Cellular Communication and Pharmacology

The mechanism of action of drugs is based on an interaction with a target cell structure of the organism leading to the modulation of its function. Thus, this course has two main components. The^first part will aim to make students aware of the different modes of cellular communication, the different chemical messengers, their targets and their modes of action. The second part will aim to give students the basic knowledge of pharmacology, i.e. understanding the mode of action of drugs and their fate in the body. For this, the concepts of pharmacodynamics (ligand-receptor interaction, effect-dose relationship) and pharmacokinetics (ADME: absorption-distribution-metabolism-excretion) will be addressed. In addition, drug targets, intracellular signaling and therapeutic indications will be discussed.

- to know the different modes of cellular communication, the different chemical messengers and their cellular targets, as well as the main intracellular signaling pathways

- know the concepts of pharmacodynamics and pharmacokinetics

- know how to deal with a problem and carry out the different stages of an experimental approach independently

- know how to analyze and synthesize data in order to exploit them

- interpret experimental data or analyze a research document