Targeted Delivery

This course covers the various molecular and supramolecular tools used for the vectorization and delivery of active ingredients based on the type of cells or intracellular organelles being targeted. Ligand-receptor interactions will be discussed, as will methods for preparing and activating conjugates. Examples of drugs will be presented.

Hourly Volumes*:

CM: 3:00 p.m.

TD: 5 H

: Understand the molecular or supramolecular tools used for the vectorization and targeted delivery of active ingredients.

Biomolecular Chemistry (M1 Level)

Some Basics of Cell Biology

2-hour final written exam:

• Authorized documents: No
• Non-graphical calculators allowed: yes
• Internet access allowed: No

Course:

• non-viral gene therapy (lipoplexes, polyplexes);
• targeted nanoparticles (PMO, MSN, silicon, etc., for single-photon or two-photon PDT, or cancer therapy; EPR effect);
• targeted therapeutic liposomes;
• transport of active ingredients by cyclodextrins;
• the use of antibody-drug conjugates (ADCs) for the treatment of certain cancers;
• lysosome targeting (LYTAC) for the degradation of pathogenic molecules.

TD: Review of Publications

Administrative contact(s):

Master's in Chemistry Office

https://master-chimie.edu.umontpellier.fr/