ECTS
120 credits
Duration
2 years
Training structure
Faculty of Pharmacy
Language(s) of instruction
French
Presentation
With close links to internationally recognized research institutes (IBMM, IRCM, IRMB, etc.), this program provides the skills and knowledge needed for a career at the Chemistry-Biology-Health interface. The program will provide cutting-edge expertise in chemistry applied to the development of innovative therapies.
Objectives
Design and implementation of cutting-edge start-up chemistry applied to the development of innovative therapies
Know-how and skills
- Design and develop chemical tools for exploring living organisms (probes, molecular agents and/or nano-objects for targeting and vectorization, bioconjugates).
- Design molecules, therapeutic and diagnostic systems, and immunoconjugates with a view to innovation and commercial development in healthcare.
- Developing new therapeutic approaches and biotherapies
- Adding value to research results
- Manage and lead interdisciplinary projects at the interface between chemistry and biology.
Organization
Knowledge control
Program
Select a program
M1 Drug Science and Health Products
M2 Innovation in Health Chemistry and Therapeutic Targeting
Drug design: case studies
2 creditsTargeted therapies
2 creditsModeling molecule-target therapeutic interactions 1
2 creditsImmunotargeting
2 creditsModeling molecule-target therapeutic interactions 2
2 creditsTherapeutic peptides § Peptidomimetics
Specific courses
Drug design: case studies
2 creditsTargeted therapies
2 creditsModeling molecule-target therapeutic interactions 1
2 creditsImmunotargeting
2 creditsModeling molecule-target therapeutic interactions 2
2 creditsTherapeutic peptides § Peptidomimetics
Chemobiology (67% ENSCM)
2 creditsStructure-based drug design
2 creditsNanotechnologies for health (UE PHARMACIE)
2 creditsTissue engineering and cell therapy
Core syllabus
Chemobiology (67% ENSCM)
2 creditsStructure-based drug design
2 creditsNanotechnologies for health (UE PHARMACIE)
2 creditsTissue engineering and cell therapy
Quality and technical/regulatory aspects: Technico réglem
ECTS
3.5 credits
Component
Faculty of Pharmacy
Toxicological investigation
ECTS
5 credits
Component
Faculty of Pharmacy
Cell Biology
ECTS
5 credits
Component
Faculty of Science
The program offers a refresher course and an in-depth study of the major concepts and methodologies of cell biology, organized around different themes:
1 Cytoskeleton:Introduction to the different types of cytoskeleton. Polymerization properties of actin and tubulin. Proteins associated with the cytoskeleton and regulating polymerization. Molecular motors. Principles of cell migration.
2.cell adhesion & signaling: cell-cell and cell-extracellular matrix adhesive structures, their molecular organization and dynamics. Functions and regulation during development and pathogenesis. Regulation by signaling pathways. Mechanotransduction.
3 Addressing and cell trafficking: Ubiquitination and proteasome. Addressing to subcellular compartments, endocytosis and secretion pathways. Molecular basis of vesicular transport, budding, fusion, molecular motors. Signaling in membrane trafficking, trafficking-related genetic diseases and pathogen detour.
4 Cell cycle: Historical introduction. Molecular regulation of the cell cycle. The mitotic spindle, microtubule dynamics and molecular motors, chromosome attachment mechanisms, checkpoints, regulation of mitosis exit and cytokinesis. Mitotic disorders associated with cancer cells.
5 Stem cells: cell differentiation, toti-, pluri- and multipotency, embryonic, adult and cancer stem cells.
6 Programmed cell death: Apoptosis, autophagy, necrosis. Stages and modalities of apoptosis, signaling pathways involved. Role in maintaining homeostasis. Pathophysiological consequences of deregulation of programmed cell death.
Different study models are presented, to introduce the importance of the contribution of biological diversity to the discovery of cellular and molecular mechanisms, and to the understanding of human pathologies.
The program offers a refresher of knowledge and an in-depth study of the major concepts and methodologies of cell biology, organized around different themes:
1. Cytoskeleton: Introduction to the different types of cytoskeleton. Polymerization properties of actin and tubulin. Proteins associated with the cytoskeleton and regulating polymerization. Molecular motors. Principles of cell migration.
2. Cellular Adhesion & Signaling: Cell-cell and extracellular cell-matrix adhesive structures, their molecular and dynamic organization. Functions and regulations during development and pathogenesis. Regulation by signaling channels. Mechanotransduction.
3. Addressing and cell traffic: Ubiquitination and proteasome. Addressing to subcellular compartments, endocytosis and secretion pathways. The molecular bases of vesicular transport, budding, fusion, molecular motors. Signaling in membrane trafficking, genetic diseases linked to trafficking and diversion by pathogens.
4. Cell cycle: Historical introduction. Molecular regulation of the cell cycle. The mitotic spindle, microtubule and molecular motor dynamics, chromosome attachment mechanisms, checkpoints, regulation of mitosis output and cytokinesis. Mitotic disorders associated with cancer cells.
5. Stem cells: cell differentiation, toti-, pluri-and multipotency, embryonic, adult and cancer stem cells.
6. Programmed cell death: Apoptosis, autophagy, necrosis. Stages and modalities of apoptosis, signaling pathways involved. Role in maintaining homeostasis. Physiopathological consequences of deregulation of programmed cell death.
Different study models are presented, in order to introduce the importance of the contribution of biological diversity in the discovery of cellular and molecular mechanisms, as well as in the understanding of human pathologies.
Molecular pharmacology and therapeutics
ECTS
5 credits
Component
Faculty of Pharmacy
Registration and Health Product Economics
ECTS
5 credits
Component
Faculty of Pharmacy
Analytical techniques for drug quality control
ECTS
5 credits
Component
Faculty of Pharmacy
Théra and Pharmaco Chemistry
ECTS
5 credits
Component
Faculty of Pharmacy
Molecular Pharmacochemistry section
ECTS
2 credits
Component
Faculty of Pharmacy
Therapeutic Chemistry - TC peptide synthesis
ECTS
3 credits
Component
Faculty of Pharmacy
R&D and Drug Registration
ECTS
5.5 credits
Component
Faculty of Pharmacy
Pharmacokinetics, pharmacodynamics and biopharmacy
ECTS
5 credits
Component
Faculty of Pharmacy
Advanced analysis techniques for Medi development.
ECTS
5 credits
Component
Faculty of Pharmacy
Fundamentals of health product engineering
ECTS
5 credits
Component
Faculty of Pharmacy
Basic element of health product engineering CT
Component
Faculty of Pharmacy
Basic element of health product engineering CC
Component
Faculty of Pharmacy
Introduction to aging and anti-aging
ECTS
5 credits
Component
Faculty of Pharmacy
Corporate knowledge and patent valuation
ECTS
5 credits
Component
Faculty of Science
Are you an L3/M1 student in Languedoc-Roussillon? Would you like to work on a dormant scientific patent in small groups with students from other disciplines, in project mode? Be supported and challenged by professional business creation coaches? Sign up for the PEPITE Patent Project to present a project for the creation of an innovative company based on the exploitation of a real patent supplied by a local research team that will open its doors to you!
Why?
-Because you can start your own business whatever your field of study.
To be selected by an incubator-type support structure
-Build a network in the field of entrepreneurship and innovation
PEPITE Patent Project, what is it? A teaching unit made up of a number of key moments:
a 3-day "tool training" seminar
-regular meetings with coaches
-deliverables: briefing note, market study, business plan
a 10-minute final pitch to present your innovative company
Drug design: Introduction to drug design
ECTS
5 credits
Component
Faculty of Pharmacy
Microscopies and spectroscopies for biology
Study level
BAC +4
Component
Faculty of Pharmacy
Industrial development of aging models
ECTS
5 credits
Component
Faculty of Pharmacy
Statistics and scientific watch
ECTS
3 credits
Component
Faculty of Pharmacy
Quality and technical/regulatory aspects: Technico réglem
ECTS
3.5 credits
Component
Faculty of Pharmacy
R&D and Drug Registration
ECTS
5.5 credits
Component
Faculty of Pharmacy
Statistics and scientific watch
ECTS
3 credits
Component
Faculty of Pharmacy
Framed Work R&D Medicines and Health Products
ECTS
5 credits
Component
Faculty of Pharmacy
TER Health product development pathway
ECTS
5 credits
Component
Faculty of Pharmacy
TER Aging and anti-aging start-up course
ECTS
5 credits
Component
Faculty of Pharmacy
TER Regulatory Environment track
ECTS
5 credits
Component
Faculty of Pharmacy
TER Structural Biology pathway
ECTS
5 credits
Component
Faculty of Pharmacy
TER Innovation in Health Chemistry pathway
ECTS
5 credits
Component
Faculty of Pharmacy
TER Health product analysis pathway
ECTS
5 credits
Component
Faculty of Pharmacy
Drug design: case studies
ECTS
2 credits
Component
Faculty of Pharmacy
Modeling molecule-target therapeutic interactions 1
ECTS
2 credits
Component
Faculty of Pharmacy
Modeling molecule-target therapeutic interactions 2
ECTS
2 credits
Component
Faculty of Pharmacy
Therapeutic peptides § Peptidomimetics
Component
Faculty of Pharmacy
Drug design: case studies
ECTS
2 credits
Component
Faculty of Pharmacy
Modeling molecule-target therapeutic interactions 1
ECTS
2 credits
Component
Faculty of Pharmacy
Modeling molecule-target therapeutic interactions 2
ECTS
2 credits
Component
Faculty of Pharmacy
Therapeutic peptides § Peptidomimetics
Component
Faculty of Pharmacy
Chemobiology (67% ENSCM)
Study level
BAC +5
ECTS
2 credits
Component
Faculty of Science
The course will focus on organic chemistry and post-functionalization of biomolecules applied to peptides, proteins and nucleic acids (DNA and RNA) with applications in gene therapy, biosensing and design of probes for biological studies.
Hourly volumes* :
CM: 15 H
TD: 5 H
Structure-based drug design
ECTS
2 credits
Component
Faculty of Pharmacy
Nanotechnologies for health (UE PHARMACIE)
ECTS
2 credits
Component
Faculty of Pharmacy
Tissue engineering and cell therapy
Component
Faculty of Pharmacy
News and recent advances in drug science
ECTS
4 credits
Component
Faculty of Pharmacy
Comnunication - Application of English
ECTS
3 credits
Component
Faculty of Pharmacy
Chemobiology (67% ENSCM)
Study level
BAC +5
ECTS
2 credits
Component
Faculty of Science
The course will focus on organic chemistry and post-functionalization of biomolecules applied to peptides, proteins and nucleic acids (DNA and RNA) with applications in gene therapy, biosensing and design of probes for biological studies.
Hourly volumes* :
CM: 15 H
TD: 5 H
Structure-based drug design
ECTS
2 credits
Component
Faculty of Pharmacy
Nanotechnologies for health (UE PHARMACIE)
ECTS
2 credits
Component
Faculty of Pharmacy
Tissue engineering and cell therapy
Component
Faculty of Pharmacy
Innovation in health chemistry internship
ECTS
20 credits
Component
Faculty of Pharmacy
Tutored project Innovation in health chemistry
ECTS
10 credits
Component
Faculty of Pharmacy