Study level
BAC +3
ECTS
4 credits
Component
Faculty of Science
Description
From the same genome, the different cells making up a multicellular organism will acquire diverse cell fates in order to acquire distinct cellular functions. In addition to the genome, epigenetic regulations governing the control of genome expression will be crucial in establishing phenotypes. The aim of this course is to convey the concepts and methodologies needed to study the transmission of hereditary information via so-called epigenetic mechanisms.
Objectives
-Knowledge :
Genome composition,
Principles of eukaryotic gene regulation,
Gene networks,
Chromatin effects, epigenetic modifications, epigenome,
Chromosome dynamics in nuclei, 3D genome architecture.
-Know-how :
Acquire all epigenetic methodologies,
Interpret gene expression profiles,
Interpret genome-wide, epigenome-wide and transcriptomic data.
-People skills :
Transdiciplinary ;
Autonomous in project design and genetic.
Necessary prerequisites
MOLECULAR AND CELLULAR BIOLOGY