From the Molecule to the Cell in APP

The UE "From the molecule to the cell in APP" aims to give L1 students the basic notions of biology that will be necessary to follow the UE of biochemistry, genetics and molecular biology in the following semesters. The structure of biomolecules (nucleic acids, proteins, lipids and sugars) and the structural organization of the cell will be detailed with a view to understanding the origin of life and the organization of viruses, prokaryotic and eukaryotic cells.

The program of this EU will be declined on :

• 6 Tutoring sessions of 3 hours 
• 6 TP of 3h
• 3 Scientific Conferences

• Understand the concept of cell (smallest unit of living organism)
• Recognize and compare the different types of cells: prokaryote and eukaryote (animal and plant)
• Know how to recognize and classify different molecules according to their structure
• To know the nature of the constituent bonds of biomolecules
• Understand how different types of molecules can interact
• To know the basic structure of biological membranes
• Know the different types of membrane transporters
• To know the different junctions and adhesion molecules, their function and location
• Know the different types of extracellular matrices
• To know how to define the different types of organelles, their function and their location at the cellular level
• Recognize an organelle from its structure in the TEM or SEM
• Know the 3 types of cytoskeleton structure
• To know their cellular locations and their roles
• Mobilize the basic notions of biology and microscopy to deal with a simple problem in the field or to analyze a micrograph.
• Know how to use a photonic microscope
• Perform a simple cyto/histological preparation
• Perform a simple cyto/histological stain
• Perform a Gram stain
• To represent a microscopic observation in the form of a captioned drawing, respecting the size proportions of the various cellular elements
• Make height measurements using magnification or a scale bar
• Make a scale on a drawing or a micrograph
• Differentiate between eukaryotic and prokaryotic cells
• To recognize an animal cell and a plant cell
• Respect the rules of hygiene and safety of a laboratory

100% Continuous assessment

Recommended prerequisites*:

Knowledge of biology (science final year) is recommended.