Heterocyclic chemistry

This course deals concisely and systematically with all aspects of heterocycle chemistry, from nomenclature to applications such as the principles of action of medicines, toxins or drugs, pigments, food colorants etc...

Hourly volumes* :

CM: 15 H

TD: 5 H

Familiarize yourself with the nomenclature of heterocyclic compounds and their synthesis.

Explore conventional methods for obtaining common nitrogen, oxygen and sulfur heterocycles.

Be able to propose access routes for the synthesis of heterocyclic molecules.

Organic Chemistry, L3 level

2-hour final written exam

Authorized documents: no

Non-graphic calculator allowed: yes

Internet allowed: no

Classes: 3 p.m.

The chemistry and retro-synthesis of each major heterocycle family (pyridines, diazines, quinolines, pyrroles, indoles, furans, thiophenes, azoles, purines and pteridines) are systematically covered. The fields of application of each heterocycle family are illustrated with concrete examples (active ingredients, drugs, flavors, pigments, etc.).

1. Heterocycle nomenclature
2. General methods for 3-, 4-, 5- and 6-atom ring synthesis
3. Pallado-catalyzed reactions in heterocyclic chemistry
4. Heterocycles with more than two heteroatoms

TD :5H

Tutorials illustrate and apply the concepts developed in class through exercises on the nomenclature, synthesis, retro-synthetic analysis and reactivity of aromatic heterocycles, focusing primarily on 5- and 6-membered rings. 

Teaching team:

Michael Smietana,

Michael.smietana (Michael.smietana @ umontpellier.fr)@ (Michael.smietana @ umontpellier.fr)umontpellier.fr (Michael.smietana @ umontpellier.fr)

Jean-Pierre Uttaro

Jean-pierre.uttaro@umontpellier.fr