Heterocyclic Chemistry

This course provides a concise and systematic overview of all aspects of heterocyclic chemistry, from nomenclature to applications such as the mechanisms of action of medications, toxins, and drugs, as well as pigments, food colorings, and more…

Hourly Volumes*:

CM: 3:00 p.m.

TD: 5 hours

Become familiar with the nomenclature of heterocyclic compounds and their synthesis.

Explore the conventional methods for synthesizing common nitrogen-, oxygen-, and sulfur-containing heterocycles.

Be able to propose synthetic routes for the synthesis of heterocyclic molecules.

Organic Chemistry, L3 Level

2-hour final written exam

Authorized documents: No

Non-graphical calculators allowed: yes

Internet access allowed: No

Class: 15 hours

The chemistry and retrosynthesis of each major family of heterocycles (pyridines, diazines, quinolines, pyrroles, indoles, furans, thiophenes, azoles, purines, and pteridines) are covered systematically. The areas of application for each family of heterocycles are illustrated through concrete examples (active ingredients, drugs, flavorings, pigments, etc.).

1. Nomenclature of Heterocycles
2. General Methods for the Synthesis of Rings with 3, 4, 5, and 6 Atoms
3. Palladium-Catalyzed Reactions in Heterocyclic Chemistry
4. Heterocycles containing more than two heteroatoms

TD:5H

The tutorials provide an opportunity to illustrate and apply the concepts covered in class through exercises on nomenclature, synthesis, retrosynthetic analysis, and the reactivity of aromatic heterocycles, with a primary focus on 5- and 6-membered rings. 

Teaching staff:

Michael Smietana,

Michael.smietana@umontpellier.fr

Jean-Pierre Uttaro

Jean-pierre.uttaro@umontpellier.fr