Training structure
Faculty of Science
Program
Structural Biology
5 creditsBootcamp
5 creditsCHOICE 1
5 creditsYour choice: 1 of 2
Statistics applied to biology
5 creditsFunctional genomics
5 credits
Introduction to quantitative Biology
Synthetic Biology - Praticals
5 creditsImaging Biologicals Systems - Praticals
5 credits
Stage_FDS
15 creditsTER_FDS
5 creditsPractical Modelling and Simulation of Biological Systems
5 creditsApplied Structural Biology
5 credits
Bootcamp
ECTS
5 credits
Component
Faculty of Science
The Bootcamp is an intensive course at the beginning of the first semester, before the start of the courses that characterize the courses. Its aim is to refresh and/or bring students up to speed on the basics of mathematics, physics, computer science and biology.
The course will be adapted to suit the students recruited, with the aim of ensuring a more homogeneous start to the course. Students will be immersed in a variety of role-playing games, divided into small groups. They will have to solve enigmas using their knowledge of biology, physics/mathematics, chemistry and programming, as in an escape game over several days.
Statistics applied to biology
ECTS
5 credits
Component
Faculty of Medicine
Functional genomics
ECTS
5 credits
Component
Faculty of Science
The aim of this course is to introduce functional genomics technologies in -omics, and to present examples of biological questions that can be answered using these technologies.
This unit aims to present "omics" functional genomics technologies, and some biological questions that they can address.The lectures are given by both associate professors and researchers.
Introduction to functional genomics: approaches, concepts and methods
An introduction to functional Genomics: approaches, concepts and methods
V. Coulon, UM / IGMM
Organisation des génomes / Genome organization
Techniques de séquençage / DNA sequencing methodsL. Journot, IGF
Organisation 3D des génomes / 3D genome organisation J. Poli, UM / IGH
Genome topological organization and replication / Organisation topologique et réplication des génomes-V. Coulon, UM / IGMM
Régulation spatio-temporelle de l'expression des génomes / Spatio-temporal regulation of gene expressionTranscriptionEpissage / Splicing-V. Coulon, UM / IGMM
ARN non-codants / non-coding RNAsV. Coulon, UM / IGMM
Interactomique / InteractomicsIan Robbins, UM / IGMM
Proteomics and Pharmacogenomics / Protéomique et pharmacogénomiqueC. Bécamel, UM / IGF
Animal Models / Modèles animaux
Using Mice in Functional Genomics / Utilisation de la souris en génomique fonctionnelle F. Poulat, IGH
La Drosophile en génomique fonctionnelle / Using Drosophila in Functional Genomics -F. Juge and S. Chambeyron, IGH
Analyse et présentation d'articles scientifiques/ Scientificarticles analysis and presentation(15min + 10 min discussion per group of 3 students)
Introduction to quantitative Biology
Component
Faculty of Science
This EU aims to provide a broad overview of emerging quantitative interdisciplinary fields in the biosciences, ranging from cutting-edge experimental techniques in microscopy and synthetic biology, to systems approaches.
In an innovative way, these methodological aspects will be presented in the context of biological and biophysical concepts such as the robustness and optimality of biological systems, gene regulation and the fundamental principles underlying membrane and genome organization.
The main topics will first be introduced with traditional lectures and will be developed through individual or team projects where students will learn to apply specific techniques through examples, and see how these can be used to explore specific biological questions. These projects will involve bibliographical studies, the use of existing code or the development of new code (depending on the student's experience) and will make up half of the final assessment.
Synthetic Biology - Praticals
ECTS
5 credits
Component
Faculty of Science
In this (practical) teaching unit, we will first introduce the general concepts of synthetic biology, which will then be applied to (assessed) student team projects. We will provide basic knowledge to understand the full range of fundamental concepts, approaches and current tools of synthetic biology that will be exploited throughout the course and practical sessions, ranging from gene design and synthesis to genetic library construction, from fluorescence measurements (e.g. plate readers. ) to flow cytometers.
Imaging Biologicals Systems - Praticals
ECTS
5 credits
Component
Faculty of Science
Students will acquire the fundamental basis and advanced microscopy techniques needed to push back the boundaries of knowledge in biology. Teaching is progressive and modular, built entirely around practical projects: building a simple microscope, using state-of-the-art microscopes to study complex biological processes in bacteria and eukaryotes. Students will be immersed in a stimulating scientific environment. Training will be based on significant personal investment through experimental projects, article reviews and case studies. Communication skills will also be developed through oral presentations and written reports.
Stage_FDS
ECTS
15 credits
Component
Faculty of Science
Two to 4-month internship in a research laboratory or company in France or abroad.
TER_FDS
ECTS
5 credits
Component
Faculty of Science
The aim of the TER course is to prepare students to organize and carry out an in-depth bibliographical analysis, enabling them to approach their internship with a knowledge of the state of the art in the field, and in particular to produce a relevant and thoughtful introduction to their experimental work.
Practical Modelling and Simulation of Biological Systems
ECTS
5 credits
Component
Faculty of Science
Applied Structural Biology
ECTS
5 credits
Component
Faculty of Science
This practical course is based on mini-projects involving the application of techniques for studying the structure of biomolecules (X-ray crystallography, NMR, cryo-EM, mass spectrometry). Students will also learn about the biophysical and biochemical techniques used to characterize the molecules analyzed and their interactions.
For each approach, students will learn the basic principles, sample preparation requirements, data acquisition and analysis.
Admission
How to register
Applications can be submitted on the following platforms:
- French & European students: follow the "Mon Master" procedure on the website: https: //www.monmaster.gouv.fr/
- International students from outside the EU: follow the "Études en France" procedure: https: //pastel.diplomatie.gouv.fr/etudesenfrance/dyn/public/authentification/login.html