Molecular and Metabolic Bases of Hereditary Diseases

The program covers the key basic concepts of gene organization and the various levels of gene regulation, as well as essential concepts in human population genetics that play an important role as risk factors. The molecular mechanisms involved in monogenic and multifactorial diseases are presented using specific examples. This also provides an opportunity to explore the new technological tools available (pan-genomic techniques, high-throughput genotyping, etc.) that are driving major advances in this field. Finally, the module offers an overview of the impact of this research on medical practice through the development of cell therapy, gene therapy, and pharmacogenomics.

The purpose of this module is to provide a solid foundation in human genetics, focusing on the molecular and mechanistic aspects of diseases and addressing risk factors and strategies developed to treat these diseases. It draws on faculty members and researchers from both the School of Medicine and the School of Sciences, thereby demonstrating the connection between basic research and research applied to medicine.

The aim of this module is to provide a solid foundation in human genetics, focusing on the molecular aspects and mechanisms of diseases and addressing risk factors and new strategies for treating these diseases. Classes are taught by faculty members and researchers from both the Faculty of Medicine and the Faculty of Science, as basic and medical research are equally important in understanding and developing treatments for inherited diseases.

These different approaches make it possible to develop:

-cross-functional skills and an openness to different approaches

-his critical thinking skills during the oral presentation of a scientific article

-his oral communication skills

genetics/cellular and molecular biology/genomics/cellular metabolism

Session 1: Written exam: 80%; oral exam (presentation of a scientific article): 20%

Session 2: Written