Level of study
BAC +3
ECTS
4 credits
Component
Faculty of Science
Description
From the same genome, the different cells constituting a multicellular organism will acquire diverse cell fates in order to acquire distinct cellular functions. In addition to the genome, epigenetic regulations governing the control of genome expression will be crucial in establishing phenotypes. The objective of this course is to convey the concepts and methodologies for studying the transmission of hereditary information via so-called epigenetic mechanisms.
Objectives
-Knowledge:
Genome composition,
Principles of eukaryotic gene regulation,
Gene networks,
Chromatin effects, epigenetic modifications, epigenome,
Chromosome dynamics in nuclei, 3D genome architecture.
-Know-how :
To have acquired all the methodologies in epigenetics,
Know how to interpret gene expression profiles,
Interpret genome-wide, epigenome-wide and transcriptomic analysis data.
-Know how to be :
Transdiciplinary;
Autonomous in project design and genetic.
Necessary pre-requisites
MOLECULAR AND CELLULAR BIOLOGY