Multistep synthesis

This course aims to describe the synthetic tools applied to complex and polyfunctional molecules. Retrosynthetic and stereocontrolled approaches will be covered, as well as the judicious use of protective groups.

Hourly Volumes*:

CM: 9:00 a.m.

Land: 11 H

Be able to propose several synthesis strategies for target molecules and justify one's choices. 

Advanced Organic Chemistry; Reaction Mechanisms

2-hour final written exam:

• Authorized documents: No
• Non-graphical calculators allowed: yes
• Internet access allowed: No

Courses: Retrosynthetic analysis; multistep syntheses; stereocontrolled syntheses; protective groups; literature review.

Lab Sessions: The multi-step syntheses studied in lab sessions will be based on both a theoretical understanding of the reactions involved and knowledge of the appropriate procedures to be followed. Time management, experiment planning, the organization of experimental synthesis techniques (extraction, distillation, recrystallization, chromatography), and methods for characterizing the resulting organic compounds will be necessary to successfully complete these syntheses. The skills students will acquire during these lab sessions are:

• Conduct an experimental protocol in French or English in accordance with good laboratory practices.
• Work independently and with others.
• Analyze and interpret the results obtained.
• Write a report describing the procedures performed, the characterization of the products obtained, and the analyses of those products.
• Present the work that has been done.

Teaching Staff :

Emmanuelle Rémond

Caroline Clavel

Administrative contact(s):

Master's in Chemistry Office

https://master-chimie.edu.umontpellier.fr/