Health

Structural Biology and Rational Design of Bioactive Molecules

  • ECTS

    120 credits

  • Duration

    2 years

  • Training Structure

    School of Pharmacy

  • Language(s) of Instruction

    French

Overview

The program, affiliated with the Montpellier Center for Structural Biology, provides students with a thorough understanding of the methods used for the structural analysis of biomolecules and their complexes, as well as for the in vitro analysis of interactions between biomolecules and their ligands.

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The Benefits of the Training Program

Objectives

To train professionals capable of designing new bioactive molecules through mastery of structural biology tools.

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Expertise and Skills

  • Master the biophysical techniques or methods of structural analysis applicable to the rational design of bioactive molecules.
  • Master structural analysis strategies (crystallography and X-rays, mass spectroscopy and NMR, electron microscopy, bioinformatics, etc.) for biological macromolecules, their pharmacological ligands, and biological macromolecule/ligand complexes
  • Design and implement a rational screening protocol for a specific target biomolecule
  • Synthesize data from various biophysical analysis methods.
  • Ensure effective communication at the intersection of chemistry and biology within an R&D laboratory or department.
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Organization

Knowledge Assessment

Open on an alternating basis

Contract Type

Apprenticeship Contract, Professional Training Contract

Internships, supervised projects

Internship

Required

  • In the first year of the Master’s program, students engage in supervised research to gain an introduction to the specific aspects of their chosen track. A 2-month internship is preferred (minimum of one month; a 4- to 5-month internship is possible depending on the track), beginning in April. The first-year Master’s internship, which lasts at least one month, provides an introduction to research and development in the field of health products.
  • In the second year of the Master's program:
    • A supervised project in collaboration with the professional community.
    • An internship lasting at least 5 months enables students to enter the workforce based on a solid foundation of theoretical and methodological knowledge.
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Program

The program is structured over two years: a first year (Master 1) and a second year (Master 2) comprising six specialization tracks. The Master 1 program offers a core curriculum as well as specific course units, enabling students to acquire fundamental knowledge about medications and health products. The specific course units prepare students for their future specialization in the Master 2 program.

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Select a program

M1 Pharmaceutical Sciences and Health Products (P4)

  • UEs Core Curriculum

    15 credits
    • English

      3 credits
    • Quality and Technical and Regulatory Aspects: Technical and Regulatory

      3.5 credits
      • Quality Department

      • Section: Technical and Regulatory Aspects

    • R&D and Drug Registration

      5.5 credits
    • Statistics and Scientific Monitoring

      3 credits
  • Structural Biology

    5 credits
  • Therapeutic and Pharmaceutical Chemistry

    5 credits
    • Molecular Pharmacochemistry Section

      2 credits
    • Therapeutic Chemistry - Synthesis of TC Peptides

      3 credits
      • Therapeutic Chemistry

        • Therapeutic Chemistry—Written Exam/CC

        • Therapeutic Chemistry (Written Exam)

      • Peptide Synthesis

  • Option 1

    • Choose one of the following two options:

      • Molecular and Therapeutic Pharmacology

        5 credits
      • Analytical Techniques for Drug Quality Control

        5 credits
  • Microscopy and Spectroscopy for Biology

  • Drug Design: An Introduction to Drug Design

    5 credits
  • Option 2

    • Choose one of the following two options:

      • Advanced Analysis Techniques for Media Development.

        5 credits
      • Understanding the Company and Maximizing the Value of Patents

        5 credits
  • Long-term internship

    15 credits
  • Internship

    10 credits
  • TER Structural Biology Track

    5 credits

M2 in Structural Biology and Rational Design of Bioactive Molecules

  • Common Core Curriculum

    • News and Recent Advances in Pharmaceutical Sciences

      4 credits
    • Communication - Using English

      3 credits
    • Project Management and Risk Management

  • Specific UEs

    • Drug Design: Case Studies

      2 credits
    • Biological NMR: Structure, Interactions, and Molecular Screening

      6 credits
    • Biocrystallography: Protein Structure and Screening

      4.5 credits
    • Preparative and Analytical Biochemistry

      5 credits
    • Structural Bioinformatics

      2.5 credits
  • Supervised Project: Structural Biology Track

    10 credits
  • Internship in Structural Biology

    20 credits

Admission

Admission Requirements

The Master 1 program is open to students entering the program directly from a third-year science degree (L3) that provides a solid foundation in life sciences, biology, or chemistry (including physical and chemical sciences), provided their academic background aligns with the desired track and they have a suitable career plan.

The Master 2 program is open to

  • Holders of a Master's 1 in Pharmaceutical Sciences
  • Students who have successfully completed DFASP2 or DFASM3, or pharmacy or medical residents
  • Holders of a degree in pharmacy, medicine, or veterinary medicine.
  • Applicants with prior learning recognized
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Registration Procedures

Master's Degree, Year 1

  • Studying in France (for non-EU students)
  • You are not a student (or have not been one for more than a year) and would like to resume your studies through continuing education. In that case, please contact Ms. Avelli in order to obtain administrative information.

Master's Degree (Year 2)

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Target Audience

For the M1: A bachelor’s degree (L3) or a Bachelor’s degree (BUT) in Life Sciences, Biology, or Chemistry for students who graduated in an EU country. M1, M2, or Pharmacy for non-EU students.    

For the M2: Holders of a Master 1 degree in pharmaceutical sciences or health products; students in the DFASP2 or DFASM3 programs; or residents in pharmacy or medicine.

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And then

Continuing Education

This program allows students to apply to doctoral schools in the fields of biology, chemistry, and physics, or to earn another master’s degree to gain dual expertise.

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Transition Programs and Reorientation

Possible pathways from the end of the first year of the master's program to the second year of master's programs in the same field of study in Biology, Health, and Health Engineering.

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Employment Placement

  • Project Managers
  • Design Engineers
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