ECTS
120 credits
Duration
2 years
Training structure
Faculty of Pharmacy
Language(s) of instruction
French
Presentation
In close collaboration with internationally recognized research institutes (IBMM, IRCM, IRMB, etc.), this program allows students to acquire the skills and knowledge necessary for a professional project at the Chemistry-Biology-Health interface. This course will enable students to acquire cutting-edge expertise in chemistry applied to the development of innovative therapies.
Objectives
Design and implementation of advanced chemistry start-up strategies applied to the development of innovative therapies
Know-how and skills
- Design and develop chemical tools to explore living organisms (probes, molecular agents and/or nano-objects for targeting and vectorization, bioconjugates)
- Designing molecules, therapeutic and diagnostic systems, and immunoconjugates for innovation and commercial development in healthcare
- Develop new therapeutic approaches, biotherapies
- Valorize research results
- Manage and lead interdisciplinary projects at the interface between chemistry and biology.
Organization
Knowledge control
Program
Select a program
M1 Drug Sciences and Health Products
M2 Innovation in Health Chemistry and Therapeutic Targeting
Drug design: case studies
2 creditsTargeted therapies
2 creditsModeling molecule-target therapeutic interactions 1
2 creditsImmunotargeting
2 creditsModeling molecule-target therapeutic interactions 2
2 creditsTherapeutic peptides § Peptidomimetics
Specific courses
Drug design: case studies
2 creditsTargeted therapies
2 creditsModeling molecule-target therapeutic interactions 1
2 creditsImmunotargeting
2 creditsModeling molecule-target therapeutic interactions 2
2 creditsTherapeutic peptides § Peptidomimetics
Chemobiology (67% ENSCM)
2 creditsStructure-based drug design
2 creditsNanotechnologies for health (EU PHARMACY)
2 creditsTissue engineering and cell therapy
Core syllabus
Chemobiology (67% ENSCM)
2 creditsStructure-based drug design
2 creditsNanotechnologies for health (EU PHARMACY)
2 creditsTissue engineering and cell therapy
Quality and technical/regulatory aspects: Technico réglem
ECTS
3.5 credits
Component
Faculty of Pharmacy
Toxicological investigation
ECTS
5 credits
Component
Faculty of Pharmacy
Cellular biology
ECTS
5 credits
Component
Faculty of Science
The program offers a refresher course and an in-depth study of the major concepts and methodologies of cell biology, organized around different themes:
Cytoskeleton:Introduction to the different types of cytoskeleton. Polymerization properties of actin and tubulin. Proteins associated with the cytoskeleton and regulating polymerization. Molecular motors. Principles of cell migration.
Cellular Adhesion & Signaling: Adhesive structures cell-cell and cell-extracellular matrix, their molecular organization and dynamics. Functions and regulations during development and pathogenesis. Regulation by signaling pathways. Mechanotransduction.
3. addressing and cell trafficking: Ubiquitination and proteasome. Addressing to subcellular compartments, endocytosis and secretion pathways. Molecular basis of vesicular transport, budding, fusion, molecular motors. Signaling in membrane trafficking, genetic diseases related to trafficking and detour by pathogens.
4.cell cycle:Historical introduction. Molecular regulation of the cell cycle. Mitotic spindle, microtubule dynamics and molecular motors, chromosome attachment mechanisms, checkpoints, regulation of mitosis exit and cytokinesis. Mitotic disorders associated with cancer cells.
5. stem cells: cell differentiation, toti-, pluri- and multipotency, embryonic, adult and cancer stem cells
6. programmed cell death: apoptosis, autophagy, necrosis. Stages and modalities of apoptosis, signaling pathways involved. Role in the maintenance of homeostasis. Pathophysiological consequences of deregulation of programmed cell death.
Different study models are presented, in order to introduce the importance of the contribution of biological diversity in the discovery of cellular and molecular mechanisms, as well as in the understanding of human pathologies.
The program offers a refresher of knowledge and an in-depth study of the major concepts and methodologies of cell biology, organized around different themes:
1. Cytoskeleton: Introduction to the different types of cytoskeleton. Polymerization properties of actin and tubulin. Proteins associated with the cytoskeleton and regulating polymerization. Molecular motors. Principles of cell migration.
2. Cellular Adhesion & Signaling: Cell-cell and extracellular cell-matrix adhesive structures, their molecular and dynamic organization. Functions and regulations during development and pathogenesis. Regulation by signaling channels. Mechanotransduction.
3. Addressing and cell traffic: Ubiquitination and proteasome. Addressing to subcellular compartments, endocytosis and secretion pathways. The molecular bases of vesicular transport, budding, fusion, molecular motors. Signaling in membrane trafficking, genetic diseases linked to trafficking and diversion by pathogens.
4. Cell cycle: Historical introduction. Molecular regulation of the cell cycle. The mitotic spindle, microtubule and molecular motor dynamics, chromosome attachment mechanisms, checkpoints, regulation of mitosis output and cytokinesis. Mitotic disorders associated with cancer cells.
5. Stem cells: cell differentiation, toti-, pluri-and multipotency, embryonic, adult and cancer stem cells.
6. Programmed cell death: Apoptosis, autophagy, necrosis. Stages and modalities of apoptosis, signaling pathways involved. Role in maintaining homeostasis. Physiopathological consequences of deregulation of programmed cell death.
Different study models are presented, in order to introduce the importance of the contribution of biological diversity in the discovery of cellular and molecular mechanisms, as well as in the understanding of human pathologies
Molecular pharmacology and therapeutics
ECTS
5 credits
Component
Faculty of Pharmacy
Registration and Health Product Economics
ECTS
5 credits
Component
Faculty of Pharmacy
Analytical techniques for drug quality control
ECTS
5 credits
Component
Faculty of Pharmacy
Théra and Pharmaco Chemistry
ECTS
5 credits
Component
Faculty of Pharmacy
Molecular Pharmacochemistry section
ECTS
2 credits
Component
Faculty of Pharmacy
Therapeutic Chemistry - TC peptide synthesis
ECTS
3 credits
Component
Faculty of Pharmacy
R&D and Drug Registration
ECTS
5.5 credits
Component
Faculty of Pharmacy
Pharmacokinetics, pharmacodynamics and biopharmacy
ECTS
5 credits
Component
Faculty of Pharmacy
Advanced analysis techniques for Medi development.
ECTS
5 credits
Component
Faculty of Pharmacy
Fundamentals of health product engineering
ECTS
5 credits
Component
Faculty of Pharmacy
Basic element of health product engineering CT
Component
Faculty of Pharmacy
Fundamentals of health product engineering CC
Component
Faculty of Pharmacy
Introduction to aging and anti-aging
ECTS
5 credits
Component
Faculty of Pharmacy
Knowledge of the company and patent valuation
ECTS
5 credits
Component
Faculty of Science
You are a student of L3/M1 level in Languedoc-Roussillon? Would you like to work in small groups with students from other courses and in project mode, using a dormant scientific patent? To be accompanied and challenged by professional coaches of business creation? Register to PEPITE Patent Project to present a project of creation of innovative company based on the exploitation of a real patent provided by a local research team which will open its doors to you!
Why?
-Because you can create your own business whatever your field of study
To be selected by an incubator-type support structure
-To create a network in the field of entrepreneurship and innovation
PEPITE Patent Project, what is it? A Teaching Unit made up of strong times:
a 3-day "tool training" seminar
-regular meetings with the coaches
-Deliverables to be submitted: summary note, market study, business plan
a 10-minute final pitch to present your innovative company
Drug design: Introduction to drug design
ECTS
5 credits
Component
Faculty of Pharmacy
Microscopies and spectroscopies for biology
Level of study
BAC +4
Component
Faculty of Pharmacy
Industrial development of aging models
ECTS
5 credits
Component
Faculty of Pharmacy
Statistics and scientific watch
ECTS
3 credits
Component
Faculty of Pharmacy
Quality and technical/regulatory aspects: Technico réglem
ECTS
3.5 credits
Component
Faculty of Pharmacy
R&D and Drug Registration
ECTS
5.5 credits
Component
Faculty of Pharmacy
Statistics and scientific watch
ECTS
3 credits
Component
Faculty of Pharmacy
Framed Work R&D Medicines and Health Products
ECTS
5 credits
Component
Faculty of Pharmacy
TER Health product development pathway
ECTS
5 credits
Component
Faculty of Pharmacy
TER Aging and anti-aging start-up course
ECTS
5 credits
Component
Faculty of Pharmacy
TER Regulatory Environment track
ECTS
5 credits
Component
Faculty of Pharmacy
TER Structural Biology pathway
ECTS
5 credits
Component
Faculty of Pharmacy
TER Innovation in Health Chemistry pathway
ECTS
5 credits
Component
Faculty of Pharmacy
TER Health product analysis pathway
ECTS
5 credits
Component
Faculty of Pharmacy
Drug design: case studies
ECTS
2 credits
Component
Faculty of Pharmacy
Modeling molecule-target therapeutic interactions 1
ECTS
2 credits
Component
Faculty of Pharmacy
Modeling molecule-target therapeutic interactions 2
ECTS
2 credits
Component
Faculty of Pharmacy
Therapeutic peptides § Peptidomimetics
Component
Faculty of Pharmacy
Drug design: case studies
ECTS
2 credits
Component
Faculty of Pharmacy
Modeling molecule-target therapeutic interactions 1
ECTS
2 credits
Component
Faculty of Pharmacy
Modeling molecule-target therapeutic interactions 2
ECTS
2 credits
Component
Faculty of Pharmacy
Therapeutic peptides § Peptidomimetics
Component
Faculty of Pharmacy
Chemobiology (67% ENSCM)
Level of study
BAC +5
ECTS
2 credits
Component
Faculty of Science
The course will focus on organic chemistry and post-functionalization of biomolecules applied to peptides, proteins and nucleic acids (DNA and RNA) with applications in gene therapy, biosensing and design of probes for biological studies.
Hourly volumes* :
CM : 15 H
TD : 5 H
Structure-based drug design
ECTS
2 credits
Component
Faculty of Pharmacy
Nanotechnologies for health (EU PHARMACY)
ECTS
2 credits
Component
Faculty of Pharmacy
Tissue engineering and cell therapy
Component
Faculty of Pharmacy
News and recent advances in drug science
ECTS
4 credits
Component
Faculty of Pharmacy
Comnunication - Application of English
ECTS
3 credits
Component
Faculty of Pharmacy
Project management and risk management
Component
Faculty of Pharmacy
Chemobiology (67% ENSCM)
Level of study
BAC +5
ECTS
2 credits
Component
Faculty of Science
The course will focus on organic chemistry and post-functionalization of biomolecules applied to peptides, proteins and nucleic acids (DNA and RNA) with applications in gene therapy, biosensing and design of probes for biological studies.
Hourly volumes* :
CM : 15 H
TD : 5 H
Structure-based drug design
ECTS
2 credits
Component
Faculty of Pharmacy
Nanotechnologies for health (EU PHARMACY)
ECTS
2 credits
Component
Faculty of Pharmacy
Tissue engineering and cell therapy
Component
Faculty of Pharmacy
Innovation in health chemistry internship
ECTS
20 credits
Component
Faculty of Pharmacy
Tutored project Innovation in health chemistry
ECTS
10 credits
Component
Faculty of Pharmacy