The aim of this resolutely trans-disciplinary course is to provide the skills needed to effectively manage and exploit data of various origins and types, particularly those with a spatial component. The course is divided into three complementary sections. The first deals with the issues inherent in data compilation and the solutions provided by database management systems (DBMS): from database design to queries. The second covers geographic information systems (GIS): from cartographic representation to geoprocessing. Finally, the third axis presents the diversity of spatial analysis tools for quantitative exploitation of spatial data, from metrics to statistical tests.