Health

Structural Biology and Rational Design of Bioactive Molecules

  • ECTS

    120 credits

  • Duration

    2 years

  • Training structure

    School of Pharmacy

  • Language(s) of instruction

    French

Presentation

The course, supported by the Center for Structural Biology in Montpellier, leads to mastery of the approaches used for the structural analysis of biomolecules and their complexes for the in vitro analysis of interactions between biomolecules and their ligands.

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The advantages of the training program

Objectives

Train executives capable of designing new bioactive molecules through mastery of structural biology tools.

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Know-how and skills

  • Mastering biophysical techniques or methods of structural analysis applicable to the rational design of bioactive molecules.
  • Mastering structural analysis strategies (crystallography & X-rays, mass and NMR spectroscopy, electron microscopy, bioinformatics, etc.) for biological macromolecules, their pharmacological ligands, and biological macromolecule/ligand complexes.
  • Design and implement a rational screening protocol for a specific target biomolecule.
  • Synthesize data from different biophysical analysis methods.
  • Ensure effective communication at the interface between chemistry and biology in a laboratory/R&D department.
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Organization

Knowledge assessment

Open alternately

Type of contract

Apprenticeship contract, Professional training contract

Internships, supervised projects

Internship

Mandatory

  • In Master 1, supervised research work providing an introduction to the specific features of the course. A 2-month internship is preferred (minimum 1 month, long internship of 4/5 months possible depending on the course), starting in April. The Master 1 internship, lasting a minimum of 1 month, provides an introduction to research and development in the field of healthcare products.
  • In Master 2:
    • Supervised project in connection with the professional environment.
    • A minimum 5-month internship allows students to enter the professional world with a solid foundation of theoretical and methodological knowledge.
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Program

The program is structured over two years: a first year of Master 1 and a second year of Master 2 comprising six specialization tracks. Master 1 offers a core curriculum as well as specific teaching units, enabling students to acquire fundamental knowledge about medicines and health products. The specific teaching units prepare students for future specialization in Master 2.

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Select a program

M1 Medicinal Sciences and Health Products (P4)

  • Core Curriculum Units

    15 credits
    • English

      3 credits
    • Quality and technical-regulatory aspects: Technical regulations

      3.5 credits
      • Quality Department

      • Section Technical and regulatory aspects

    • R&D and Drug Registration

      5.5 credits
    • Statistics and scientific monitoring

      3 credits
  • Structural Biology

    5 credits
  • Therapeutic Chemistry and Pharmacology

    5 credits
    • Molecular Pharmacochemistry Section

      2 credits
    • Therapeutic Chemistry - Synthesis of TC Peptides

      3 credits
      • Therapeutic chemistry

        • Therapeutic Chemistry Written/CC

        • Therapeutic Chemistry Written

      • Peptide synthesis

  • Choice 1

    • Choose one of two options:

      • Molecular pharmacology and therapeutics

        5 credits
      • Analysis Techniques for Drug Quality Control

        5 credits
  • Microscopy and spectroscopy for biology

  • Drug design: Introduction to drug design

    5 credits
  • Choice 2

    • Choose one of two options:

      • Advanced Analysis Techniques for Media Development.

        5 credits
      • Knowledge of the company and patent valuation

        5 credits
  • Long internship

    15 credits
  • Internship

    10 credits
  • TER course in Structural Biology

    5 credits

M2 Structural Biology and Rational Design of Bioactive Molecules

  • Core curriculum

    • Recent news and advances in pharmaceutical sciences

      4 credits
    • Communication - English Application

      3 credits
    • Project management and risk management

  • Specific ECTS credits

    • Drug design: case studies

      2 credits
    • Biological NMR: structure, interactions, molecule screening

      6 credits
    • Biocrystallography: protein structure and screening

      4.5 credits
    • Preparative and analytical biochemistry

      5 credits
    • Structural bioinformatics

      2.5 credits
  • Supervised project in structural biology

    10 credits
  • Structural Biology Internship

    20 credits

Admission

Admission requirements

The Master 1 program is open to students coming from a scientific bachelor's degree program that provides a solid foundation in life sciences, biology, or chemistry (including physical and chemical sciences), consistent with the desired course of study and a suitable career plan.

The Master 2 is open to

  • Holders of a Master's degree in Pharmaceutical Sciences
  • Students who have successfully completed DFASP2 or DFASM3, pharmacy or medicine interns
  • Holders of a degree in pharmacy, medicine, or veterinary medicine.
  • Candidates benefiting from prior learning assessment
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Registration procedures

Master's 1

  • studying in France (for non-EU students)
  • You are not (or have not been for more than a year) a student and would like to resume your studies through continuing education. In this case, please contact Mrs. Avelli in order to obtain administrative information.

Master's degree

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Target audience

For M1: L3 or BUT in Life Sciences, Biology, or Chemistry for students who have graduated in an EU country. M1, M2, Pharmacy for students from outside the EU.    

For the M2: holder of a Master 1 in pharmaceutical sciences or health products, student in DFASP2 or DFASM3, intern in Pharmacy or Medicine.

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And after

Continuing education

This program allows students to enroll in doctoral schools in the fields of biology, chemistry, and physics, or to obtain another master's degree to acquire dual expertise.

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Gateways and reorientation

Possible pathways at the end of Master's 1 to Master's 2 programs in the same field of study in Biology, Health, and Health Engineering.

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Professional integration

  • Project managers
  • Design engineers
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