Strategy and tools for organic synthesis

  • Study level

    BAC +4

  • ECTS

    2 credits

  • Training structure

    Faculty of Science

Description

The teaching of the Organic Synthesis Strategies and Tools module focuses on the development of strategies for the elaboration of molecules, whether or not derived from the natural environment, using the tools of organic chemistry.

Hourly volumes* :

CM: 15 H

TD: 5 H

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Objectives

Understand and be able to implement and plan the strategy for a given synthesis (key stage, regio- and chemo-selectivity, use of protective groups, etc.).

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Teaching hours

  • Strategy and tools for organic synthesis - CMLecture15h
  • Strategy and tools for organic synthesis - TDTutorial5h

Mandatory prerequisites

Organic chemistry, L3 level

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Knowledge control

Final written exam, 2 hours:

  • Authorized documents: no
  • Non-graphic calculator allowed: yes
  • Internet allowed: no
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Syllabus

Course: Inductive (problem-based) and deductive pedagogy. Support(s) available on ENT (Moodle): Course documents, TD documents, exam annals and reference publications.

 

  1. Fundamentals of retrosynthesis/protective groups/regio- and chemoselectivity: (3h)
  2. Ionic and radical approaches to bond formation (3h)
  3. Cyclization reactions (Baldwin's rules, Thorpe-Ingold effect, ...) (3h)
  4. Multi-component reaction (3h)
  5. Applications to biomolecule synthesis (3h)

 

 

TD (5h): Individual work, exercises to be prepared before and during the session. Study of examples

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Further information

Teaching team :

 

Christophe Mathé

christophe.mathe@umontpellier.fr

Jean-Pierre Uttaro

Jean-pierre.uttaro@umontpellier.fr

 

 

Administrative contact(s) :

Secretariat Master Chemistry

master-chimie @ umontpellier.fr

https://master-chimie.edu.umontpellier.fr

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