ECTS
120 credits
Duration
2 years
Training structure
Faculty of Pharmacy, Faculty of Science
Language(s) of instruction
French
Presentation
The IBIS program for Therapeutic Engineering and Bioproduction in Biotechnology and Health (Red Biotechnology) in the Biology and Health field is designed to train students to create and produce the therapies of tomorrow, using biotechnology tools. Scientific progress in the understanding of human diseases is leading to innovations in health, most of which are carried out by biotechnology companies. The French and global dynamism in the creation of highly specialized companies with specific know-how must coincide with an evolution of training leading to these new professions and skills.
These therapies are complex in their nature and their use
The IBIS program is designed to meet the needs of the pharmaceutical industry, which are listed in the report of the Leem (the professional organization for the pharmaceutical industry) entitled "Plan compétences, Biotech/innovations, santé2020" (skills plan, biotech/innovations, health2020). The IBIS course is based on the needs of the sector's industrialists, which are listed in the report of the Leem (the professional organization of drug companies) "Plan compétences, Biotech/innovations, santé2020".
The aspects developed concern:
- Biotechnological tools for the discovery of innovative therapeutic molecules, either biological (recombinant proteins and antibodies, cells) or chemical.
- The engineering of bioprocesses for the industrial production of these compounds will also be developed as well as their formulation and vectorization (nanobiotechnologies).
In addition, an opening towards agro-environmental (green and yellow), marine (blue) and industrial (white) biotechnologies will be offered through transversal teaching units with other Masters. Moreover, an agreement is planned with Polytech Montpellier in order to offer a double training validated by a double degree Engineer/Master:
- 2 students from Polytech Montpellier per year, Biological and Food Engineering GBA, to access the health biotechnology sector (pharmacy, cosmetics, etc.)
- to 2 students from the Biology-Health/IBIS Master's degree per year, to enter the field of agri-food and nutrition.
In summary, the IBIS program is an innovative training program in the field of health biotechnology, designed to meet the needs of the industry by offering applied, multidisciplinary, practical and integrated teaching for students in science, pharmacy, engineering or continuing education.
Objectives
At the end of the IBI training, students will have mastered all the concepts that will enable them to create, produce, formulate and modify a therapy derived from biotechnologies in order to set up a personalized treatment for patients. The concepts acquired will be applied to health biotechnologies but also to other fields of biotechnologies (nutrition, cosmetology, agro-environment...).
Know-how and skills
Scientific knowledge
- Strategies -omics
- High throughput screening, drug design
- Obtaining and engineering of biomedicines
- Immunotherapy and monoclonal antibodies
- Bioinformatics and systems biology
- Bioproduction strategy
- Cellular banks
- Process Engineering
- Physical chemistry, biochemistry, analytical chemistry
- Development and monitoring of bioprocesses (planning, scheduling, improvement of industrial performance)
- Biopharmaceuticals, nanobiotechnology
- Engineering of living organisms (e.g. genetic and protein engineering)
Soft Skills
- Multi/interdisciplinarity
- Transversality
- Project and team management
- Oral and written English
Knowledge of the environment
- Industrial property
- Risk management (biological and financial)
- Scientific and technological watch
- Ethics and regulations
Organization
Program
This course is co-sponsored by the Science and Pharmacy departments, thus offering students a multidisciplinary training at the interface between pharmaceutical, biological and engineering sciences.
The M1, a common base of knowledge in biotechnology and health:
M1 is designed to provide a common base of knowledge in biotechnology to students regardless of their previous training. In a logic of multidisciplinarity and transversality, the courses are both dedicated to engineering sciences: functional genomics, statistics applied to biology, bioinformatics, immunotechnology, bioprocess engineering. A significant amount of teaching is also dedicated to professionalization with scientific English and communication courses and a long internship (minimum duration of 4 to 5 months).
M2, a common base in innovation management, then a specialization in therapeutic engineering or in bioproduction, open to apprenticeship:
The training in M2 is declined in semester 1:
- A common core curriculum (10 ECTS) covering intellectual property, management and financing of innovation, bioethics, and project and risk management, with 3 teaching units (UE);
- and in 2 blocks of specialization (20 ECTS) to be chosen by the students, allowing them to progressively specialize in Therapeutic Engineering or in Bioproduction.
. The specialization in Biotherapeutics Engineering is divided into 5 UEs: New Drug Discovery, Biotherapeutics Engineering, Formulation of Biomedicines and Biometarals, Nanotechnologies for Health and Multidisciplinary lab project;
. The specialization in bioproduction is divided into 5 units: Bioprocess engineering (continuous and fed-batch; specificities of health applications; production of recombinant proteins), Bioproduction and valorization of microbial biodiversity and Multidisciplinary lab projectc ;
Openness to learning:
The M2 is open to apprenticeship. Three course periods are identified. They are interspersed, for the traditional format, with project periods, a long-term internship and holidays; and for the sandwich format, with periods of time spent in companies and vacations. Regardless of the M2 format chosen by the student, the second semester is entirely devoted to a long-term internship, preferably in industry, in order to promote the professional integration of students at their internship/apprenticeship site.
Courses integrating an innovative pedagogy:
The IBIS program places great emphasis on innovative teaching methods , particularly project-based learning and the placing of students in real-life situations (experimental projects, etc.). This approach makes it possible to "improve the motivation of (students), to venture beyond disciplines, and thus to mobilize the transversal skills of (students), to familiarize (students) with the, complexity of the current professional world, while helping to build a personal and professional project as they go along"(Reverdy Catherine 2013 "L'apprentissage par projet : de la recherche", revue Technologie sciences et techniques industrielles https://eduscol.education.fr/sti/sites/eduscol.education.fr.sti/filles/ressources/techniques/5180/5180-186-p46.pdf.
Thus, in addition to mobilizing, consolidating and building the students' knowledge, this pedagogy will prepare them for their future jobs which require adaptability, creativity, teamwork, versatility, initiative and curiosity.
These innovative teaching methods are introduced in M1 and then take their full place in M2, particularly with the "multidisciplinary lab projects" which represent 5 to 9 ECTS depending on the specialization chosen. This multidisciplinary project takes place over the entire semester, for which several weeks are blocked in intensive mode. It is entirely in English and based on "learning by doing". It will allow students to develop their professional skills: knowledge but also know-how and interpersonal skills (teamwork, multidisciplinary, project management, etc.). The first part takes place in the Learning Lab (financed by the AAP Muse Take-Off 1§2) and the second part is carried out in practical workrooms on pilot-scale equipment. Within this framework, the students will have to carry out an R§D project, for example the implementation of a recombinant protein production. The students will be responsible for all the steps: from genetic construction, obtaining the producing strain to pilot scale production and purification of the protein.
The students work in a project management mode. This method of working on projects is essential for the future managers that are the students of the IBIS program.
Select a program
Master 1 IBIS Therapeutic Engineering and Bioproduction in Biotechnology-Health
Master 1 IBIS Therapeutic Engineering and Bioproduction in Biotechnology-Health
Functional genomics
5 creditsExperimental models in biomedical research
5 creditsProtein engineering
5 creditsStatistics applied to biology
5 creditsBioinformatics and Antibody Bioinformatics
5 creditsImmunotechnology (UE PHARMACIE)
5 credits
English_FDS
5 creditsBioprocess Engineering - Metabolism and Bioproduction
3 creditsBioprocess Engineering - Batch
2 creditsLong course
20 credits
Master 2 IBIS Therapeutic Engineering and Bioproduction in Biotechnology-Health
Master 2 IBIS Therapeutic Engineering and Bioproduction in Biotechnology-Health
Bioproduction and valorization of microbial biodiversity
3 creditsEngineering of recombinant protein production
3 creditsMultidisciplinary Lab project 1 (UE PHARMACIE)
3 creditsBioethics and regulation (UE PHARMACIE)
3 creditsBioprocess Engineering II, application specificities
2 creditsValorization of research and innovation
5 creditsContinuous and fed-batch bioprocess engineering
3 creditsProject management and risk management
Multidisciplinary Lab project 2
6 credits
Long course_FDS
30 credits
M2 IBIS Therapeutic Engineering and Bioproduction in Biotechnology-Health APPRENTICESHIP
Bioproduction and valorization of microbial biodiversity
3 creditsEngineering of recombinant protein production
3 creditsMultidisciplinary Lab project 1 (UE PHARMACIE)
3 creditsBioethics and regulation (UE PHARMACIE)
3 creditsBioprocess Engineering II, application specificities
2 creditsValorization of research and innovation
5 creditsContinuous and fed-batch bioprocess engineering
3 creditsProject management and risk management
Multidisciplinary Lab project 2
6 credits
Long course_FDS
30 credits
Admission
How to register
Applications for M1 are made on the following platform:
- French & European students: follow the "My Master" procedure from the website: https: //www.monmaster.gouv.fr/
Target audience
The training is open at the M1 level to students in science, technology and health from :
- L3 Life Sciences
- L3 Sciences and technologies
- L3 CMI (Cursus Master Ingénieur) Biotechnologies
- Pharmacist DFASP1 in research program.
Other students who do not necessarily have a background in biology (e.g.: L3 Chemistry) can also join the course, depending on their file and possibly with a refresher course (MOOC...).
Integration directly into M2 will also be possible for a limited number of students from other M1 Biology-Health courses, health courses (pharmacists, doctors, interns) or engineering courses (partnership with Polytech Montpellier, Biological and Food Engineering).
Necessary pre-requisites
L3 (or equivalent) with a background in (bio)chemistry, molecular biology, genetics, cell biology, microbiology and immunology.
Recommended prerequisites
Previous training in biotechnology is an additional requirement.
And then
Further studies
Students, if they wish, can pursue their studies in a doctorate in an academic or industrial environment.
Other students can also specialize in the field of project management by entering management schools.
Professional integration
The main target sector is the pharmaceutical and biotechnology sector, either within :
- Biotechnology companies
- Pharmaceutical and veterinary industries
- CRO (Contract Research Organisation) and CMO (Contract Manufacturing Organisation)
- Consulting firms
- Public research organizations (CNRS, Inserm, Universities...)
- CHU
- Partnership and development services (Technology Transfer and Acceleration Companies (SATT), Inserm Transfer, etc.)
- Competitiveness clusters
- Incubators in the field of biotechnology
with the following trades:
- Biotechnology Project Manager
- Pharmaceutical R&D Engineer
- Pharmacist in charge of the pharmaceutical industry
- Bioproduction Project Manager
- Process Development Engineer
- Drug Delivery Systems Engineer
- Study engineer in public laboratory or on platform
- SATT maturation engineer
- Biotechnology transfer business manager
- Industrial Property Officer