Green chemistry

The principles of Green Chemistry provide a basis for the evaluation and design of new chemical products and processes that minimize negative impacts on human health and the environment. In this teaching unit, offered to M2 students of the Master of Biomolecular Chemistry (BM), Orientation 2 (O2), the basic principles and concepts of Green Chemistry will be discussed, and their applications in the field of non-conventional activation methods and the use of alternative media in organic synthesis.

Hourly volumes* :

CM : 9 H

Field: 11 a.m.

The objective of this course is to deepen and extend the theoretical and practical knowledge of the student in the field of green chemistry and more particularly in the field of activation methods and alternative media. At the end of this course, the student will be able to: 1 - implement an organic synthesis process taking into account the principles of green chemistry; 2 - use non-conventional activation methods in organic chemistry; 3 - adapt his or her synthesis strategy by using alternative solvents (water) or carry out solvent-free reactions; 4 - use sonochemical and mechanochemical equipment.

Organic chemistry level M1

Knowledge of the basic principles of green chemistry and green chemistry activation techniques.

Final written exam of 1h30

Course:

1. The 12 principles of Green Chemistry and units of measurement (review, bibliographic resources on Moodle + 1.5 h); Case studies and industrial applications in drug preparation
2. Organic Sonochemistry and Mechanochemistry (4.5 h):

• Mechanochemistry applied to the synthesis of biomolecules and pharmaceutical actives;
• Organic sonochemistry: synthesis of molecules with high added value;

1. Organic synthesis strategies in non-conventional environments (3 h)

• Chemistry in water;
• Phase transfer catalysis;

Fieldwork (11H ): Pair work, preparation of biomolecules, sonochemistry and mechanochemistry

Teaching team :

Jean-Yves Winum

jean-yves.winum@umontpellier.fr

Evelina Colacino

evelina.colacino@umontpellier.fr

Administrative contact(s):

Secretariat Master Chemistry

https://master-chimie.edu.umontpellier.fr/