Molecular and metabolic bases of hereditary diseases

The program covers the important basic concepts of gene organization and different levels of gene regulation, as well as essential concepts of human population genetics that play an important role as risk factors. The molecular mechanisms involved in monogenic or multifactorial diseases are presented using specific examples. This also provides an opportunity to discover the new technological tools available (pan-genomic techniques, high-throughput genotyping, etc.) that are enabling major advances in this field. Finally, the module offers an overview of the impact of this research on medical practice through the development of cell therapy, gene therapy, and pharmacogenomics.

This module aims to provide solid training in human genetics, focusing on the molecular and mechanistic aspects of diseases and addressing risk factors and strategies developed to treat these diseases. It draws on faculty and researchers from both the Faculty of Medicine and the Faculty of Science, demonstrating the consistency between fundamental research and research applied to medicine.

The aim of this module is to provide a solid background in human genetics, focusing on the molecular aspects and mechanisms of diseases and addressing risk factors and new strategies for treating these diseases. Classes are taught by teachers and researchers from both the Faculty of Medicine and the Faculty of Science, as basic and medical research are equally important in understanding and developing treatments for inherited diseases.

These different approaches enable the development of:

-cross-functional skills and openness to different approaches

-critical thinking skills during the oral presentation of a scientific article

-his oral communication skills

genetics/cellular and molecular biology/genomics/cellular metabolism

First session: Written: 80% and oral (presentation of a scientific article): 20%

2nd session: Written