Medicinal chemistry

The aim of the medicinal chemistry course is to introduce students to the key stages in the process of developing molecules with biological activity. In particular, a description of the interactions involved, the notion of pharmocophores, bio-isosteria, etc., as well as structure-activity relationship studies will be covered, enabling students to envisage appropriate strategies and structural modifications.

Hourly volumes* :

WC: 3 p.m.

TD: 5 h

The aim of this course is to understand the issues involved in medicinal chemistry research.

Organic chemistry L3

Biomolecule Chemistry, M1 level:

Knowledge of the various families (structures, properties)

Final written exam, 2 hours:

• Authorized documents: no
• Internet allowed: no

Course : Inductive (problem-based) and deductive pedagogy. Support(s) available on ENT (Moodle): Course documents, TD documents, exam annals and reference publications.

1. Molecular interactions of biomolecules with their targets (1.5 h)
2. Pharmacophore and pharmacophore analogues (3 h)
3. Notions of bio-isostery/homologation/inversion of functions (4.5 h)
4. Structure-activity relationships (4.5 h)
5. Physico-chemical properties (1.5 h)

TD (5h): Individual work, exercises to prepare before and during the session.

Teaching team :

Christophe Mathé

christophe.mathe@umontpellier.fr

Administrative contact(s) :

Secretariat Master Chemistry

https://master-chimie.edu.umontpellier.fr/