ECTS
4 credits
Component
Faculty of Science
Description
The EU is organized into five major themes:
Theme 1: Gene mapping and recombination. Concepts of molecular biology related to gene expression, DNA repair and epigenetic processes.
Theme 2: Introduction to molecular evolution: Measuring the intensity of selection in genetic divergence. Molecular clock and variation in evolutionary rates created by the action of natural selection. Neutralist theory of evolution.
Theme 3: Introduction to genomics: composition and size of genomes. Importance of repeated elements. Notion of genetic linkage and local effect of selection. Influence of demography.
Theme 4: Molecular tools for biodiversity: Barcoding, eDNA, metabarcoding. Molecular taxonomy. Limitations of hybridization. Applications in conservation.
Theme 5: Extranuclear heredity. Symbiosis, parasitism and co-evolution (intra-cellular: e.g. Wolbachia). Notion of extended phenotype.
Necessary pre-requisites
- Mendelian heredity (seen in L1) Dominance, Polyallelism, Pleiotropy, Gene interactions.
- Structure and Expression of DNA (seen in L2)
Knowledge control
|
test |
coefficient |
Nb of hours |
Nb Sessions |
Organization (SDS or local) |
|
Written |
1/3 |
2H |
|
MSDS |
|
Continuous control |
1/5 |
Personal work on computers |
|
local |
|
TP |
1/5 |
0.45H |
|
local |
|
Oral |
1/4 |
3H |
|
local |
Additional information
The practical sessions will be computer sessions. The aim of the course is also to provide an introduction to genetic data analysis (bioinformatics) using software as well as basic programming information (loop, test) using the R language which has the advantage of being used in other courses (especially in statistics).
Targeted competencies
-To know the mechanisms and processes at the origin of biodiversity (K1)
-Know the tools for describing biodiversity from the gene to the biosphere (K4)
-Know and know how to implement the different approaches and tools used in evolutionary biology and ecology: observation, sampling, experimentation and statistical analysis (K6)
-To know the process of knowledge formation in different disciplines (hypotheses, experimental results, polemical results, mathematical theories, scientific facts) (L1)
-Know how to mobilize concepts and tools from different disciplines to analyze a document, an observation or the result of an experiment (L3)
-Know how to make an oral presentation and a scientific written report, using illustrations and a presentation adapted to the public concerned, with the help of adapted computer tools (L6)