ECTS
6 credits
Component
Faculty of Science
List of courses
Choice of 1 of 3
Biology of Symbiotic and Parasitic Interactions
ECTS
6 credits
Component
Faculty of Science
The general objective of this course is to deepen the concepts necessary for the study of symbiotic interactions, whether parasitic or mutualistic. For that we will approach the specificities but also the ubiquity of the parasitic way of life in the tree of life. The defense mechanisms of host organisms, the notions of promotion and manipulation, the consequences of host-symbiont interactions on life history traits as well as the influence of these interactions in the diversification of organisms will be discussed.
The practical work will be an opportunity to deepen these concepts on some major models of interactions involving symbionts (viruses, bacteria, unicellular and multicellular eukaryotes) and hosts (uni- and multicellular).
Food microbiology and toxicology 2
ECTS
3 credits
Component
Faculty of Science
Food microbiology and toxicology 1
ECTS
3 credits
Component
Faculty of Science
Molecular basis of infectious diseases
Component
Faculty of Science
This UE is mainly composed of theoretical courses dealing with molecular aspects of infectious diseases (bacteriology, virology, parasitology)
Bacteriology: The nature of infectious agents. Methods of studying pathogenesis (in vivo in vitro, in silico and post-genomic study technologies) Strategies of pathogenic bacteria to survive in organisms: Bacterial adhesion to eukaryotic cells, antigenic variation and phase variation, invasion of non-phagocytic eukaryotic cells, mechanisms of resistance to phagocytosis, mechanisms of survival of bacteria in phagocytic cells, management of membrane permeability, bacterial secretion systems (type I, II, III, IV, V, and VI), mechanisms of iron acquisition, bacterial exotoxins, bacterial biofilms, examples of environmental regulations (Thermo-regulation, Quorum sensing...)).
Parasitology: Organization and cellular physiology of major pathogens in parasitic unicellular eukaryotes (invasion and modification of the host cell; metabolic characteristics and therapeutic targets); Genetics and molecular biology (genome organization, antigenic variation); Physiopathology and escape from the immune response
Virology: Molecular mechanisms of the viral cycle; Expression of viral genomes; Transformation by viruses; Viral replication strategy; Plasticity of viral genomes; Structural importance of viruses in host interaction;