Strategy and tools in organic synthesis

The teaching of the module on strategies and tools in organic synthesis focuses on deepening students' understanding of strategies for developing molecules, whether derived from the natural environment or not, using the tools of organic chemistry.

Hourly volumes:

CM: 3 p.m.

Tutorial: 5 hours

Understand and be able to implement and plan the strategy for a given synthesis (key step, regio- and chemoselectivity, use of protective groups, etc.)

Organic Chemistry Level L3

2-hour final written exam:

• Authorized documents: no
• Non-graphing calculator permitted: yes
• Internet access: no

Course: Inductive (problem-based) and deductive teaching methods. Materials available on the digital workspace (Moodle): Course documents, tutorial documents, past exam papers, and reference publications.

1. Review of the fundamentals of retro-synthesis/protective groups/regio- and chemo-selectivity: (3 hours)
2. Ionic and radical approaches in bond formation (3 hours)
3. Cyclization reactions (Baldwin's rules, Thorpe-Ingold effect, etc.) (3 hours)
4. Multi-component reaction (3 hours)
5. Applications in biomolecule synthesis (3 hours)

TD (5 hours): Individual work, exercises to be prepared before and during the session. Case studies.

Teaching staff :

Christophe Mathé

christophe.mathe@umontpellier.fr

Jean-Pierre Uttaro

Jean-pierre.uttaro@umontpellier.fr

Administrative contact(s):

Master's Program in Chemistry Secretariat

Master's degree in Chemistry @ umontpellier.fr

https://master-chimie.edu.umontpellier.fr