Green chemistry

The principles of green chemistry provide a basis for evaluating and designing new chemical products and processes that minimize negative impacts on human health and the environment. In this teaching unit, offered to M2 students in the Master's program in Biomolecular Chemistry (BM), Orientation 2 (O2), the basic principles and concepts of green chemistry will be addressed, along with their applications in the field of unconventional activation methods and the use of alternative media in organic synthesis.

Hourly volumes*:

CM: 9 a.m.

Field: 11 a.m.

The objective of this course unit is to deepen and broaden students' theoretical and practical knowledge in the field of green chemistry, particularly in the area of activation methods and alternative media. At the end of this course unit, students will be able to: 1-implement an organic synthesis process taking into account the principles of green chemistry; 2- use unconventional activation methods in organic chemistry; 3- adapt their synthesis strategy by using alternative solvents (water) or carry out solvent-free reactions; 4- use sonochemistry and mechanochemistry equipment.

Organic chemistry, M1 level

Knowledge of the basic principles of green chemistry and activation techniques in green chemistry.

1.5-hour written final exam

Course:

1. The 12 principles of Green Chemistry and units of measurement ( review, bibliographic resources posted on Moodle + 1.5 hours); Case studies and industrial applications in drug preparation
2. Organic sonochemistry and mechanochemistry ( 4.5 hours):

• Mechanochemistry applied to the synthesis of biomolecules and pharmaceutical active ingredients;
• Organic sonochemistry: synthesis of high value-added molecules;

1. Organic synthesis strategies in unconventional environments (3 hours)

• Chemistry in water;
• Phase transfer catalysis;

Fieldwork (11 hours): Working in pairs, preparing biomolecules using sonochemistry and mechanochemistry

Teaching staff :

Jean-Yves Winum

jean-yves.winum@umontpellier.fr

Evelina Colacino

evelina.colacino@umontpellier.fr

Administrative contact(s):

Master's Program in Chemistry Secretariat

https://master-chimie.edu.umontpellier.fr/