ECTS
120 credits
Duration
2 years
Training structure
Faculty of Pharmacy, Faculty of Science
Language(s) of instruction
French
Presentation
The IBIS pathway (Ingéniérie thérapeutique et Bioproduction en Biotechnologie santé - Red Biotechnologies) in the Health Biology specialization is designed to train students to create and produce the therapies of tomorrow, using biotechnology tools. Scientific advances in the understanding of human diseases are leading to healthcare innovations, most of which are being driven by biotech companies. The dynamism in France and worldwide in the creation of highly specialized companies with specific know-how must coincide with an evolution in the training courses leading to these new professions and skills.
These therapies are complex in nature and use.
ation, and obtaining them will therefore require multidisciplinary and cross-disciplinary skills in biotechnology, which the IBIS pathway aims to meet. The IBIS course is based on the needs of the sector's industrialists, as identified in the report by Leem (the professional organization of pharmaceutical companies) "Plan compétences, Biotech/innovations, santé2020".
The aspects developed concern :
- Biotechnological tools for the discovery of innovative therapeutic molecules, whether biological (recombinant proteins and antibodies, cells) or chemical.
- The engineering of bioprocesses for the industrial production of these compounds will also be developed, as will their formulation and vectorization (nanobiotechnologies).
In addition, an opening towards agro-environmental (green and yellow), marine (blue) and industrial (white) biotechnologies will be offered through cross-disciplinary teaching units with other Masters programs. In addition, an agreement is planned with Polytech Montpellier to offer a double engineering/master's degree:
- 2 students per year from Polytech Montpellier, GBA Biological and Food Engineering, to enter the health biotechnology sector (pharmaceuticals, cosmetics, etc.).
- 2 students per year from the Biology-Health/IBIS Master's program to enter the agrifood and nutrition sector.
To sum up, the IBIS course is an innovative training program in the field of health biotechnologies, designed to meet the needs of the sector's industrialists, by offering applied, multi-disciplinary, practical and integrated teaching, aimed at students in science, pharmacy, engineering or continuing education.
Objectives
At the end of the IBI training program, students will have mastered all the concepts required to create, produce, formulate and modify a biotechnology-based therapy, with a view to implementing personalized treatment for patients. The concepts acquired will apply not only to health biotechnologies, but also to other biotechnology fields (nutrition, cosmetology, agro-environment, etc.).
Know-how and skills
Scientific knowledge
- Comic strategies
- High-throughput screening, drug design
- Production and engineering of biomedicines
- Immunotherapy and monoclonal antibodies
- Bioinformatics and systems biology
- Bioproduction strategy
- Cell banks
- Process Engineering
- Physical chemistry, biochemistry, analytical chemistry
- Bioprocess development and monitoring (planning, scheduling, improving industrial performance)
- Biopharmaceuticals, nanobiotechnology
- Life cycle engineering (e.g. genetic and protein engineering)
Soft Skills
- Multi/interdisciplinary
- Transversality
- Project and team management
- Oral and written English
Knowledge of the environment
- Industrial property
- Risk management (biological and financial)
- Scientific and technological watch
- Ethics and regulations
Organization
Program
This course is co-sponsored by the Science and Pharmacy departments, offering students multidisciplinary training at the interface between pharmaceutical, biological and engineering sciences.
M1, a common base of knowledge in biotechnology and health :
M1 is designed to provide students with a common base of knowledge in biotechnology, whatever their previous training. With a view to multidisciplinarity and cross-disciplinarity, courses are dedicated to engineering sciences: functional genomics, statistics applied to biology, bioinformatics, immunotechnology and bioprocess engineering. A significant amount of teaching is also devoted to professionalization, with courses in scientific English and communication skills, and a long internship (minimum duration 4 to 5 months).
M2: a common foundation in innovation management, followed by a specialization in therapeutic engineering or biomanufacturing, open to apprenticeships:
M2 training is divided into Semester 1:
- a core curriculum (10 ECTS) covering intellectual property, innovation management and financing, bioethics and project and risk management, with 3 teaching units (UE);
- and a choice of 2 specialization blocks (20 ECTS), enabling students to progressively specialize in Therapeutic Engineering or Biomanufacturing.
. The Biotherapeutics Engineering specialization is divided into 5 units: New drug discovery, Biotherapy engineering, Formulation of biomedicines and biometarals, Nanotechnologies for health and Multidisciplinary lab project ;
. The bioproduction specialization is divided into 5 units: Bioprocess engineering (continuous and fed-batch; specificities of healthcare applications; recombinant protein production), Bioproduction and development of microbial biodiversity and Multidisciplinary lab projectc ;
Open to apprenticeships :
M2 is open to apprenticeships. Three course periods are identified. These are interspersed, for the traditional format, with project periods, a long-term internship and holidays; and for the sandwich format, with periods spent in companies and vacations. Whatever the M2 format chosen by the student, the second semester is entirely devoted to a long-term internship, preferably in industry, in order to encourage students to enter the job market at their place of internship/apprenticeship.
Innovative teaching methods:
IBIS training places a strong emphasis on innovative teaching methods , with a particular focus on project-based learning and putting students in real-life situations (experimental projects, etc.). This approach makes it possible to "enhance (students') motivation, venture beyond disciplines, and thus mobilize (students') cross-disciplinary skills, familiarize (students) with the, complexity of today's professional world, while helping to build a personal and professional project as they progress through their schooling."(Reverdy Catherine 2013 "L'apprentissage par projet : de la recherche", revue Technologie sciences et techniques industrielles https://eduscol.education.fr/sti/sites/eduscol.education.fr.sti/filles/ressources/techniques/5180/5180-186-p46.pdf.
In addition to mobilizing, consolidating and building students' knowledge, this pedagogical approach prepares them for their future careers, which require adaptability, creativity, teamwork, versatility, initiative and curiosity.
These innovative teaching methods are introduced as early as M1, then take their full place in M2, notably with the "multidisciplinary lab projects" which represent 5 to 9 ECTS, depending on the specialization chosen. This multidisciplinary project takes place over the whole semester, with several weeks blocked off in intensive mode. It is entirely in English and is based on "learning by doing". It will enable students to develop their professional skills: not only knowledge, but also know-how and interpersonal skills (teamwork, multi-disciplinary skills, project management, etc.). The first part of the program takes place in the Learning Lab (financed by the Muse Take-Off 1§2 AAPs), followed by the second part in practical work rooms on pilot-scale equipment. In this context, students will have to carry out an R§D project, such as setting up recombinant protein production. Students will be responsible for all stages of the project, from genetic construction and obtaining the production strain to pilot-scale production and protein purification.
Students work on a project management basis. This project-based working method is essential for the future managers who are the students in the IBIS program.
Select a program
Master 1 IBIS Therapeutic Engineering and Bioproduction in Biotechnology-Health
Master 1 IBIS Therapeutic Engineering and Bioproduction in Biotechnology-Health
Functional genomics
5 creditsExperimental models in biomedical research
5 creditsProtein engineering
5 creditsStatistics applied to biology
5 creditsBioinformatics and Antibody Bioinformatics
5 creditsImmunotechnology (UE PHARMACIE)
5 credits
English_FDS
5 creditsBioprocess engineering - Metabolism and bioproduction
3 creditsBioprocess engineering - Batch
2 creditsLong course
20 credits
Master 2 IBIS Therapeutic Engineering and Bioproduction in Biotechnology-Health
Master 2 IBIS Therapeutic Engineering and Bioproduction in Biotechnology-Health
Bioproduction and valorization of microbial biodiversity
3 creditsRecombinant protein production engineering
3 creditsMultidisciplinary Lab project 1 (UE PHARMACIE)
3 creditsBioethics and regulation (UE PHARMACIE)
3 creditsBioprocess engineering II, specific applications
2 creditsPromoting research and innovation
5 creditsContinuous and fed-batch bioprocess engineering
3 creditsProject and risk management
Multidisciplinary Lab project 2
6 credits
Stage long_FDS
30 credits
M2 IBIS Therapeutic Engineering and Bioproduction in Biotechnology-Health APPRENTICESHIP
Bioproduction and valorization of microbial biodiversity
3 creditsRecombinant protein production engineering
3 creditsMultidisciplinary Lab project 1 (UE PHARMACIE)
3 creditsBioethics and regulation (UE PHARMACIE)
3 creditsBioprocess engineering II, specific applications
2 creditsPromoting research and innovation
5 creditsContinuous and fed-batch bioprocess engineering
3 creditsProject and risk management
Multidisciplinary Lab project 2
6 credits
Stage long_FDS
30 credits
Admission
How to register
Applications for M1 must be made on the following platform:
- French & European students: follow the "My Master" procedure on the website: https: //www.monmaster.gouv.fr/
Target audience
The M1 course is open to science, technology and health students from :
- L3 Life Sciences
- L3 Science and Technology
- L3 CMI (Cursus Master Ingénieur) Biotechnologies
- DFASP1 research pharmacist.
Other students who do not necessarily have a background in biology (e.g. L3 Chemistry) can also join the course, depending on their academic record and possibly with a refresher course (MOOC...).
Direct entry into M2 will also be possible for a limited number of students from other M1 Biology-Health courses, health courses (pharmacists, doctors, interns) or engineering courses (partnership with Polytech Montpellier, Génie Biologique et Alimentaire).
Necessary prerequisites
L3 (or equivalent) with a grounding in (bio)chemistry, molecular biology, genetics, cell biology, microbiology and immunology.
Recommended prerequisites
Previous training in biotechnology is a plus.
And then
Further studies
If they so wish, students can pursue their doctoral studies in academia or industry.
Other students also have the option of specializing in project management by enrolling in management schools.
Professional integration
The main target sector is pharmaceuticals and biotechnology, whether in :
- Biotech companies
- Pharmaceutical and veterinary industries
- CRO (Contract Research Organisation) and CMO (Contract Manufacturing Organisation)
- Consulting firms
- Public research organizations (CNRS, Inserm, universities, etc.)
- CHU
- Partnership and technology transfer services (SATT, Inserm transfert, etc.)
- Competitive clusters
- Biotech incubators
with the following professions:
- Biotechnology project manager
- Pharmaceutical R&D engineer
- Responsible pharmacist in the pharmaceutical industry
- Biomanufacturing project manager
- Process Development Engineer
- Drug delivery systems engineer
- Design engineer in a public laboratory or on a platform
- SATT maturation engineer
- Biotech transfer business manager
- Industrial Property Officer