Study level
BAC +3
ECTS
5 credits
Component
Faculty of Science
Description
Functional genetics aims to better understand the relationships between genotype and phenotype. This course integrates various aspects of the analysis of gene and genome function at the whole-genome level using in vivo approaches, as well as transcriptional and expression regulation of eukaryotic genomes. The course is illustrated by concrete examples of developmental genetics in physiological and pathological contexts.
Objectives
-Knowledge :
Concepts and methods for understanding the phenotype-genotype relationship
Gene structure: coding versus non-coding regions, Cis-Trans effects
Regulation of eukaryotic gene expression
Genetic screens and model organisms (forward genetics)
Techniques for generating genetically modified organisms (reverse genetics)
-Know-how :
Use of DNA manipulation techniques and generation of genetically modified organisms
Interpretation of genetic analysis results
-People skills :
Ethical behavior (use of model organisms, plagiarism, cheating in science, etc.)
Methodical analysis of genetic analysis results
Being pragmatic
Being curious
Teaching hours
- Functional genetics - CMLecture24h
- Functional genetics - TDTutorial18h
Necessary prerequisites
MENDELIAN GENETICS, NOTIONS OF POPULATION AND HUMAN GENETICS