Organometallic and hetero-element chemistry

The first part of the course introduces the fundamentals of transition metal organometallic chemistry. It begins with a description of the Metal-C bond, enabling us to understand its stability and chemical reactivity. Secondly, the power of this synthesis tool for the formation of C-H, C-C, etc. bonds will be demonstrated. Examples of their applications in various fields will enable the acquisition of these reactions and their fields of application: fine chemistry, catalytic transformations of industrial importance, synthesis of natural products, preparation of materials.

The second part of this course is dedicated to hetero-element chemistry, focusing on the elements Silicon, Tin and Boron. The aim of this part is to present the various methods for preparing boron-, tin- and silicon-based reagents, as well as the main transformations carried out with these compounds, with applications in organic synthesis and materials synthesis.

CM: 13 H 

TD: 7 H

Organometallic and hetero-element chemistry offers unique synthesis tools, which are used in a wide range of fields: active ingredient synthesis, total synthesis, catalysis, molecular and macromolecular materials. The aim of the course is to provide the initial knowledge needed to understand and acquire the basic concepts of this chemistry.

Knowledge of molecular chemistry at Licence L3 level: good knowledge of organic chemistry, the structure of matter, the nature of bonds and their reactivity.

Final written exam, 2 hours:

• Authorized documents: no
• Non-graphic calculator allowed: yes
• Internet allowed: no

Classes: 1 p.m.

Organometallic chemistry:

Structure/reactivity relationships of catalysts for metal-catalyzed reactions ;

Influence of the nature of ligands on catalytic reaction processes ; 

Metallocatalyzed reactions as tools in synthesis and synthesis strategy ;

Sustainable development chemistry

Plan :

I - Introduction

II - Metal-ligand bonds

III - Counting valence electrons (16/18 electron rule)

IV - Elementary reactions

V - Attack on ligands

VI - Catalysis

Hydrogenation of alkenes

Alkene polymerization

Olefin metathesis

Coupling reaction

Hetero-element chemistry :

1. Tin compounds

General

Reactivity in organic synthesis

1. Silicon compounds

General

Reactivity in organic synthesis

1. Boron compounds

General

Reactivity in organic synthesis

TD: 7H

Individual work, exercises to prepare before and during the session.

On both parts, application exercises (and their correction) will be drawn from recent literature and past exam subjects.

Knowledge of coordination chemistry at Licence L3 level: knowledge of complex structure, complexation reactions, nature and properties of ligands.