applicable to cosmetic packaging under European and French circular economy laws

The course will cover Good Manufacturing Practices (GMP) designed to ensure the reproducibility and quality of cosmetic products.

It will enable you to identify the measures to be taken with regard to production, control, storage, and shipping processes and to ensure the compliance of cosmetic products with current regulations (EC 1223/2009, ISO 22716 standard, etc.).

Hourly volumes:

            CM: 15

            TD: 15

            Land: 10

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This module covers all aspects of photoprotection:

He will begin with a reminder about solar radiation and the skin, emphasizing natural melanin and non-melanin photoprotection. The skin's reaction to the sun will allow us to discuss the benefits of the sun, but will focus mainly on the harmful side effects for the skin. What protection options does the cosmetics industry offer? How can we analyze the effectiveness of sunscreen products? What is the impact of filters on the environment?

• Study of the development of sunscreen formulas: raw materials, chemical and physical filters, formulation techniques, regulations, the relationship between the sun and the skin.

• Use of software for calculating theoretical SPFs

• Acquire knowledge in the formulation of sunscreen products
• Manufacturing processes
• Detailed analysis of INCI formulas

• Phase inversion microemulsion formulation

Hourly volumes:

            CM: 15

            TP: 25

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This teaching unit covers several areas:

• The lessons will show that chemistry opens up a variety of careers in the cosmetics industry, not just in formulation.

• Know how to reflect on the scientific method in order to avoid errors in judgment and know how to apply scientific thinking to any information. Teaching will be based on concrete examples related to cosmetics (difference between risk and danger, reflection on various applications/consumer information, etc.).

• A simulation exercise allows students to work on concrete marketing projects, from market research to the formalization of a marketing concept in cosmetics.

Hourly volumes:

            CM: 12

            TD: 8

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In-depth study of different cosmetic formulations: composition, description of main components, formulation, principle, dosage forms

Study of ingredient families including emollients, esters, emulsifiers, sunscreens, preservatives, and innovations in skincare and makeup products.

Study of INCI lists of formulations, INCI nomenclatures

Study of different types of cosmetics companies

Study of manufacturing processes (agitation equipment, complementary manufacturing processes, impact of physical and chemical parameters on manufacturing)

The application will be implemented in various fields.

For example: formulation of moisturizing emulsions with electrolytes (stability disruptors), formulation of cleansing milk and cleansing lotion and implementation of tests to measure cleansing effectiveness, formulation of makeup products.

Hourly volumes:

            CM: 15

            TP: 25

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This module will enable students to understand the importance of innovation in a sector as dynamic as cosmetics.

This environment is governed by regulatory constraints, innovations in packaging, innovations in formulation, and also in ingredients.

The whole thing is also governed by the expectations of increasingly demanding consumers.

It is therefore essential for these future graduates to understand the ins and outs of innovation in cosmetics and to know how to implement it while respecting certain criteria.

A project will be proposed to students: Presentation of the project in groups and establishment of guidelines for its implementation.

Hourly volumes:

            CM: 20

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This 5- to 6-month internship, or work-study program, will take place in an R&D laboratory in the cosmetics and wellness industries.

The tasks assigned by the company to the intern/work-study student will be related to the objectives of the Master's degree.

This internship or work-study placement will take place in France or abroad.

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The objectives of the course are to explain the macroscopic behavior of systems through their microscopic description and to present the universal characteristics in the study of thermodynamic systems.

1. Thermodynamics reminders
2. A more general approach to statistical thermodynamics

III. Generalities on identical particle systems without interaction

1. Applications of Boltzmann statistics
2. An example of the use of another statistic: black body radiation.

Hourly volumes:

CM: 30

TD: 10

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NMR:

Liquid-phase NMR (Nuclear Magnetic Resonance) is an essential spectroscopic analysis method for chemists, enabling them to determine the structure of small organic molecules or macromolecules in solution, study dynamic phenomena, and more. The aim of this course unit is to understand the phenomena involved in this technique and to relate them to the various structural information accessible by this method. The goal is to be able to use the spectral data from this analysis to elucidate the structure and stereochemistry of organic molecules or polymer structures, or to monitor reactions.

X-ray diffraction:

X-ray diffraction is a powerful, non-destructive technique for characterizing the crystalline structure of materials. It can also provide crystallographic and structural information such as lattice parameters and atomic positions. This includes all crystallized materials such as ceramics, materials for energy and information storage and conversion, as well as organic molecules and metal complexes (interatomic distances and angles, stereochemistry (chirality, stereoisomerism, etc.), intra- and intermolecular bonds, etc.). The objective of this course unit is to provide an introduction to crystallography and diffraction, with the aim of understanding the operation and characteristics of an X-ray diffractometer, as well as interpreting diffraction patterns (structural analysis, lattice parameters).

Hourly volumes:

            CM: 10

            TD: 10

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The HAC720C module covers "advanced inorganic materials" in five main sections. The^first section is devoted to general information on inorganic materials and discusses structure-property relationships, with particular attention paid to chemical bonding, real crystals, and polycrystalline solids. The different classes of inorganic materials are described. The^second part focuses on ceramic materials (definitions and properties) and their synthesis (raw materials including clays, shaping, drying and debinding, sintering); a distinction is made between traditional ceramics and technical ceramics (synthesis methods for oxide and non-oxide ceramics). The^third part covers glass (classification and synthesis methods) and glass-ceramics (devitrification and soft chemistry); their properties and applications are also discussed. The^fourth part is dedicated to metals: properties of metals and metal alloys; metal nanoparticles; and catalytic materials. Part⁵ is devoted to inorganic materials developed for energy; ceramics (oxides and non-oxides; nanostructured) and metal hydrides are described (properties and synthesis) through several examples and in the context of their applications (accumulators, hydrogen storage, and carbon dioxide capture).

Hourly volumes:

CM: 1:00 p.m.

Tutorial: 7 hours

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- Review of thermodynamics of single-component systems.

- Basic concepts of thermodynamics in multicomponent systems. Chemical potential, Gibbs-Duhem relation, variance.

- Concepts related to thermal analysis techniques used to construct binary/ternary diagrams: ATG, ATD, and DSC

- Construction and interpretation of binary phase diagrams based on thermodynamic quantities. Gibbs free enthalpy, pressure, and temperature diagrams as a function of the composition of the binary mixture. Liquid-liquid, liquid-vapor, and solid-liquid mixtures.

- Phase transformations: first- and second-order transitions, critical points. Examples.

- The supercritical state: definition, thermodynamic properties, most widespread industrial applications.

- Construction and interpretation of ternary phase diagrams: variance, definitions of ternary eutectic, first and second order peritectic, isothermal section, study of alloy cooling.

Hourly volumes:

CM: 13

TD: 7

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This course will cover the fundamental concepts and practical tools related to chemometrics through: - statistical data analysis;

• the laws of probability;
• confidence interval estimation;
• parametric and nonparametric tests.

An introduction to design of experiments will be offered at the end of the module.

Hourly volumes:

CM: 7 a.m.

TD: 1:00 PM

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The first part of the course presents the fundamental knowledge of organometallic chemistry of transition metals. It begins with a description of the metal-carbon bond, enabling an understanding of its stability and chemical reactivity.  Next, we will demonstrate the power of this synthesis tool for forming C-H, C-C, and other bonds. Examples of their applications in different fields will help students learn about these reactions and their fields of application: fine chemistry, catalytic transformations of industrial importance, synthesis of natural products, and preparation of materials.

The second part of this course is devoted to the chemistry of heteroelements, focusing on silicon, tin, and boron. This part aims to present the different methods of preparing boron-, tin-, and silicon-based reagents, as well as the main transformations carried out with these compounds, with applications in organic synthesis and materials synthesis.

CM: 1:00 PM 

Tutorial: 7 hours

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The program of this EU focuses on describing the principles and applications of the main methods for the structural characterization of solids, thin films, surfaces, and interfaces, as well as several examples of applications in materials chemistry. It includes the following techniques.

• Introduction to solid-state NMR (NMR signal, interactions in solid-state NMR, magic angle spinning, NMR sequences, cross polarization, instrumentation, etc.)
• Electron microscopy: principles and applications of scanning and transmission electron microscopy and related techniques (EDS microanalysis).
• Spectroscopic methods: Raman spectroscopy, photoelectron spectroscopy, X-ray spectroscopy (XAS, XRF, etc.), Mössbauer spectrometry.

Hourly volumes:

            CM: 10 a.m.

            Tutorial: 10 a.m.

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This lecture, delivered entirely in English, provides a basic introduction to crystallography and electron diffraction for beginners. X-ray diffraction is an important characterization technique in modern chemistry; the majority of crystalline structures in inorganic and organic solids have been solved using this method. It is therefore important for all students to understand its basic concepts and instrumentation. The course provides explanations and principles of X-ray diffraction together with the geometry and symmetry of X-ray patterns. In addition to the interaction principles of X-rays and matter, it covers how to obtain quantitative intensities for single crystal and powder diffraction patterns. It naturally includes an understanding of lattice planes and the reciprocal lattice concept together with the Ewald sphere construction. Furthermore, it provides a basic understanding of the Fourier transform relationship between the crystalline structure and the diffracted intensities, as well as the reciprocal lattice concept.

Electron diffraction is a complementary technique to X-rays that provides information in terms of symmetry and geometry on the materials studied. In this course, we will therefore approach the description of the method for obtaining electron diffraction patterns and their interpretation. We will be able to obtain the lattice parameters, the reflection conditions, as well as the groups of possible spaces.

This lecture also serves as the introductory part to the lecture Electron Microscopy and Crystallography II.

CM: 14

TD: 6

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This teaching unit is dedicated to deepening the foundations of organic chemistry and coordination chemistry covered in L3 and to acquiring concepts related to molecular engineering and molecular chemistry. The teaching unit consists of lectures and tutorials. Students will prepare for certain lectures and tutorials using course materials provided, enabling them to participate fully in the lectures and tutorials, understand the concepts presented, and acquire the necessary skills. The progression program and activities will be proposed. For students who have not studied the basics of coordination chemistry and organic chemistry, documents will be made available.

Coordination chemistry: The course will cover various aspects of transition metal and lanthanide complexes, molecular materials (polynuclear complexes and coordination polymers with extended structures (MOFs, etc.)) as well as their properties and applications. Structural aspects, bond descriptions, properties, and aspects related to stability and reactivity will be addressed. Emphasis will be placed on the complexation effect and the stability of metal, lanthanide, and actinide complexes with certain ligands for applications in the biomedical field (imaging and therapy), decontamination (nuclear field), etc. The electronic (relaxivity, magnetism) and optical (absorption, luminescence) properties of these complexes will be discussed and placed in the context of applications in various fields, such as imaging, electronics, sensors, etc.

Organic Chemistry: The course builds on the knowledge acquired in the Bachelor's degree and will use a reasoned study approach to address the main reaction mechanisms in organic chemistry, providing a common foundation for all students in the Master's in Chemistry program. The main processes (substitution, addition, elimination, transposition, etc.) and their essential characteristics and applications to mechanistic sequences will be examined. This course should provide students with general tools for analyzing mechanisms (ionic, radical, concerted) in order to understand these mechanisms in all their variety.

Hourly volumes:

CM: 1:00 PM

Tutorial: 7 hours

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The professional project bridges the gap between traditional practical work and internships in laboratories or companies. It takes the form of a supervised project consisting of placing students in a professional situation through collaborative (group) work based on carrying out a project in response to a problem set by a company, local authority, association, or academic. It is part of the core curriculum of the Master's in Chemistry and is carried out under the supervision of a member of the teaching team (academic or industrial). Conducted throughout the semester, this project aims to connect and consolidate the knowledge and skills acquired during the Bachelor's and early Master's programs through this professional situation. These scenarios will be directly related to the Master's program chosen by the students. In addition to chemistry-specific skills, other interpersonal, organizational, and communication skills intrinsically linked to project management will also be acquired, equipping students for their future professional lives.

Addressing a research issue: example of a summary of new phosphorescent materials.

Hourly volumes:

CM: 5 hours

Tutorial: 5 hours

Practical work: 40 hours

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This teaching module aims to provide and understand the theoretical foundations associated with certain modeling methods found in various fields, from "small molecules" to living organisms and materials. This module seeks to answer, in part, three questions: 1) Why model? 2) What to model? 3) How to model?

Hourly volumes:

CM: 14

TP: 6

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A 2- to 4-month internship must be completed in a research or research and development laboratory specializing in theoretical chemistry. Students will have the opportunity to complete this internship in academic or private research laboratories. Subject to prior approval by the teaching team (internship topic related to the master's program and adequate environment/resources), students may seek a host team in an academic setting at the institutes of the Chemistry Department of the University of Montpellier, in academic laboratories outside the University of Montpellier (in France or abroad), or in the private sector (chemical, pharmaceutical, etc. industries).

This internship, lasting between two and four months, may begin in mid-May after the exam session and may not exceed four months.

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This course provides the theoretical basis for analyzing the microscopic origin of unusual physicochemical properties.

Crucial properties are addressed due to the intensity of research they generate and their technological applications: electron transfer, magnetism, photomagnetism, bistability, conduction, etc. Several types of compounds will be studied: molecular switches, mono- and multi-radical aromatic molecules and strategies for assembling ordered high-spin organic structures, spin transition compounds, magnetic molecules, and poly-metallic complexes coupled ferro-, antiferro- or ferrimagnetically.

1. Derivation of simple models for strongly correlated systems (Heisenberg).
2. Hydrocarbon compounds: aromaticity and magnetic properties of cyclic and polycyclic polyradical systems.
3. Monometallic complexes: spin transition compounds (crystal field and ligand field theories, concept of bistability). Magnetically anisotropic compounds (spin-orbit coupling), towards molecular magnets (hysteresis)...
4. Bimetallic complexes: electron transfer (molecular switches) in mixed-valence compounds and spin exchange in magnetic compounds (ferromagnetic and antiferromagnetic couplings), photomagnetism.

Hourly volumes:

CM: 24

TP: 8

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This course aims to deepen and supplement the theoretical knowledge acquired by students in spectroscopy during their bachelor's degree.

Hourly volumes:

CM: 15

TD: 9

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This EU will address, in small groups or on an individual basis, teaching tools and best practices related to communication and professional integration, through:

• assessment of knowledge, skills, competencies, interpersonal skills, and motivations;
• awareness of job search techniques;
• writing resumes and cover letters;
• rules for oral and written communication;
• job interview simulations.

Scenarios directly related to the sectors of activity targeted by the courses of the students concerned will be offered.

Practical work: 20 hours

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The electronic and optical properties of solids are central to many applications in the fields of energy (photovoltaic panels, passive coolants, etc.), light production (white diodes, lasers, etc.), and electronics (components, microprocessors, etc.). After an introduction to these different fields of application, this course aims to define the various concepts necessary for mastering both the electronic and optical properties of materials, which are essential for understanding the most modern technologies.

Hourly volumes:

            CM: 11 a.m.

            TD: 9 a.m.

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A general approach to the coordination chemistry of f-elements will be developed through the concepts of atomistics, oxidation state, and coordination polyhedra in order to highlight the specific characteristics of f-elements. Direct comparisons will be made with the coordination chemistry of transition elements, and applications related to nuclear chemistry will be discussed.

Hourly volumes:

            CM: 12 p.m.

            Tutorial: 8 hours

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Examples of homogeneous catalysis reactions will be presented, emphasizing the underlying concepts and limitations of theoretical approaches (mainly DFT). Olefin metathesis and examples of polymerization will illustrate supported catalysis, emphasizing the influence of the support.

Various examples will illustrate the specificity of nanocatalysts, distinguishing between the respective roles of electronic and geometric factors.

Hourly volumes:

CM: 20

TD: 10

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The objective is to acquire strong skills in theoretical chemistry by discovering or exploring various topics in depth.

This module is organized in two phases: (i) online seminars, delivered throughout the first semester; (ii) a week of intensive training at the beginning of January, at one of the sites of the South-West cluster of the French Network for Theoretical Chemistry (Bordeaux, Montpellier, Pau, Toulouse).

The topics covered are:

– quantum chemistry and relativity

– Monte Carlo methods

– exploration of potential energy surfaces

– calculation of the electronic structure of periodic systems

– quantum dynamics

– calculation of spectroscopic properties

Hourly volumes:

CM: 40

TD: 20

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This module prepares students for doctoral studies in theoretical chemistry, particularly in the field of quantum chemistry. Recent methodological advances and the development of increasingly powerful software have democratized the use of quantum chemistry software.

The module covers topics in the fields of electronic structure and molecular dynamics. The formalism of the various methods and their areas of application will be explained in detail to enable informed use of theoretical chemistry software, particularly quantum chemistry software.

(1) electronic structure

– Hartree-Fock

– electronic correlation, configuration interaction, coupled cluster

– Density Functional Theory (DFT)

(2) nuclear dynamics

– Classical and ab initio dynamics (Car Parrinello, Born-Oppenheimer, propagators, thermodynamic ensembles, free energy calculation)

– quantum dynamics of photo-induced processes (wave packet, adiabatic and non-adiabatic dynamics, link with the absorption spectrum, diabatic representation, mixed classical-quantum dynamics)

Hourly volumes:

CM: 10

TD: 20

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Present methods for exploring the physical and chemical properties of materials through numerical calculation. Provide the mathematical foundations for the numerical tools presented in the "Modeling" course in the first year of the Master's program and supplement the applications covered in that course.

Hourly volumes:

CM: 28

TD: 12

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During this course, students will learn about the main numerical methods used in scientific software, particularly in theoretical chemistry programs.

Hourly volumes:

CM: 21

TD: 9

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Present methods that enable the physical and chemical properties of materials to be explored through numerical calculation. Provide the mathematical foundations of the associated numerical tools.

I- Introduction

II- Quantum approach: molecular methods: Quantum mechanics, Schrödinger equation, DFT methods.

III- Quantum approach: periodic systems

IV- Molecular dynamics: classical approach

Hourly volumes:

CM: 30

TD: 10

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A 5- to 6-month internship must be completed in a research or research and development laboratory specializing in theoretical chemistry. Students will therefore have the opportunity to complete this end-of-study internship in academic or private research laboratories. Subject to prior approval by the teaching team (internship topic related to the master's program and adequate environment/resources), students may seek a host team in an academic setting at the institutes of the Chemistry Department of the University of Montpellier, in academic laboratories outside the University of Montpellier (in France or abroad), or in the private sector (chemical, pharmaceutical, etc.).

This internship, lasting 5 to 6 months, may begin in mid-January after the exam session and may not exceed 6 months for a period including semester 10 during the validity of university enrollment.

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Fluorinated biomolecules. Current developments in fluorinated molecules. Fluorination methods: nucleophilic and electrophilic monofluorination, introduction of difluoromethyl or trifluoromethyl groups. Contribution of fluorine atoms to the activity of these compounds. Examples of syntheses of fluorinated compounds used as antitumor agents, antivirals, antidepressants, anxiolytics, anti-inflammatories, etc.

Phosphorus-containing biomolecules. Structure, nomenclature, reactivity, structural analysis, and applications.

Several methods for synthesizing compounds from each of the families covered will be discussed, highlighting unconventional activation methods where applicable. Biomedical applications will be targeted, as well as other applications in agrochemistry, optoelectronics, nanomaterials, etc.

Hourly volumes:

CM: 15 hours (7.5 hours fluorinated biomolecules and 7.5 hours phosphorous biomolecules)

Tutorial: 5 hours

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This course unit enables students to acquire basic knowledge and cross-disciplinary skills in the field of colloids and interfaces, which are common to the various tracks of the Master's degree in Chemistry (Materials Chemistry, Separative Chemistry, Materials and Processes, ICAP Cosmetics Engineering, Biomolecular Chemistry). It is also offered to international students enrolled in the SFRI program at the University of Montpellier, where courses are taught in English. An introductory presentation on basic notions and concepts will enable students to discover and better understand the main physicochemical properties of colloidal dispersions, associative colloids, and macromolecular solutions, as well as the parameters and phenomena governing stability in colloidal dispersions and mixed solution-colloid systems. This will be followed by interdisciplinary practical teaching based on the flipped classroom principle to help students build and deepen their knowledge through individual and collective analysis of the various applications of colloidal and interfacial phenomena and systems.

Hourly volumes:

CM: 7

TD: 13

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This course aims to teach liquid chromatography and gas chromatography.

Hourly volumes:

            CM: 3:00 p.m.

            Tutorial: 5 hours

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Knowledge of gas chromatography techniques and mass spectrometry with electron impact ionization and quadrupole mass analyzer for the analysis of volatile organic molecules.

1) GC-MS analyses of volatile organic compounds:

• Electron impact (EI) ionization techniques
• Chemical ionization (CI) techniques
• Quadrupole (Q) analysis techniques
• GC/MS Couplings

2) Applications in organic chemistry analysis and characterization of volatile samples.

Hourly volumes*:

CM: 3 p.m.

Tutorial: 5 hours

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Knowledge of the major families of polymers used in the biomedical field.

1) Specificity of polymers for biomedical applications and major families of polymers used

2) Description of application families

3) Discussion on the concept of synthesis and the relationship between structure, properties, and specifications

Hourly volumes*:

CM: 3 p.m.

Tutorial: 5 hours

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This course concisely and systematically covers all aspects of heterocyclic chemistry, from nomenclature to applications such as the principles of action of medicines, toxins, drugs, pigments, food colorings, etc.

Hourly volumes*:

CM: 3 p.m.

Tutorial: 5 hours

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Natural products occupy a major place in the field of biomolecular chemistry. They represent an important source of bioactive compounds for medicinal chemistry. This teaching unit provides a comprehensive overview of secondary metabolism and the origin of natural products derived from plants. This teaching unit will focus on the organic chemistry behind the various biotransformations that occur during the biosynthesis of each major class of molecule. A mechanistic approach will be used to understand the chemical basis of each transformation.

Hourly volumes*:

CM: 13 

TD: 7

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NMR:

Liquid-phase NMR (Nuclear Magnetic Resonance) is an essential spectroscopic analysis method for chemists, enabling them to determine the structure of small organic molecules or macromolecules in solution, study dynamic phenomena, and more. The aim of this course unit is to understand the phenomena involved in this technique and to relate them to the various structural information accessible by this method. The goal is to be able to use the spectral data from this analysis to elucidate the structure and stereochemistry of organic molecules or polymer structures, or to monitor reactions.

X-ray diffraction:

X-ray diffraction is a powerful, non-destructive technique for characterizing the crystalline structure of materials. It can also provide crystallographic and structural information such as lattice parameters and atomic positions. This includes all crystallized materials such as ceramics, materials for energy and information storage and conversion, as well as organic molecules and metal complexes (interatomic distances and angles, stereochemistry (chirality, stereoisomerism, etc.), intra- and intermolecular bonds, etc.). The objective of this course unit is to provide an introduction to crystallography and diffraction, with the aim of understanding the operation and characteristics of an X-ray diffractometer, as well as interpreting diffraction patterns (structural analysis, lattice parameters).

Hourly volumes:

            CM: 10

            TD: 10

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Knowledge of the latest mass spectrometry techniques for the qualitative analysis of organic molecules and biomolecules.

1) Description of fundamental principles (Ion science and technology):

- Ionization techniques

- Analysis techniques

- Tandem mass spectrometry (MS/MS)

- LC/MS and LC/MS/MS couplings

2) Application in the context of biomolecule analysis and monitoring of organic chemistry reactions.

Hourly volumes*:

CM: 3 p.m.

Tutorial: 5 hours

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This course will cover the fundamental concepts and practical tools related to chemometrics through: - statistical data analysis;

• the laws of probability;
• confidence interval estimation;
• parametric and nonparametric tests.

An introduction to design of experiments will be offered at the end of the module.

Hourly volumes:

CM: 7 a.m.

TD: 1:00 PM

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The first part of the course presents the fundamental knowledge of organometallic chemistry of transition metals. It begins with a description of the metal-carbon bond, enabling an understanding of its stability and chemical reactivity.  Next, we will demonstrate the power of this synthesis tool for forming C-H, C-C, and other bonds. Examples of their applications in different fields will help students learn about these reactions and their fields of application: fine chemistry, catalytic transformations of industrial importance, synthesis of natural products, and preparation of materials.

The second part of this course is devoted to the chemistry of heteroelements, focusing on silicon, tin, and boron. This part aims to present the different methods of preparing boron-, tin-, and silicon-based reagents, as well as the main transformations carried out with these compounds, with applications in organic synthesis and materials synthesis.

CM: 1:00 PM 

Tutorial: 7 hours

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This teaching unit is dedicated to deepening the foundations of organic chemistry and coordination chemistry covered in L3 and to acquiring concepts related to molecular engineering and molecular chemistry. The teaching unit consists of lectures and tutorials. Students will prepare for certain lectures and tutorials using course materials provided, enabling them to participate fully in the lectures and tutorials, understand the concepts presented, and acquire the necessary skills. The progression program and activities will be proposed. For students who have not studied the basics of coordination chemistry and organic chemistry, documents will be made available.

Coordination chemistry: The course will cover various aspects of transition metal and lanthanide complexes, molecular materials (polynuclear complexes and coordination polymers with extended structures (MOFs, etc.)) as well as their properties and applications. Structural aspects, bond descriptions, properties, and aspects related to stability and reactivity will be addressed. Emphasis will be placed on the complexation effect and the stability of metal, lanthanide, and actinide complexes with certain ligands for applications in the biomedical field (imaging and therapy), decontamination (nuclear field), etc. The electronic (relaxivity, magnetism) and optical (absorption, luminescence) properties of these complexes will be discussed and placed in the context of applications in various fields, such as imaging, electronics, sensors, etc.

Organic Chemistry: The course builds on the knowledge acquired in the Bachelor's degree and will use a reasoned study approach to address the main reaction mechanisms in organic chemistry, providing a common foundation for all students in the Master's in Chemistry program. The main processes (substitution, addition, elimination, transposition, etc.) and their essential characteristics and applications to mechanistic sequences will be examined. This course should provide students with general tools for analyzing mechanisms (ionic, radical, concerted) in order to understand these mechanisms in all their variety.

Hourly volumes:

CM: 1:00 PM

Tutorial: 7 hours

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The professional project bridges the gap between traditional practical work and internships in laboratories or companies. It takes the form of a supervised project consisting of placing students in a professional situation through collaborative (group) work based on carrying out a project in response to a problem set by a company, local authority, association, or academic. It is part of the core curriculum of the Master's in Chemistry and is carried out under the supervision of a member of the teaching team (academic or industrial). Conducted throughout the semester, this project aims to connect and consolidate the knowledge and skills acquired during the Bachelor's and early Master's programs through this professional situation. These scenarios will be directly related to the Master's program chosen by the students. In addition to chemistry-specific skills, other interpersonal, organizational, and communication skills intrinsically linked to project management will also be acquired, equipping students for their future professional lives.

Addressing a research issue: example of a summary of new phosphorescent materials.

Hourly volumes:

CM: 5 hours

Tutorial: 5 hours

Practical work: 40 hours

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The internship in semester 8 of the Master 1 in Biomolecular Chemistry aims to familiarize students with careers in life sciences research. Students will have the opportunity to complete this introductory research internship in academic or private laboratories. Subject to prior approval by the teaching team (internship topic related to the Master's program and appropriate environment/resources), students may seek a host team in an academic setting at one of the institutes of the Chemistry Cluster at the University of Montpellier (IBMM, ICGM, , etc.), in academic laboratories outside the University of Montpellier (in France or abroad), or in the private sector (chemical, pharmaceutical, and agri-food industries, biotechnology laboratories, etc.).

Fieldwork: 2 to 4 months of internship

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Nucleosides are the basic building blocks of nucleic acids (DNA and RNA). As such, they play an essential role in many biological processes. This course will present the structure and biological role of natural nucleosides. The main methods of synthesis and characterization of these compounds and their analogues (glycosylation reactions, structural modifications of the furanose ring, substitution and introduction of heteroatoms, configuration inversion, etc.) will also be discussed. The use of nucleoside analogues for the treatment of viral diseases and cancers will also be addressed.

Hourly volumes:

CM: 3 p.m.

Tutorial: 5 hours

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This teaching unit is shared by MI students in the Master's in Chemistry program: ICAP P1, ICAP P2, MAT P1, MAT P2, and BM (semester S2) courses. The following topics will be covered:

• The 12 Principles of Green Chemistry and units of measurement in Green Chemistry;
• Synthesis strategies in sustainable chemistry;
• Alternative or eco-friendly solvents for synthesis and extraction;
• Unconventional activation techniques and applications.

CM: 13

Tutorial: 7 hours

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The aim of teaching medicinal chemistry is to introduce students to the key stages in the process of developing molecules with biological activities. In particular, a description of the interactions involved, the concept of pharmacophores, bioisosterism, etc., as well as structure-activity relationship studies will be covered, enabling students to consider appropriate strategies and structural modifications.

Hourly volumes:

CM: 3 p.m.

Tutorial: 5 hours

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After covering the basics of prochirality and stereochemistry, this course will introduce the tools needed to master diastereoselective and enantioselective synthesis. The various approaches will be presented in a detailed and rational manner. Examples of industrial synthesis of chiral bioactive molecules will be discussed.

Hourly volumes*:

CM: 3 p.m.

Tutorial: 5 hours

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This course covers synthesis methods applied to obtaining enantiopure amino acids, as well as the use of chiral amino acids for the synthesis of other enantiopure compounds.

These amino acids are the basic building blocks of peptides. The different physicochemical properties induced by the nature of these amino acids will enable the definition of strategies for synthesizing peptides of interest and their characterization.

Hourly volumes*:

CM: 3 p.m.

Tutorial: 5 hours

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The following topics will be covered:

- Bio-based solvents

- Fuels derived from biomass

- Antioxidants derived from lignin

- Metal catalysts derived from plants

- Surfactants obtained from renewable resources

- Examples of industrial applications of enzymatic synthesis

Hourly volumes*:

CM: 15

TD: 5

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This EU will address, in small groups or on an individual basis, teaching tools and best practices related to communication and professional integration, through:

• assessment of knowledge, skills, competencies, interpersonal skills, and motivations;
• awareness of job search techniques;
• writing resumes and cover letters;
• rules for oral and written communication;
• job interview simulations.

Scenarios directly related to the sectors of activity targeted by the courses of the students concerned will be offered.

Practical work: 20 hours

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