Coordination and organic chemistry

This teaching unit is dedicated to deepening the foundations of organic chemistry and coordination chemistry covered in L3, and acquiring notions linked to molecular engineering and molecular chemistry. The course comprises lectures and tutorials. Students will work in advance of certain lectures and tutorials, with course documents provided, to ensure that the lectures and tutorials enable them to play a full part in the course, understand the concepts presented and the skills to be acquired. A progression program and activities will be proposed. For students who have not seen the basics of coordination chemistry and organic chemistry, documents will be made available.

Coordination chemistry: The course will cover various aspects of transition metal and lanthanide complexes, molecular materials (polynuclear complexes and coordination polymers with extended structures (MOFs, etc.)), their properties and applications. Structural aspects, bonding description, properties, as well as stability and reactivity aspects will be covered. Emphasis will be placed on the complexation effect and stability of metal, lanthanide and actinide complexes with certain ligands, with a view to applications in the biomedical field (imaging and therapy), decontamination (nuclear field), etc. The electronic (relaxivity, magnetism) and optical (absorption, luminescence) properties of these complexes will be discussed and put into the context of applications in various fields, such as imaging, electronics, sensors, etc.

Organic Chemistry: This course builds on the knowledge acquired in the Bachelor's degree, and will involve a reasoned study of the main reaction mechanisms in organic chemistry, providing a common foundation for all students in the Chemistry Master's program. The main processes (substitution, addition, elimination, transposition...) and their essential characteristics and applications to mechanistic sequences will be examined. The course is designed to provide students with general tools for analyzing mechanisms (ionic, radical, concerted) in order to grasp their variety.

Hourly volumes* :

CM: 13 H

TD: 7 H

The objectives of this course are to provide the theoretical and practical knowledge and skills in organic chemistry and coordination chemistry that are essential for students on a Master's degree in Chemistry, whatever their chosen path:

- Know and master modern concepts of coordination chemistry: know how to write formulas, know how to discuss structural aspects of coordination compounds (mononuclear, polynuclear complexes and molecular materials), know how to describe bonding and interpret electronic properties (magnetic, optical, insertion), know the concept of complex stability from a thermodynamic and reactivity point of view. Knowledge of the main applications of coordination complexes and molecular materials.

- Know and master the main reaction mechanisms in molecular and organic chemistry: know how to write mechanisms and give the geometry of reaction intermediates, analyze a reaction mechanism.

L3 Inorganic chemistry, coordination chemistry

L3 Organic chemistry

Reactivity basics

Final written exam 2h

• Authorized documents: no
• Non-graphic calculator allowed: yes
• Internet allowed: no

Course: Inductive (problem-based) and deductive teaching methods, Support(s) available on ENT (Moodle): Course documents, TD documents, Moodle activities with corrections. Examination books and reference publications available.

Coordination chemistry.

1. Introduction: History of coordination chemistry and applications of coordination compounds and materials.
2. Notions, definitions, fields of coordination chemistry. Isomerism
3. Ligands in coordination chemistry.
4. Description of the bond in coordination chemistry.
5. Electronic properties (magnetic, optical and luminescence properties). Applications
6. Molecular engineering. Polynuclear complexes. Properties and applications
7. Molecular materials. Coordination polymers. Properties and applications
8. Stability of coordination complexes. Applications
9. Reactivity of coordination compounds

Organic chemistry

1. Fundamental principles: reminders, definition, Hammond's postulate
2. Additions and eliminations
3. Substitutions
4. Sequential mechanisms

Secretariat Master Chemistry

https://master-chimie.edu.umontpellier.fr/