Licence 1 CPES Modeling and Numerics in Life Sciences

Atomistics: Periodic table, Lewis models and VSEPR
# Electronic Configuration
# Periodic table
# Description of molecular chemical entities: Lewis and VSEPR

Introduction to Organic Chemistry and Basic Reaction Mechanisms
# BOM
# Stereochemistry
# Basics of Reactivity in Organic Chemistry
# Aliphatic nucleophilic substitutions
# β-eliminations
# Electrophilic addition on alkenes
# Nucleophilic addition on the example of organomagnesium

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Program of the first year of mathematics at the Lycée Joffre

# Reasoning and set vocabulary

# Complements of algebraic calculus, elementary analysis and geometry

# Enumeration

# Real analysis: numerical sequences, limits and continuity, differentiability, calculus of primitives and integrals.

# Complex numbers

# Differential equations

# Linear algebra: vectors, linear maps and matrices, bases and dimension,

# Asymptotic analysis

# Basics of statistics

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This modern language teaching is based on the written and oral practice of English, with particular emphasis on the scientific or socio-economic context.

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This is a first approach to the integrative biology of organisms.

This course, entitled "From Cells to Organisms", covers structure-function relationships at different scales, from the cell (or molecule) to the organism in its environment.

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The first-year program is as follows:

# Introduction to the problems of the contemporary world

# Introduction to economics Introduction to geopolitics

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The program below covers the two first-year computer science courses at the Lycée Joffre:

Algorithmics and Programming 1: Basic Concepts in Algorithmics and Programming:
• Notion of problem, problem instance, complexity, termination, proof of validity
• Algorithms and iterative processing
• Proof: validity, termination, complexity
• Linear structures: arrays, linked lists, stacks, queues
• Sorting: inserting, selecting, merging sorting, other sorting examples
• Introduction to recursive processing (dichotomous search, etc.)
• Python programming

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Use of computer systems: introduction to the main concepts of computer systems:
- Practical mastery of a Linux environment
- Knowledge of the main Linux commands
- Understanding of documentation pages (man)
- Sessions, files, directories, access rights
- Programs, processes, commands and command languages
- Console (terminal) vs. graphical execution mode
- Familiarization with shells, writing a few scripts

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Introduction to digital analysis 

# Basics, issues and limitations, representation of numbers in a machine

# Analytical add-ons for numerical analysis

# Numerical solution of nonlinear equations

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- Cell biology: cytoskeleton, membranes and membrane transport, extracellular matrix, organelles, origin of life and organization of viruses, prokaryotic and eukaryotic cells.

- Biochemistry: structure of biological macromolecules (nucleic acids, proteins, lipids and sugars), polymer chain definitions, classification and roles of biological polymers (proteins, nucleic acids, polysaccharides), folding and structuring of biological macromolecules, intra- and inter-molecular physicochemical interactions, biosynthesis and stability of macromolecules.

- Integrative and organismal biology: Angiosperm nutrition, animal and plant physiology

- Ecology: introduction to ecology, biogeochemical cycles, paleoecology

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General culture (epistemology and philosophy):

# history of ideas

# Epistemology of science and digital technology

#argumentatition and communication

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Synthetic program:

– Probabilistic vocabulary

– Random variables and probability distributions

– Expectation and variance

–Applications

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The first-year program is as follows:

# Introduction to the problems of the contemporary world

# Introduction to Economics

# Introduction to geopolitics

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Program of the first year of mathematics at the Lycée Joffre

# Reasoning and set vocabulary

# Complements of algebraic calculus, elementary analysis and geometry

# Enumeration

# Real analysis: numerical sequences, limits and continuity, differentiability, calculus of primitives and integrals.

# Complex numbers

# Differential equations

# Linear algebra: vectors, linear maps and matrices, bases and dimension,

# Asymptotic analysis

# Basics of statistics

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The introductory research project (one week to 10 days) at the end of the year is one of the original hallmarks of the CPES: it consists of immersion in a research laboratory, accompanied by presentations of research projects, with students participating for one or two half-days. The aim is to help students understand the challenges of a research project, and the contributions of modeling, computing and digital simulation. A poster or short report and an oral presentation before a panel of judges.

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The program below covers the two first-year computer science courses at the Lycée Joffre:

Algorithmics and Programming 1: Basic Concepts in Algorithmics and Programming:
• Notion of problem, problem instance, complexity, termination, proof of validity
• Algorithms and iterative processing
• Proof: validity, termination, complexity
• Linear structures: arrays, linked lists, stacks, queues
• Sorting: inserting, selecting, merging sorting, other sorting examples
• Introduction to recursive processing (dichotomous search, etc.)
• Python programming

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- Mendelian genetics

- Biology of animal and plant gametogenesis, animal and plant embryonic and post-embryonic development

- Post-embryonic development in animals (osteogenesis) and plants (primary and secondary growth)

- Genomics: eukaryotic, bacterial and viral genomes, expression of genetic information and protein addressing, replication.

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VBA Programming in Excel Development of VBA Macros in Excel:

# Practice macros in Excel

# Application of the basics of the VBA language in Excel

# Debugging VBA macros in Excel

# Writing custom functions

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General culture (epistemology and philosophy):

# history of ideas

# Epistemology of science and digital technology

#argumentatition and communication

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This modern language teaching is focused on the written and oral practice of English, with a particular emphasis on a scientific or socio-economic context.

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In this course, we cover each stage of the life cycle of organisms (mainly metazoans and angiosperms) through a series of practical exercises covering: embryonic development (including organ development, cell differentiation and growth processes), acquisition of reproductive capacity (including stages associated with meiosis and gametogenesis), and fertilization. This series of practical exercises is combined with a series of tutorials on the transmission of genetic information. 

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