Study level
BAC +4
ECTS
2 credits
Component
Faculty of Science
Description
The teaching of the Organic Synthesis Strategies and Tools module focuses on the development of strategies for the elaboration of molecules, whether or not derived from the natural environment, using the tools of organic chemistry.
Hourly volumes* :
CM: 15 H
TD: 5 H
Objectives
Understand and be able to implement and plan the strategy for a given synthesis (key stage, regio- and chemo-selectivity, use of protective groups, etc.).
Necessary prerequisites
Organic chemistry, L3 level
Knowledge control
Final written exam, 2 hours:
- Authorized documents: no
- Non-graphic calculator allowed: yes
- Internet allowed: no
Syllabus
Course: Inductive (problem-based) and deductive pedagogy. Support(s) available on ENT (Moodle): Course documents, TD documents, exam annals and reference publications.
- Fundamentals of retrosynthesis/protective groups/regio- and chemoselectivity: (3h)
- Ionic and radical approaches to bond formation (3h)
- Cyclization reactions (Baldwin's rules, Thorpe-Ingold effect, ...) (3h)
- Multi-component reaction (3h)
- Applications to biomolecule synthesis (3h)
TD (5h): Individual work, exercises to be prepared before and during the session. Study of examples
Further information
Teaching team :
Christophe Mathé
christophe.mathe@umontpellier.fr
Jean-Pierre Uttaro
Jean-pierre.uttaro@umontpellier.fr
Administrative contact(s) :
Secretariat Master Chemistry
master-chimie @ umontpellier.fr @
https://master-chimie.edu.umontpellier.fr