Level of study
BAC +4
ECTS
2 credits
Component
Faculty of Science
Description
The teaching of the module of strategies and tools in organic synthesis is centered on the deepening of the strategies of elaborations of molecules resulting or not from the natural environment using the tools of organic chemistry.
Hourly volumes* :
CM : 15 H
TD : 5 H
Objectives
Understand and be able to implement and plan the strategy for a given synthesis (key step, regio- and chemo-selectivity, use of protective groups, ...)
Necessary pre-requisites
Organic chemistry level L3
Knowledge control
Final written exam of 2 hours:
- Authorized documents: no
- Non-graphic calculator allowed: yes
- Internet allowed : no
Syllabus
Course : Inductive (problematic) and deductive pedagogy. Support(s) available on ENT (Moodle): Course documents, TD documents, exam annals and reference publications.
- Review of the fundamentals of retrosynthesis/protective groups/regio- and chemo-selectivity: (3h)
- Ionic and radical approaches to bond formation (3h)
- Cyclisation reactions (Baldwin's rules, Thorpe-Ingold effect, ...) (3h)
- Multi-component reaction (3h)
- Applications to the synthesis of biomolecules (3h)
TD (5h): Individual work, exercises to prepare before and during the session. Study of examples
Additional information
Teaching team :
Christophe Mathé
christophe.mathe@umontpellier.fr
Jean-Pierre Uttaro
Jean-pierre.uttaro@umontpellier.fr
Administrative contact(s):
Secretariat Master Chemistry
master-chimie @ umontpellier.fr @
https://master-chimie.edu.umontpellier.fr