Biochemistry in APP

The course “Biochemistry and Molecular Biology of the Cell 1” is a continuation of the first-semester course “From Molecules to Cells,” which laid the structural foundations of living organisms. In this course, students will learn the fundamentals of biochemistry, replication, transcription, translation, intracellular movements, and bioenergetics.

The curriculum for this course unit will be organized as follows:

• 2 tutoring sessions, 3 hours each 
• 2 3-hour lab sessions
• 1 Scientific Conferences

and will be included in the organic chemistry course in the APP (HAV226C), worth 4 ECTS:

• Understanding the Importance of Catalyzing a Reaction
• How to Write a Reaction Balance
• Predicting the direction of responses based on metabolite concentrations
• How to Calculate the Maximum Rate of an Enzymatic Reaction
• Knowing how to calculate an enzyme's affinity for a substrate
• Determine the optimal operating conditions for an enzyme (pH and temperature)
• Enzyme with inhibitors
• Structure and Function of Enzymes

• Understand the basic principles and concepts of Michaelis-Menten kinetics and cellular energetics in order to understand the regulation of metabolism.
• Basic knowledge of the structure and metabolism of carbohydrates, particularly glycolysis.
• Understand that the “spontaneity” of the reactions that make up a metabolic pathway in cells is linked to a combination of intracellular factors (variable concentrations of different metabolites over time) and extracellular factors (concentrations of secreted metabolites, hormonal signals, etc.).
• Be able to identify and write condensation and hydrolysis reactions
• Locate and quantify enzymatic activity; measure a reaction rate. Quantify a metabolite.

100% continuous assessment

Recommended prerequisites*: High school courses (science track) are strongly recommended