Organometallic chemistry and heteroelement chemistry

The first part of the course presents the fundamental knowledge of organometallic chemistry of transition metals. It begins with a description of the metal-carbon bond, enabling an understanding of its stability and chemical reactivity.  Next, we will demonstrate the power of this synthesis tool for forming C-H, C-C, and other bonds. Examples of their applications in different fields will help students learn about these reactions and their fields of application: fine chemistry, catalytic transformations of industrial importance, synthesis of natural products, and preparation of materials.

The second part of this course is devoted to the chemistry of heteroelements, focusing on silicon, tin, and boron. This part aims to present the different methods of preparing boron-, tin-, and silicon-based reagents, as well as the main transformations carried out with these compounds, with applications in organic synthesis and materials synthesis.

CM: 1:00 PM 

Tutorial: 7 hours

Organometallic and heteroelement chemistry offers unique synthesis tools whose wide range of applications demonstrates their importance: synthesis of active ingredients, total synthesis, catalysis, molecular and macromolecular materials. The course aims to provide the initial knowledge needed to understand and acquire the basic concepts of this chemistry.

Knowledge of molecular chemistry at Bachelor's degree level: good knowledge of organic chemistry, the structure of matter, the nature of bonds, and their reactivity.

2-hour final written exam:

• Authorized documents: no
• Non-graphing calculator permitted: yes
• Internet access: no

Class: 1:00 p.m.

Organometallic chemistry:

Structure/reactivity relationships of metal-catalyzed reaction catalysts;

Influence of ligand nature on catalytic reaction processes; 

Metal-catalyzed reactions as tools in synthesis and synthesis strategy;

Chemistry for sustainable development

Map:

I - Introduction

II - Metal-ligand bonds

III - Counting valence electrons (16/18 electron rule)

IV - Elementary reactions

V - Attack on ligands

VI – Catalysis

Hydrogenation of alkenes

Polymerization of alkenes

Olefin metathesis

Coupling reaction

Chemistry of heteroelements:

1. Tin compounds

General information

Reactivity in organic synthesis

1. Silicon Compounds

General information

Reactivity in organic synthesis

1. Boron compounds

General information

Reactivity in organic synthesis

Tutorial: 7 hours

Individual work, exercises to be prepared before and during the session.

Both parts of the application exercises (and their corrections) will be drawn from recent literature and past exam questions.

Knowledge of coordination chemistry at Bachelor's degree level: knowledge of complex structures, complexation reactions, nature and properties of ligands.