Organometallic Chemistry and Heterelement Chemistry

The first part of the course presents the fundamentals of transition-metal organometallic chemistry. It begins with a description of the metal-carbon bond to facilitate an understanding of its stability and chemical reactivity.  Next, we will demonstrate the power of this synthetic tool for forming C–H, C–C, and other bonds. Examples of their applications in various fields will help students grasp these reactions and their areas of application: fine chemistry, industrially important catalytic transformations, the synthesis of natural products, and the preparation of materials.

The second part of this course is devoted to the chemistry of heteroelements, with a focus on silicon, tin, and boron. This part aims to present the various methods for preparing boron-, tin-, and silicon-based reagents, as well as the main transformations carried out with these compounds, including their applications in organic synthesis and materials synthesis.

CM: 1:00 p.m. 

TD: 7 H

Organometallic and heteroelement chemistry offers unique synthetic tools, the importance of which is evident from their wide range of applications: synthesis of active ingredients, total syntheses, catalysis, and molecular and macromolecular materials. This course aims to provide students with the foundational knowledge necessary to understand and master the basic concepts of this field of chemistry.

Knowledge of molecular chemistry at the Bachelor's (L3) level: a solid understanding of organic chemistry, the structure of matter, the nature of chemical bonds, and their reactivity.

2-hour final written exam:

• Authorized documents: No
• Non-graphical calculators allowed: yes
• Internet access allowed: No

Class: 1:00 p.m.

Organometallic chemistry:

Structure-Reactivity Relationships of Catalysts for Metal-Catalyzed Reactions;

Influence of the nature of ligands on catalytic reaction processes; 

Metal-catalyzed reactions as tools in synthesis and synthetic strategies;

Sustainable Development Chemistry

Map:

I - Introduction

II - Metal-Ligand Bonds

III - Counting Valence Electrons (the 16/18-electron rule)

IV - Elementary Reactions

V - Attack on Ligands

VI – Catalysis

Hydrogenation of Alkenes

Polymerization of Alkenes

Olefin Metathesis

Coupling reaction

Chemistry of heteroelements:

1. Tin Compounds

General Information

Reactivity in Organic Synthesis

1. Silicon Compounds

General Information

Reactivity in Organic Synthesis

1. Boron Compounds

General Information

Reactivity in Organic Synthesis

TD: 7:00 a.m.

Individual work; exercises to be prepared before and during the session.

Both parts of the practice exercises (and their answers) will be drawn from recent literature and past exam questions.

Knowledge of coordination chemistry at the Bachelor's degree (L3) level: understanding of the structure of complexes, complexation reactions, and the nature and properties of ligands.