ECTS
5 credits
Component
Faculty of Science
Description
Bioinformatics is concerned with the creation and use of numerical and mathematical approaches applied to the life sciences. The main applications concern the automatic processing of biological data and questions of data modeling, analysis and integration in the field of life biology.This course aims to provide a solid grounding in sequence analysis using bioinformatics tools, as well as in immunoinformatics. Theoretical aspects will be covered, and these will be reinforced by practical aspects (exercises and project work). This course may or may not be taught in English, depending on the student's level. The course comprises lectures and practical work, carried out by research professors.
Objectives
The aim is to meet the high-level R&D needs of companies and research organizations in the field of bioinformatics and immunoinformatics.
Skills developed in the areas of :
- Molecular biology databases
- Sequence analysis tools (alignments, motif detection, phylogenetic tree reconstruction, etc.). )
- Ensemble genome browser, 1000 genome project
- Introduction to immunogenetics, immunoinformatics and IMGT® (international ImMunoGeneTics information system)
- Immunoglobulin and T-cell receptor biocuration and comparative genomics
- Immunorepertoire analysis
- IMGT/mAb-DB, therapeutic monoclonal antibody database and related projects
At the end of this course, students will be able to analyze sequences using databases and bioinformatics tools. They will be able to read publications in the field and reproduce the work carried out in them. With regard to immunogenetics, they will be able to use IMGT databases and tools. They will have understood some of the scientific challenges in the field and how these can be tackled with the help of immunoinformatics.
Necessary prerequisites
basic knowledge of molecular biology and genetics, comfortable using computers.
Recommended prerequisites: proficiency in a programming language is a plus.
Knowledge control
Assessment of knowledge is based on continuous assessment (CCI), in the form of projects involving both oral presentations and reports.