Level of study
BAC +4
ECTS
2 credits
Component
Faculty of Science
Description
The first part of the course presents the fundamental knowledge of organometallic chemistry of transition metals. It starts with the description of the Metal-C bond allowing the understanding of its stability and chemical reactivity. In a second step, the power of this synthesis tool for the formation of C-H, C-C bonds, ... Examples of their applications in different fields will allow the acquisition of these reactions and their fields of applications: fine chemistry, catalytic transformations of industrial importance, synthesis of natural products, preparation of materials.
The second part of this course is dedicated to the chemistry of hetero-elements focused on the elements Silicon, Tin and Boron. This part aims at presenting the different methods of preparation of boron, tin and silicon reagents as well as the main transformations performed with these compounds, with applications in organic synthesis and materials synthesis.
CM : 13 H
TD : 7 H
Objectives
Organometallic and heteroelement chemistry offers unique synthesis tools whose numerous fields of use show their importance: synthesis of active principles, total syntheses, catalysis, molecular and macromolecular materials. The course aims at giving the first knowledge allowing an understanding and an acquisition of the basic concepts of this chemistry.
Necessary pre-requisites
Knowledge of molecular chemistry at the Licence L3 level: good knowledge of organic chemistry, the structure of matter, the nature of bonds and their reactivity.
Knowledge control
Final written exam of 2 hours:
- Authorized documents: no
- Non-graphic calculator allowed: yes
- Internet allowed : no
Syllabus
Course: 13H
Organometallic chemistry:
Structure/reactivity relationships of catalysts for metal-catalyzed reactions;
Influence of the nature of the ligands on the catalytic reaction processes;
Metallo-catalyzed reactions as tools in synthesis and synthesis strategy;
Sustainable development chemistry
Plan :
I - Introduction
II - Metal-ligand bonds
III - Counting the valence electrons (16/18 electron rule)
IV - Elementary reactions
V - Attack on ligands
VI - Catalysis
Hydrogenation of alkenes
Polymerization of alkenes
Metathesis of olefins
Coupling reaction
Hetero-element chemistry:
- Tin compounds
General
Reactivity in organic synthesis
- Silicon compounds
General
Reactivity in organic synthesis
- Boron compounds
General
Reactivity in organic synthesis
TD: 7H
Individual work, exercises to prepare before and during the session.
On both parts, application exercises (and their correction) will be drawn from recent literature and past exam subjects.
Additional information
Knowledge of coordination chemistry at the L3 level: knowledge of the structure of complexes, complexation reactions, nature and properties of ligands.