Heterocyclic chemistry

This course concisely and systematically covers all aspects of heterocyclic chemistry, from nomenclature to applications such as the principles of action of medicines, toxins, drugs, pigments, food colorings, etc.

Hourly volumes*:

CM: 3 p.m.

Tutorial: 5 hours

Become familiar with the nomenclature of heterocyclic compounds and their synthesis.

Explore conventional methods for obtaining common nitrogen, oxygen, and sulfur heterocycles.

Be able to propose access routes enabling the synthesis of heterocyclic molecules.

Organic Chemistry, Level L3

2-hour final written exam

Authorized documents: no

Non-graphing calculator permitted: yes

Internet access: no

Classes: 15 hours

The chemistry and retrosynthesis of each major heterocyclic family (pyridines, diazines, quinolines, pyrroles, indoles, furans, thiophenes, azoles, purines, and pteridines) are addressed systematically. The areas of application for each family of heterocycles are illustrated through concrete examples (active ingredients, drugs, flavorings, pigments, etc.).

1. Nomenclature of heterocycles
2. General methods for synthesizing cycles with 3, 4, 5, and 6 atoms
3. Palladium-catalyzed reactions in heterocyclic chemistry
4. Heterocycles containing more than two heteroatoms

Tutorial:5 hours

Tutorials allow students to illustrate and apply the concepts developed in class through exercises focusing on nomenclature, synthesis, retro-synthetic analysis, and the reactivity of aromatic heterocycles, concentrating mainly on 5- and 6-membered rings. 

Teaching staff:

Michael Smietana,

Michael Smietana@montpellier.fr

Jean-Pierre Uttaro

Jean-pierre.uttaro@umontpellier.fr